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3F1P
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Crystal structure of a high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains
分子名称: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
3F1O
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Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with an internally-bound artificial ligand
分子名称: 1,2-ETHANEDIOL, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, ...
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
3F1N
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Crystal structure of a high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with internally bound ethylene glycol.
分子名称: 1,2-ETHANEDIOL, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.479 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
3AY5
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BU of 3ay5 by Molmil
Crystal structure of HHM (human homologue of murine maternal Id-like molecule)
分子名称: Cyclin-D1-binding protein 1
著者Seto, A, Ishitani, R, Nureki, O.
登録日2011-04-28
公開日2012-03-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition.
Embo J., 31, 2012
2YPB
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Structure of the SCL:E47 complex bound to DNA
分子名称: EBOX FORWARD, EBOX REVERSE, T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1, ...
著者El Omari, K, Hoosdally, S.J, Tuladhar, K, Karia, D, Ponsele, E, Platonova, O, Vyas, P, Patient, R, Porcher, C, Mancini, E.J.
登録日2012-10-30
公開日2013-07-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4, 2013
2YPA
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Structure of the SCL:E47:LMO2:LDB1 complex bound to DNA
分子名称: EBOX FORWARD, EBOX REVERSE, LIM DOMAIN-BINDING PROTEIN 1, ...
著者El Omari, K, Hoosdally, S.J, Tuladhar, K, Karia, D, Ponsele, E, Platonova, O, Vyas, P, Patient, R, Porcher, C, Mancini, E.J.
登録日2012-10-30
公開日2013-07-31
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4, 2013
2VRR
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BU of 2vrr by Molmil
Structure of SUMO modified Ubc9
分子名称: FORMIC ACID, SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, ...
著者Knipscheer, P, Flotho, A, Klug, H, Olsen, J.V, van Dijk, W.J, Fish, A, Johnson, E.S, Mann, M, Sixma, T.K, Pichler, A.
登録日2008-04-13
公開日2008-08-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Ubc9 sumoylation regulates SUMO target discrimination.
Mol. Cell, 31, 2008
2UYZ
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Non-covalent complex between Ubc9 and SUMO1
分子名称: SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, SUMO-CONJUGATING ENZYME UBC9
著者Knipscheer, P, van Dijk, W.J, Olsen, J.V, Mann, M, Sixma, T.K.
登録日2007-04-21
公開日2007-06-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation.
EMBO J., 26, 2007
2QL2
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BU of 2ql2 by Molmil
Crystal Structure of the basic-helix-loop-helix domains of the heterodimer E47/NeuroD1 bound to DNA
分子名称: DNA (5'-D(*DAP*DGP*DGP*DAP*DCP*DCP*DAP*DGP*DAP*DTP*DGP*DGP*DCP*DCP*DTP*DA)-3'), DNA (5'-D(*DTP*DAP*DGP*DGP*DCP*DCP*DAP*DTP*DCP*DTP*DGP*DGP*DTP*DCP*DCP*DT)-3'), Neurogenic differentiation factor 1, ...
著者Rose, R.B, Longo, A, Guanga, G.P.
登録日2007-07-12
公開日2008-11-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition.
Biochemistry, 47, 2008
2MJV
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BU of 2mjv by Molmil
Solution structures of second bromodomain of Brd4 with di-acetylated Twist peptide
分子名称: Bromodomain-containing protein 4, Twist-related protein 1
著者Zeng, L, Zhou, M.
登録日2014-01-16
公開日2014-03-19
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer.
Cancer Cell, 25, 2014
2MH3
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BU of 2mh3 by Molmil
NMR structure of the basic helix-loop-helix region of the transcriptional repressor HES-1
分子名称: Transcription factor HES-1
著者Wienk, H, Popovic, M, Coglievina, M, Boelens, R, Pongor, S, Pintar, A.
登録日2013-11-15
公開日2014-02-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The basic helix-loop-helix region of the transcriptional repressor hairy and enhancer of split 1 is preorganized to bind DNA.
Proteins, 82, 2014
2MH0
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Solution NMR structure of the p300 Taz2:ETAD1 complex
分子名称: Histone acetyltransferase p300, Transcription factor E2-alpha
著者Langelaan, D.N, Smith, S.P, Chitayat, S.
登録日2013-11-12
公開日2014-11-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural insights into TAZ2 domain-mediated CBP/p300 recruitment by transactivation domain 1 of the lymphopoietic transcription factor E2A.
J.Biol.Chem., 295, 2020
2LFH
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BU of 2lfh by Molmil
Solution NMR Structure of the Helix-loop-Helix Domain of Human ID3 Protein, Northeast Structural Genomics Consortium Target HR3111A
分子名称: DNA-binding protein inhibitor ID-3
著者Eletsky, A, Wang, D, Kohan, E, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2011-06-30
公開日2011-07-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of the Helix-loop-Helix Domain of Human ID3 Protein, Northeast Structural Genomics Consortium Target HR3111A
To be Published
2KWF
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BU of 2kwf by Molmil
The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
分子名称: CREB-binding protein, Transcription factor 4
著者Denis, C.M, Chitayat, S, Plevin, M.J, Liu, S, Spencer, H.L, Ikura, M, LeBrun, D.P, Smith, S.P.
登録日2010-04-08
公開日2011-07-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
To be Published
2K7S
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BU of 2k7s by Molmil
Human ARNT C-Terminal PAS Domain, 3 Residue IB slip
分子名称: Aryl hydrocarbon receptor nuclear translocator
著者Evans, M.R, Card, P.B, Gardner, K.H.
登録日2008-08-20
公開日2009-01-20
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space
Proc.Natl.Acad.Sci.USA, 106, 2009
2A24
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BU of 2a24 by Molmil
HADDOCK Structure of HIF-2a/ARNT PAS-B Heterodimer
分子名称: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain protein 1
著者Card, P.B, Erbel, P.J, Gardner, K.H.
登録日2005-06-21
公開日2006-01-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.
J.Mol.Biol., 353, 2005
1X0O
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BU of 1x0o by Molmil
human ARNT C-terminal PAS domain
分子名称: Aryl hydrocarbon receptor nuclear translocator
著者Card, P.B, Erbel, P.J, Gardner, K.H.
登録日2005-03-25
公開日2005-10-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural Basis of ARNT PAS-B Dimerization: Use of a Common Beta-sheet Interface for Hetero- and Homodimerization.
J.Mol.Biol., 353, 2005
1U9B
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BU of 1u9b by Molmil
MURINE/HUMAN UBIQUITIN-CONJUGATING ENZYME UBC9
分子名称: UBIQUITIN-CONJUGATING ENZYME E9
著者Tong, H, Hateboer, G, Perrakis, A, Bernards, R, Sixma, T.K.
登録日1997-05-20
公開日1997-07-07
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system.
J.Biol.Chem., 272, 1997
1U9A
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BU of 1u9a by Molmil
HUMAN UBIQUITIN-CONJUGATING ENZYME UBC9
分子名称: UBIQUITIN-CONJUGATING ENZYME
著者Tong, H, Hateboer, G, Perrakis, A, Bernards, R, Sixma, T.K.
登録日1997-02-11
公開日1997-05-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system.
J.Biol.Chem., 272, 1997
1NLW
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BU of 1nlw by Molmil
Crystal structure of Mad-Max recognizing DNA
分子名称: 5'-D(*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3', MAD PROTEIN, MAX PROTEIN
著者Nair, S.K, Burley, S.K.
登録日2003-01-07
公開日2003-02-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structures of Myc-Max and Mad-Max recognizing DNA: Molecular bases of regulation by proto-oncogenic transcription factors
Cell(Cambridge,Mass.), 112, 2003
1NKP
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BU of 1nkp by Molmil
Crystal structure of Myc-Max recognizing DNA
分子名称: 5'-D(*CP*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3', Max protein, Myc proto-oncogene protein
著者Nair, S.K, Burley, S.K.
登録日2003-01-03
公開日2003-02-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray structures of Myc-Max and Mad-Max recognizing DNA: Molecular bases of regulation by proto-oncogenic transcription factors
Cell(Cambridge,Mass.), 112, 2003
1MDY
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BU of 1mdy by Molmil
CRYSTAL STRUCTURE OF MYOD BHLH DOMAIN BOUND TO DNA: PERSPECTIVES ON DNA RECOGNITION AND IMPLICATIONS FOR TRANSCRIPTIONAL ACTIVATION
分子名称: DNA (5'-D(*TP*CP*AP*AP*CP*AP*GP*CP*TP*GP*TP*TP*GP*A)-3'), PROTEIN (MYOD BHLH DOMAIN)
著者Ma, P.C.M, Rould, M.A, Weintraub, H, Pabo, C.O.
登録日1994-06-09
公開日1994-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of MyoD bHLH domain-DNA complex: perspectives on DNA recognition and implications for transcriptional activation.
Cell(Cambridge,Mass.), 77, 1994
1HLO
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BU of 1hlo by Molmil
THE CRYSTAL STRUCTURE OF AN INTACT HUMAN MAX-DNA COMPLEX: NEW INSIGHTS INTO MECHANISMS OF TRANSCRIPTIONAL CONTROL
分子名称: DNA (5'-D(*AP*CP*CP*AP*CP*GP*TP*GP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*CP*AP*CP*GP*TP*GP*GP*T)-3'), PROTEIN (TRANSCRIPTION FACTOR MAX)
著者Brownlie, P, Ceska, T.A, Lamers, M, Romier, C, Theo, H, Suck, D.
登録日1997-09-10
公開日1997-10-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control.
Structure, 5, 1997
1A0A
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PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4/DNA COMPLEX
分子名称: DNA (5'-D(*CP*TP*AP*GP*TP*CP*CP*CP*AP*CP*GP*TP*GP*TP*GP*AP*G )-3'), DNA (5'-D(*CP*TP*CP*AP*CP*AP*CP*GP*TP*GP*GP*GP*AP*CP*TP*AP*G )-3'), PROTEIN (PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4)
著者Shimizu, T, Toumoto, A, Ihara, K, Shimizu, M, Kyogoku, Y, Ogawa, N, Oshima, Y, Hakoshima, T.
登録日1997-11-27
公開日1998-03-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition.
EMBO J., 16, 1997

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