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6ZQF
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BU of 6zqf by Molmil
Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-B (Poly-Ala)
分子名称: 18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ...
著者Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R.
登録日2020-07-09
公開日2020-09-23
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献90 S pre-ribosome transformation into the primordial 40 S subunit.
Science, 369, 2020
6HCM
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BU of 6hcm by Molmil
Structure of the rabbit collided di-ribosome (stalled monosome)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
著者Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
登録日2018-08-15
公開日2018-10-17
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6ZXF
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BU of 6zxf by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - State G
分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R.
登録日2020-07-29
公開日2020-12-02
最終更新日2020-12-09
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for the final steps of human 40S ribosome maturation.
Nature, 587, 2020
5YZG
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BU of 5yzg by Molmil
The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y.
登録日2017-12-14
公開日2018-08-08
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure of a human catalytic step I spliceosome
Science, 359, 2018
6IP6
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BU of 6ip6 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
登録日2018-11-02
公開日2019-05-29
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6ZXD
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BU of 6zxd by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - State F1
分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R.
登録日2020-07-29
公開日2020-12-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for the final steps of human 40S ribosome maturation.
Nature, 587, 2020
7MQ8
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BU of 7mq8 by Molmil
Cryo-EM structure of the human SSU processome, state pre-A1
分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Vanden Broeck, A, Singh, S, Klinge, S.
登録日2021-05-05
公開日2021-09-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Nucleolar maturation of the human small subunit processome.
Science, 373, 2021
6ZVH
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BU of 6zvh by Molmil
EDF1-ribosome complex
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Best, K.M, Denk, T, Cheng, J, Thoms, M, Berninghausen, O, Beckmann, R.
登録日2020-07-24
公開日2020-08-19
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献EDF1 coordinates cellular responses to ribosome collisions.
Elife, 9, 2020
6ZXE
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BU of 6zxe by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - State F2
分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R.
登録日2020-07-29
公開日2020-12-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for the final steps of human 40S ribosome maturation.
Nature, 587, 2020
7MQ9
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BU of 7mq9 by Molmil
Cryo-EM structure of the human SSU processome, state pre-A1*
分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Vanden Broeck, A, Singh, S, Klinge, S.
登録日2021-05-05
公開日2021-09-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献Nucleolar maturation of the human small subunit processome.
Science, 373, 2021
8UW3
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BU of 8uw3 by Molmil
Human LINE-1 retrotransposon ORF2 protein engaged with template RNA in elongation state
分子名称: Complementary DNA, LINE-1 retrotransposable element ORF2 protein, THYMIDINE-5'-TRIPHOSPHATE, ...
著者Thawani, A, Florez Ariza, A.J, Collins, K, Nogales, E.
登録日2023-11-06
公開日2023-12-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Template and target-site recognition by human LINE-1 in retrotransposition.
Nature, 626, 2024
8Y6O
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BU of 8y6o by Molmil
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
登録日2024-02-02
公開日2024-03-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
7LS2
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BU of 7ls2 by Molmil
80S ribosome from mouse bound to eEF2 (Class I)
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Loerch, S, Smith, P.R, Kunder, N, Stanowick, A.D, Lou, T.-F, Campbell, Z.T.
登録日2021-02-17
公開日2021-11-03
最終更新日2021-12-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.
Nat Commun, 12, 2021
7LS1
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BU of 7ls1 by Molmil
80S ribosome from mouse bound to eEF2 (Class II)
分子名称: 28S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Loerch, S, Smith, P.R, Kunder, N, Stanowick, A.D, Lou, T.-F, Campbell, Z.T.
登録日2021-02-17
公開日2021-11-03
最終更新日2021-12-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.
Nat Commun, 12, 2021
6ZXG
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BU of 6zxg by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - State H1
分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R.
登録日2020-07-29
公開日2020-12-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis for the final steps of human 40S ribosome maturation.
Nature, 587, 2020
8OHD
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BU of 8ohd by Molmil
60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native)
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R.
登録日2023-03-21
公開日2024-02-21
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024
6ZP4
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BU of 6zp4 by Molmil
SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-07-08
公開日2020-07-29
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6Y6X
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BU of 6y6x by Molmil
Tetracenomycin X bound to the human ribosome
分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Buschauer, R, Cheng, J, Berninghausen, O, Beckmann, R, Wilson, D.N.
登録日2020-02-27
公開日2020-07-08
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020
7AH8
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BU of 7ah8 by Molmil
NF-Y bound to suramin inhibitor
分子名称: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, CITRATE ANION, GLYCEROL, ...
著者Nardone, V, Chaves-Sanjuan, A, Lapi, M, Nardini, M.
登録日2020-09-24
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.70001364 Å)
主引用文献Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin.
Cells, 9, 2020
7B7S
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BU of 7b7s by Molmil
CDK2/cyclin A2 in complex with 3H-pyrazolo[4,3-f]quinoline-based derivative HSD1368
分子名称: 7-(3-(trifluoromethyl)-1H-pyrazol-4yl)-3,8,10,11-tetrahydropyrazolo[4,3-f]thiopyrano[3,4-c]quinoline 9-oxide, Cyclin-A2, Cyclin-dependent kinase 2, ...
著者Djukic, S, Skerlova, J, Rezacova, P.
登録日2020-12-11
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献3 H -Pyrazolo[4,3- f ]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo.
J.Med.Chem., 64, 2021
8B3F
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BU of 8b3f by Molmil
Pol II-CSB-CSA-DDB1-ELOF1
分子名称: DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ...
著者Kokic, G, Cramer, P.
登録日2022-09-16
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Pol II-CSB-CSA-DDB1-ELOF1 structure.
To Be Published
8B3D
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BU of 8b3d by Molmil
Structure of the Pol II-TCR-ELOF1 complex.
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA damage-binding protein 1, ...
著者Kokic, G, Cramer, P.
登録日2022-09-16
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structure of the Pol II-TCR-ELOF1 complex.
To Be Published
7MQA
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BU of 7mqa by Molmil
Cryo-EM structure of the human SSU processome, state post-A1
分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Vanden Broeck, A, Singh, S, Klinge, S.
登録日2021-05-05
公開日2021-09-22
最終更新日2021-09-29
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Nucleolar maturation of the human small subunit processome.
Science, 373, 2021
5LM7
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BU of 5lm7 by Molmil
Crystal structure of the lambda N-Nus factor complex
分子名称: 30S ribosomal protein S10, Antitermination protein N, N utilization substance protein B homolog, ...
著者Said, N, Santos, K, Weber, G, Wahl, M.C.
登録日2016-07-29
公開日2017-04-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
7R4X
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BU of 7r4x by Molmil
Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Pellegrino, S, Dent, K.C, Spikes, T, Warren, A.J.
登録日2022-02-09
公開日2023-02-22
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.15 Å)
主引用文献Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 angstrom resolution.
Nucleic Acids Res., 51, 2023

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