4N0B
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![BU of 4n0b by Molmil](/molmil-images/mine/4n0b) | Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of GabT | 分子名称: | ACETYL GROUP, CALCIUM ION, HTH-type transcriptional regulatory protein GabR, ... | 著者 | Edayathumangalam, R, Wu, R, Garcia, R, Wang, Y, Wang, W, Kreinbring, C.A, Bach, A, Liao, J, Stone, T, Terwilliger, T, Hoang, Q.Q, Belitsky, B.R, Petsko, G.A, Ringe, D, Liu, D. | 登録日 | 2013-10-01 | 公開日 | 2013-10-30 | 最終更新日 | 2014-04-02 | 実験手法 | X-RAY DIFFRACTION (2.705 Å) | 主引用文献 | Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT. Proc.Natl.Acad.Sci.USA, 110, 2013
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4TV7
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![BU of 4tv7 by Molmil](/molmil-images/mine/4tv7) | |
6M4O
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![BU of 6m4o by Molmil](/molmil-images/mine/6m4o) | Cryo-EM structure of the monomeric SPT-ORMDL3 complex | 分子名称: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | 著者 | Li, S.S, Xie, T, Wang, L, Gong, X. | 登録日 | 2020-03-08 | 公開日 | 2021-02-10 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex. Nat.Struct.Mol.Biol., 28, 2021
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6M4N
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![BU of 6m4n by Molmil](/molmil-images/mine/6m4n) | Cryo-EM structure of the dimeric SPT-ORMDL3 complex | 分子名称: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | 著者 | Li, S.S, Xie, T, Wang, L, Gong, X. | 登録日 | 2020-03-07 | 公開日 | 2021-02-10 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex. Nat.Struct.Mol.Biol., 28, 2021
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4MGR
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![BU of 4mgr by Molmil](/molmil-images/mine/4mgr) | The crystal structure of Bacillus subtilis GabR, an autorepressor and PLP- and GABA-dependent transcriptional activator of gabT | 分子名称: | ACETATE ION, HTH-type transcriptional regulatory protein GabR, IMIDAZOLE, ... | 著者 | Wu, R, Edayathumangalam, R, Garcia, R, Wang, Y, Wang, W, Kreinbring, C.A, Bach, A, Liao, J, Stone, T, Terwilliger, T, Hoang, Q.Q, Belitsky, B.R, Petsko, G.A, Ringe, D, Liu, D. | 登録日 | 2013-08-28 | 公開日 | 2013-10-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT. Proc.Natl.Acad.Sci.USA, 110, 2013
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8C80
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![BU of 8c80 by Molmil](/molmil-images/mine/8c80) | Cryo-EM structure of the yeast SPT-Orm1-Monomer complex | 分子名称: | 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ERGOSTEROL, N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]hexacosanamide, ... | 著者 | Schaefer, J, Koerner, C, Parey, K, Januliene, D, Moeller, A, Froehlich, F. | 登録日 | 2023-01-18 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the ceramide-bound SPOTS complex. Nat Commun, 14, 2023
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8C81
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![BU of 8c81 by Molmil](/molmil-images/mine/8c81) | Cryo-EM structure of the yeast SPT-Orm1-Sac1 complex | 分子名称: | 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ERGOSTEROL, N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]hexacosanamide, ... | 著者 | Schaefer, J, Koerner, C, Parey, K, Januliene, D, Moeller, A, Froehlich, F. | 登録日 | 2023-01-18 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of the ceramide-bound SPOTS complex. Nat Commun, 14, 2023
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8C82
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![BU of 8c82 by Molmil](/molmil-images/mine/8c82) | Cryo-EM structure of the yeast SPT-Orm1-Dimer complex | 分子名称: | 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]hexacosanamide, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Schaefer, J, Koerner, C, Parey, K, Januliene, D, Moeller, A, Froehlich, F. | 登録日 | 2023-01-18 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the ceramide-bound SPOTS complex. Nat Commun, 14, 2023
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7CQI
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![BU of 7cqi by Molmil](/molmil-images/mine/7cqi) | Cryo-EM structure of the substrate-bound SPT-ORMDL3 complex | 分子名称: | ORM1-like protein 3, Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, ... | 著者 | Li, S.S, Xie, T, Wang, L, Gong, X. | 登録日 | 2020-08-11 | 公開日 | 2021-02-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex. Nat.Struct.Mol.Biol., 28, 2021
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7CQK
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![BU of 7cqk by Molmil](/molmil-images/mine/7cqk) | Cryo-EM structure of the substrate-bound SPT-ORMDL3 complex | 分子名称: | ORM1-like protein 3, Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, ... | 著者 | Li, S.S, Xie, T, Wang, L, Gong, X. | 登録日 | 2020-08-11 | 公開日 | 2021-02-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex. Nat.Struct.Mol.Biol., 28, 2021
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7K0I
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![BU of 7k0i by Molmil](/molmil-images/mine/7k0i) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7K0K
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![BU of 7k0k by Molmil](/molmil-images/mine/7k0k) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, 3KS-bound | 分子名称: | 3-Dehydrosphinganine, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7K0N
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![BU of 7k0n by Molmil](/molmil-images/mine/7k0n) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 2 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7K0O
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![BU of 7k0o by Molmil](/molmil-images/mine/7k0o) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 3 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7K0J
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![BU of 7k0j by Molmil](/molmil-images/mine/7k0j) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa protomer | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7K0Q
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![BU of 7k0q by Molmil](/molmil-images/mine/7k0q) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound | 分子名称: | Myriocin, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7K0L
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![BU of 7k0l by Molmil](/molmil-images/mine/7k0l) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, myriocin-bound | 分子名称: | Myriocin, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7K0P
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![BU of 7k0p by Molmil](/molmil-images/mine/7k0p) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 4 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7K0M
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![BU of 7k0m by Molmil](/molmil-images/mine/7k0m) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 1 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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8IAK
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![BU of 8iak by Molmil](/molmil-images/mine/8iak) | |
8IAJ
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![BU of 8iaj by Molmil](/molmil-images/mine/8iaj) | Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3A) complex | 分子名称: | N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, PYRIDOXAL-5'-PHOSPHATE, Protein ORM2, ... | 著者 | Xie, T, Gong, X. | 登録日 | 2023-02-08 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide. Cell Rep, 43, 2024
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8IAM
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![BU of 8iam by Molmil](/molmil-images/mine/8iam) | Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3D) complex | 分子名称: | Chimera of Long chain base biosynthesis protein 1 and Serine palmitoyltransferase 1, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Xie, T, Gong, X. | 登録日 | 2023-02-08 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide. Cell Rep, 43, 2024
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7YJ1
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![BU of 7yj1 by Molmil](/molmil-images/mine/7yj1) | Cryo-EM structure of SPT-ORMDL3 (ORMDL3-deltaN2) complex | 分子名称: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | 著者 | Xie, T, Liu, P, Gong, X. | 登録日 | 2022-07-19 | 公開日 | 2023-07-05 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis. Nat Commun, 14, 2023
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7YIU
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![BU of 7yiu by Molmil](/molmil-images/mine/7yiu) | Cryo-EM structure of the C6-ceramide-bound SPT-ORMDL3 complex | 分子名称: | HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)HEXANAMIDE, ORM1-like protein 3, ... | 著者 | Xie, T, Liu, P, Gong, X. | 登録日 | 2022-07-18 | 公開日 | 2023-07-05 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis. Nat Commun, 14, 2023
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7YJ2
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![BU of 7yj2 by Molmil](/molmil-images/mine/7yj2) | Cryo-EM structure of SPT-ORMDL3 (ORMDL3-N13A) complex | 分子名称: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | 著者 | Xie, T, Liu, P, Gong, X. | 登録日 | 2022-07-19 | 公開日 | 2023-07-05 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis. Nat Commun, 14, 2023
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