PDB: 1515 件ウェブページステータス検索Chemie searchBIRD

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4KSK	Gumby/Fam105B in complex with ubiquitin 分子名称: Polyubiquitin-C, Protein FAM105B, SULFATE ION 著者 Ceccarelli, D.F, Juang, Y.-C, Sicheri, F. 登録日 2013-05-17 公開日 2013-06-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature, 498, 2013
5HPL	System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: Rsp5 and UbV R5.4 分子名称: Rsp5, Ubiquitin variant R5.4 著者 Wu, K.-P, Kamadurai, H.B, Schulman, B.A. 登録日 2016-01-20 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
4KSL	Gumby/Fam105B in complex with linear di-ubiquitin 分子名称: Polyubiquitin-C, Protein FAM105B 著者 Juang, Y.-C, Ceccarelli, D.F, Sicheri, F. 登録日 2013-05-17 公開日 2013-06-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature, 498, 2013
4K95	Crystal Structure of Parkin 分子名称: E3 ubiquitin-protein ligase parkin, ZINC ION 著者 Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K. 登録日 2013-04-19 公開日 2013-05-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (6.499 Å) 主引用文献 Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science, 340, 2013
3M63	Crystal structure of Ufd2 in complex with the ubiquitin-like (UBL) domain of Dsk2 分子名称: PENTAETHYLENE GLYCOL, POTASSIUM ION, Ubiquitin conjugation factor E4, ... 著者 Haenzelmann, P, Schindelin, H. 登録日 2010-03-15 公開日 2010-04-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The yeast E4 ubiquitin ligase Ufd2 interacts with the ubiquitin-like domains of Rad23 and Dsk2 via a novel and distinct ubiquitin-like binding domain. J.Biol.Chem., 285, 2010
4JIO	Bro1 V domain and ubiquitin 分子名称: BRO1, Ubiquitin 著者 Pashkova, N, Gakhar, L, Piper, R.C. 登録日 2013-03-06 公開日 2013-06-19 最終更新日 2013-07-10 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 The yeast alix homolog bro1 functions as a ubiquitin receptor for protein sorting into multivesicular endosomes. Dev.Cell, 25, 2013
3JSV	Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin 分子名称: NF-kappa-B essential modulator, Ubiquitin 著者 Yoshikawa, A, Sato, Y, Mimura, H, Yamashita, M, Yamagata, A, Fukai, S. 登録日 2009-09-11 公開日 2009-10-27 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin Febs Lett., 583, 2009
4LJO	Structure of an active ligase (HOIP)/ubiquitin transfer complex 分子名称: E3 ubiquitin-protein ligase RNF31, IMIDAZOLE, Polyubiquitin-C, ... 著者 Rana, R.R, Stieglitz, B, Koliopoulos, M.G, Morris-Davies, A.C, Christodoulou, E, Howell, S, Brown, N.R, Rittinger, K. 登録日 2013-07-05 公開日 2013-10-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.564 Å) 主引用文献 Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP. Nature, 503, 2013
5IBK	Skp1-F-box in complex with a ubiquitin variant 分子名称: F-box/WD repeat-containing protein 7, Polyubiquitin-B, S-phase kinase-associated protein 1,S-phase kinase-associated protein 1 著者 Orlicky, S, Sicheri, F. 登録日 2016-02-22 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface. Proc.Natl.Acad.Sci.USA, 113, 2016
5HPS	System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1 and UbV P1.1 分子名称: Ubiquitin variant P1.1, WWP1 HECT 著者 Wu, K.-P, Mercredi, P.Y, Schulman, B.A. 登録日 2016-01-20 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
4LCD	Structure of an Rsp5xUbxSna3 complex: Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3 分子名称: E3 ubiquitin-protein ligase RSP5, Protein SNA3, Ubiquitin 著者 Kamadurai, H.B, Miller, D, Schulman, B.A. 登録日 2013-06-21 公開日 2013-08-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3. Elife, 2, 2013
3N3K	The catalytic domain of USP8 in complex with a USP8 specific inhibitor 分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 8, ZINC ION 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Allali-Hassani, A, Lam, R, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium, Structural Genomics Consortium (SGC) 登録日 2010-05-20 公開日 2010-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
3M62	Crystal structure of Ufd2 in complex with the ubiquitin-like (UBL) domain of Rad23 分子名称: PENTAETHYLENE GLYCOL, POTASSIUM ION, UV excision repair protein RAD23, ... 著者 Haenzelmann, P, Schindelin, H. 登録日 2010-03-15 公開日 2010-04-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The yeast E4 ubiquitin ligase Ufd2 interacts with the ubiquitin-like domains of Rad23 and Dsk2 via a novel and distinct ubiquitin-like binding domain. J.Biol.Chem., 285, 2010
3MHS	Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ... 著者 Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C. 登録日 2010-04-08 公開日 2010-04-21 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structural insights into the assembly and function of the SAGA deubiquitinating module. Science, 328, 2010
4LJP	Structure of an active ligase (HOIP-H889A)/ubiquitin transfer complex 分子名称: E3 ubiquitin-protein ligase RNF31, Polyubiquitin-C, ZINC ION 著者 Rana, R.R, Stieglitz, B, Koliopoulos, M.G, Morris-Davies, A.C, Christodoulou, E, Howell, S, Brown, N.R, Rittinger, K. 登録日 2013-07-05 公開日 2013-10-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP. Nature, 503, 2013
3MTN	Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor 分子名称: CHLORIDE ION, GLYCEROL, UBIQUITIN VARIANT UBV.21.4, ... 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2010-04-30 公開日 2010-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
3KVF	Crystal structure of the I93M mutant of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester 分子名称: METHYL 4-AMINOBUTANOATE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L1 著者 Davies, C.W, Maiti, T.K, Das, C. 登録日 2009-11-30 公開日 2010-06-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation. Proc.Natl.Acad.Sci.USA, 107, 2010
3KW5	Crystal structure of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester 分子名称: METHYL 4-AMINOBUTANOATE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L1 著者 Maiti, T.K, Boudreaux, D.A, Das, C. 登録日 2009-11-30 公開日 2010-06-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation. Proc.Natl.Acad.Sci.USA, 107, 2010
3NHE	High Resolution Structure (1.26A) of USP2a in Complex with Ubiquitin 分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ZINC ION 著者 Schormann, N, DeLucas, L.J, Powell McCombs, D. 登録日 2010-06-14 公開日 2010-06-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 High resolution structure of USP2a in complex with ubiquitin To be Published
3TMP	The catalytic domain of human deubiquitinase DUBA in complex with ubiquitin aldehyde 分子名称: OTU domain-containing protein 5, Polyubiquitin-C 著者 Ma, X, Yin, J, Hymowitz, S, Starovasnik, M, Cochran, A. 登録日 2011-08-31 公開日 2012-01-11 最終更新日 2012-02-29 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Phosphorylation-dependent activity of the deubiquitinase DUBA. Nat.Struct.Mol.Biol., 19, 2012
3OLM	Structure and Function of a Ubiquitin Binding Site within the Catalytic Domain of a HECT Ubiquitin Ligase 分子名称: E3 ubiquitin-protein ligase RSP5, Ubiquitin 著者 Kim, H.C, Steffen, A, Chen, J, Huibregtse, J.M. 登録日 2010-08-26 公開日 2011-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.495 Å) 主引用文献 Structure and function of a HECT domain ubiquitin-binding site. Embo Rep., 12, 2011
3SHQ	Crystal Structure of UBLCP1 分子名称: MAGNESIUM ION, UBLCP1 著者 Xiao, J, Engel, J.L. 登録日 2011-06-16 公開日 2011-10-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity. Proc.Natl.Acad.Sci.USA, 108, 2011
3PRM	Structural analysis of a viral OTU domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with human ubiquitin 分子名称: Polyubiquitin-B (Fragment), RNA-directed RNA polymerase L 著者 Capodagli, G.C, McKercher, M.A, Baker, E.A, Masters, E.M, Brunzelle, J.S, Pegan, S.D. 登録日 2010-11-30 公開日 2011-01-26 最終更新日 2023-02-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural analysis of a viral ovarian tumor domain protease from the crimean-congo hemorrhagic Fever virus in complex with covalently bonded ubiquitin. J.Virol., 85, 2011
3UF8	Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with a G95A surface mutation from Burkholderia pseudomallei complexed with FK506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, Ubiquitin-like protein SMT3, Peptidyl-prolyl cis-trans isomerase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-10-31 公開日 2011-11-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
3PLV	Structure of Hub-1 protein in complex with Snu66 peptide (HINDII) 分子名称: 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Ubiquitin-like modifier HUB1 著者 Mishra, S.K, Ammon, T, Popowicz, G.M, Krajewski, M, Nagel, R.J, Ares, M, Holak, T.A, Jentsch, S. 登録日 2010-11-15 公開日 2011-06-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing. Nature, 474, 2011

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