PDB: 1550 件ウェブページステータス検索Chemie searchBIRD

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7MIC	Maize rayado fino virus protease in complex with Ubiquitin 分子名称: 3-AMINOPROPANE, GLYCEROL, RNA replication protein, ... 著者 Patel, A, Mark, B.L. 登録日 2021-04-16 公開日 2021-07-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 The endopeptidase of the maize-affecting Marafivirus type member maize rayado fino virus doubles as a deubiquitinase. J.Biol.Chem., 297, 2021
3SDL	Crystal structure of human ISG15 in complex with NS1 N-terminal region from influenza B virus, Northeast Structural Genomics Consortium Target IDs HX6481, HR2873, and OR2 分子名称: Non-structural protein 1, Ubiquitin-like protein ISG15 著者 Guan, R, Ma, L.-C, Krug, R.M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2011-06-09 公開日 2011-07-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structural basis for the sequence-specific recognition of human ISG15 by the NS1 protein of influenza B virus. Proc.Natl.Acad.Sci.USA, 108, 2011
5CVN	WDR48 (2-580):USP46~ubiquitin ternary complex 分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ... 著者 Harris, S.F, Yin, J. 登録日 2015-07-27 公開日 2015-10-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.36 Å) 主引用文献 Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46. Structure, 23, 2015
6CFP	CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE 分子名称: 1-{1-[(4-fluorophenyl)methyl]-2-methyl-1H-imidazol-4-yl}ethan-1-one, DIMETHYL SULFOXIDE, Ubiquitin-like protein SMT3,Polymerase acidic protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-02-15 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE To Be Published
3V6E	Crystal Structure of USP2 and a mutant form of Ubiquitin 分子名称: CHLORIDE ION, GLYCEROL, Ubiquitin, ... 著者 Neculai, M, Ernst, A, Sidhu, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2011-12-19 公開日 2012-12-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
6BVB	Crystal structure of HIF-2alpha-pVHL-elongin B-elongin C 分子名称: Elongin-B, Elongin-C, Hypoxia-Inducible Factor 2 alpha, ... 著者 Tarade, D, Ohh, M, Lee, J.E. 登録日 2017-12-12 公開日 2018-08-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 HIF-2 alpha-pVHL complex reveals broad genotype-phenotype correlations in HIF-2 alpha-driven disease. Nat Commun, 9, 2018
7M3Q	Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, ... 著者 Chowdhury, A, Singer, A.U, Ogunjimi, A.A, Teyra, J, Zhang, W, Sicheri, F, Sidhu, S.S. 登録日 2021-03-18 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) To be published
5IBK	Skp1-F-box in complex with a ubiquitin variant 分子名称: F-box/WD repeat-containing protein 7, Polyubiquitin-B, S-phase kinase-associated protein 1,S-phase kinase-associated protein 1 著者 Orlicky, S, Sicheri, F. 登録日 2016-02-22 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface. Proc.Natl.Acad.Sci.USA, 113, 2016
5HPS	System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1 and UbV P1.1 分子名称: Ubiquitin variant P1.1, WWP1 HECT 著者 Wu, K.-P, Mercredi, P.Y, Schulman, B.A. 登録日 2016-01-20 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
6EI1	Crystal structure of the covalent complex between deubiquitinase ZUFSP (ZUP1) and Ubiquitin-PA 分子名称: GLYCEROL, MALONATE ION, Polyubiquitin-B, ... 著者 Pichlo, C, Baumann, U, Hofmann, K, Hermanns, T. 登録日 2017-09-16 公開日 2018-03-07 最終更新日 2019-10-16 実験手法 X-RAY DIFFRACTION (1.732 Å) 主引用文献 A family of unconventional deubiquitinases with modular chain specificity determinants. Nat Commun, 9, 2018
3V60	Structure of S. cerevisiae PCNA conjugated to SUMO on lysine 164 分子名称: Proliferating cell nuclear antigen, SULFATE ION, Ubiquitin-like protein SMT3 著者 Armstrong, A.A, Mohideen, F, Lima, C.D. 登録日 2011-12-18 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012
3UQB	Crystal structure of a SMT Fusion PEPTIDYL-PROLYL CIS-TRANS ISOMERASE with surface mutation D44G from Burkholderia pseudomallei complexed with FK506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, Ubiquitin-like protein SMT3, Peptidyl-prolyl cis-trans isomerase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-11-19 公開日 2011-11-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
6BVA	Ubiquitin Variant (UbV.Fl10.1) bound to a human Skp1-Fbl10 fragment complex. 分子名称: Lysine-specific demethylase 2B, Polyubiquitin-B, S-phase kinase-associated protein 1 著者 Manczyk, N, Sicheri, F. 登録日 2017-12-12 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases. Structure, 26, 2018
5D6J	Crystal structure of a mycobacterial protein 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Acyl-CoA synthase, MAGNESIUM ION, ... 著者 Li, W.J, Bi, L.J. 登録日 2015-08-12 公開日 2016-03-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of FadD32, an enzyme essential for mycolic acid biosynthesis in mycobacteria. Sci Rep, 5, 2015
3V62	Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164 分子名称: ATP-dependent DNA helicase SRS2, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ... 著者 Armstrong, A.A, Mohideen, F, Lima, C.D. 登録日 2011-12-18 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012
5CVO	WDR48:USP46~ubiquitin ternary complex 分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ... 著者 Harris, S.F, Yin, J. 登録日 2015-07-27 公開日 2015-10-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.885 Å) 主引用文献 Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46. Structure, 23, 2015
5BZ0	Crystal structure of IBV papain-like protease PLpro C101S mutant in complex with ubiquitin 分子名称: Replicase polyprotein 1ab, Ubiquitin-40S ribosomal protein S27a, ZINC ION 著者 Kong, L.Y, Yan, L.M, Zhang, Y, Rao, Z.H. 登録日 2015-06-11 公開日 2016-06-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of IBV papain-like protease PLpro C101S mutant in complex with ubiquitin To Be Published
3SHQ	Crystal Structure of UBLCP1 分子名称: MAGNESIUM ION, UBLCP1 著者 Xiao, J, Engel, J.L. 登録日 2011-06-16 公開日 2011-10-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity. Proc.Natl.Acad.Sci.USA, 108, 2011
5CAW	Structure of Pediculus humanus Parkin bound to phospho-ubiquitin 分子名称: E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, SULFATE ION, ... 著者 Wauer, T, Komander, D. 登録日 2015-06-30 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Mechanism of phospho-ubiquitin-induced PARKIN activation. Nature, 524, 2015
3VUW	Crystal structure of A20 ZF7 in complex with linear ubiquitin, form I 分子名称: POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2012-07-09 公開日 2013-02-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
3VAW	Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase with surface mutation v3i from burkholderia pseudomallei complexed with fk506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, Ubiquitin-like protein SMT3,Peptidyl-prolyl cis-trans isomerase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-12-29 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
5C7M	CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT 分子名称: E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C 著者 Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) 登録日 2015-06-24 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.03 Å) 主引用文献 System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
3UF8	Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with a G95A surface mutation from Burkholderia pseudomallei complexed with FK506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, Ubiquitin-like protein SMT3, Peptidyl-prolyl cis-trans isomerase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-10-31 公開日 2011-11-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
5C23	Parkin (S65DUblR0RBR) 分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... 著者 Kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H. 登録日 2015-06-15 公開日 2015-07-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis. Embo J., 34, 2015
3V61	Structure of S. cerevisiae PCNA conjugated to SUMO on lysine 164 分子名称: BARIUM ION, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ... 著者 Armstrong, A.A, Mohideen, F, Lima, C.D. 登録日 2011-12-18 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012

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