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8QAE
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X-ray crystal structure of a de novo designed single-chain antiparallel 6-helix alpha-helical barrel, sc-apCC-6-SLLA
分子名称: 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol, PENTAETHYLENE GLYCOL, sc-apCC-6-SLLA
著者Albanese, K.I, Petrenas, R, Woolfson, D.N.
登録日2023-08-22
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rationally seeded computational protein design of ɑ-helical barrels.
Nat.Chem.Biol., 2024
8QAG
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BU of 8qag by Molmil
X-ray crystal structure of a de novo designed single-chain parallel coiled-coil alpha-helical barrel with 6 inner helices, sc-CC-6-95
分子名称: DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, sc-CC-6-95
著者Petrenas, R, Albanese, K.I, Woolfson, D.N.
登録日2023-08-22
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Rationally seeded computational protein design of ɑ-helical barrels.
Nat.Chem.Biol., 2024
7JRP
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BU of 7jrp by Molmil
Plant Mitochondrial complex SC III2+IV from Vigna radiata
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Alpha-MPP, ...
著者Maldonado, M, Letts, J.A.
登録日2020-08-12
公開日2021-01-20
最終更新日2021-02-03
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atomic structures of respiratory complex III 2 , complex IV, and supercomplex III 2 -IV from vascular plants.
Elife, 10, 2021
1PP8
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BU of 1pp8 by Molmil
crystal structure of the T. vaginalis IBP39 Initiator binding domain (IBD) bound to the alpha-SCS Inr element
分子名称: 39 kDa initiator binding protein, ALPHA-SCS INR, SULFATE ION
著者Schumacher, M.A, Lau, A.O.T, Johnson, P.J.
登録日2003-06-16
公開日2003-11-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural Basis of Core Promoter Recognition in a Primitive Eukaryote
Cell(Cambridge,Mass.), 115, 2003
1JLL
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BU of 1jll by Molmil
Crystal Structure Analysis of the E197betaA Mutant of E. coli SCS
分子名称: COENZYME A, PHOSPHATE ION, SULFATE ION, ...
著者Fraser, M.E.
登録日2001-07-16
公開日2002-01-30
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Two glutamate residues, Glu 208 alpha and Glu 197 beta, are crucial for phosphorylation and dephosphorylation of the active-site histidine residue in succinyl-CoA synthetase.
Biochemistry, 41, 2002
1JKJ
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E. coli SCS
分子名称: COENZYME A, GLYCEROL, PHOSPHATE ION, ...
著者Fraser, M.E.
登録日2001-07-12
公開日2002-01-30
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Two glutamate residues, Glu 208 alpha and Glu 197 beta, are crucial for phosphorylation and dephosphorylation of the active-site histidine residue in succinyl-CoA synthetase.
Biochemistry, 41, 2002
3RHU
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BU of 3rhu by Molmil
Epitope backbone grafting by computational design for improved presentation of linear epitopes on scaffold proteins
分子名称: SC_1wnu
著者Azoitei, M.L, Ban, Y.A, Julien, J.P, Bryson, S, Schroeter, A, Kalyuzhniy, O, Porter, J.R, Adachi, Y, Baker, D, Szabo, E, Pai, E.F, Schief, W.R.
登録日2011-04-12
公開日2011-11-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope.
J.Mol.Biol., 415, 2012
1W1W
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BU of 1w1w by Molmil
Sc Smc1hd:Scc1-C complex, ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, SISTER CHROMATID COHESION PROTEIN 1, ...
著者Haering, C, Nasmyth, K, Lowe, J.
登録日2004-06-24
公開日2004-09-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure and stability of cohesin's Smc1-kleisin interaction.
Mol. Cell, 15, 2004
3AUV
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BU of 3auv by Molmil
Predicting Amino Acid Preferences in the Complementarity Determining Regions of an Antibody-Antigen Recognition Interface
分子名称: sc-dsFv derived from the G6-Fab
著者Yu, C.M, Peng, H.P, Chen, I.C, Lee, Y.C, Chen, J.B, Tsai, K.C, Chen, C.T, Chang, J.Y, Yang, E.W, Hsu, P.C, Jian, J.W, Hsu, H.J, Chang, H.J, Hsu, W.L, Huang, K.F, Ma, A.C, Yang, A.S.
登録日2011-02-16
公開日2012-02-22
最終更新日2012-04-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Rationalization and design of the complementarity determining region sequences in an antibody-antigen recognition interface
Plos One, 7, 2012
6EGC
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BU of 6egc by Molmil
Single-chain version of 2L4HC2_23 (PDB 5J0K)
分子名称: SC_2L4HC2_23
著者Bick, M.J, Chen, Z, DiMaio, F.
登録日2018-08-19
公開日2019-05-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Self-Assembling 2D Arrays with de Novo Protein Building Blocks.
J.Am.Chem.Soc., 141, 2019
6LX3
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BU of 6lx3 by Molmil
Cryo-EM structure of human secretory immunoglobulin A
分子名称: Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor
著者Wang, Y, Wang, G, Li, Y, Xiao, J.
登録日2020-02-10
公開日2020-05-27
最終更新日2020-07-22
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
2OCW
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BU of 2ocw by Molmil
Solution structure of human secretory component
分子名称: Polymeric-immunoglobulin receptor
著者Bonner, A, Perrier, C, Corthesy, B, Perkins, S.J.
登録日2006-12-21
公開日2007-04-10
最終更新日2023-12-27
実験手法SOLUTION SCATTERING
主引用文献Solution structure of human secretory component and implications for biological function.
J.Biol.Chem., 282, 2007
1D97
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BU of 1d97 by Molmil
CHIRAL PHOSPHOROTHIOATE ANALOGUES OF B-DNA: THE CRYSTAL STRUCTURE OF RP-D(GP(S) CPGP(S)CPGP(S)C)
分子名称: DNA (5'-D(RP*GP*(SC)P*GP*(SC)P*GP*(SC))-3')
著者Cruse, W.B.T, Salisbury, S.A, Brown, T, Cosstick, R, Eckstein, F, Kennard, O.
登録日1992-10-17
公開日1993-07-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Chiral phosphorothioate analogues of B-DNA. The crystal structure of Rp-d[Gp(S)CpGp(S)CpGp(S)C].
J.Mol.Biol., 192, 1986
6DTI
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BU of 6dti by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an unmodifed anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin
分子名称: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Cantara, W.A, DeMirci, H, Agris, P.F.
登録日2018-06-16
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.54 Å)
主引用文献A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
6VRD
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BU of 6vrd by Molmil
Crystal structure of RNase H/RNA/PS-ASO complex at an atomic level
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, RNA (5'-R(*(OMC)P*(N7X)P*(T39)P*(C5L)P*(A2M))-D(P*(SC)P*(PST)P*(SC)P*(AS)P*(SC)P*(SC)P*(SC)P*(AS)P*(SC)P*(PST))-R(P*(6OO)P*(RFJ)P*(6OO)P*(6OO)P*(6NW))-3'), ...
著者Cho, Y.-J, Butler, D.
登録日2020-02-07
公開日2021-02-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.299 Å)
主引用文献Crystal structure of RNase H/RNA/PS-ASO complex at an atomic level
To Be Published
2K65
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BU of 2k65 by Molmil
NMR solution structure of the exon/intron binding site 1 (EBS1/IBS1) of the group II intron Sc.ai5(gamma)
分子名称: 5'-R(*CP*AP*GP*UP*GP*UP*C)-3', 5'-R(*GP*GP*CP*AP*CP*UP*G)-3'
著者Kruschel, D, Sigel, R.K.O.
登録日2008-07-04
公開日2009-07-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the 5'-splice site of a group II intron ribozyme
To be Published
6T0B
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BU of 6t0b by Molmil
The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CALCIUM ION, CARDIOLIPIN, ...
著者Marechal, A, Pinotsis, N, Hartley, A.
登録日2019-10-02
公開日2020-04-22
最終更新日2020-05-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes.
Proc.Natl.Acad.Sci.USA, 117, 2020
8SWB
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BU of 8swb by Molmil
RNase H complex with streopure ASO and RNA
分子名称: DI(HYDROXYETHYL)ETHER, DNA (5'-R(*(OMC)P*(N7X)P*(T39)P*(C5L)P*(A2M))-D(P*(SC)P*(PST)P*(SC)P*AP*(SC)P*(SC)P*(RC)P*(AS)P*(SC)P*(PST))-R(P*(6OO)P*(RFJ)P*(6OO)P*(6OO)P*(6NW))-3'), GLYCEROL, ...
著者Cho, Y.-J, Iwamoto, N.
登録日2023-05-18
公開日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of RNase H/RNA/PS-ASO complex at an atomic level
To Be Published
6MPI
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BU of 6mpi by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGU-codon in the A-site and paromomycin
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Cantara, W.A, DeMirci, H, Agris, P.F.
登録日2018-10-07
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
6MKN
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BU of 6mkn by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Cantara, W.A, DeMirci, H, Agris, P.F.
登録日2018-09-25
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
6MPF
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BU of 6mpf by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGC-codon in the A-site and paromomycin
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Cantara, W.A, DeMirci, H, Agris, P.F.
登録日2018-10-05
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
6U6X
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BU of 6u6x by Molmil
Human SAMHD1 bound to deoxyribo(C*G*C*C*T)-oligonucleotide
分子名称: DNA SC-GS-SC-SC-DT, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION
著者Taylor, A.B, Bhattacharya, A, Wang, Z, Ivanov, D.N.
登録日2019-08-30
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification.
Nat Commun, 12, 2021
3LN1
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Structure of celecoxib bound at the COX-2 active site
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE, ...
著者Kiefer, J.R, Kurumbail, R.G, Stallings, W.C, Pawlitz, J.L.
登録日2010-02-01
公開日2010-10-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life.
Bioorg.Med.Chem.Lett., 20, 2010
6HU9
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BU of 6hu9 by Molmil
III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, CALCIUM ION, ...
著者Hartley, A.M, Pinotsis, N, Marechal, A.
登録日2018-10-05
公開日2018-12-26
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structure of yeast cytochrome c oxidase in a supercomplex with cytochrome bc1.
Nat. Struct. Mol. Biol., 26, 2019
6Q9E
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Complex III2 focused refinement from Ovine respiratory supercomplex I+III2
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CARDIOLIPIN, Cytochrome b, ...
著者Letts, J.A, Sazanov, L.A.
登録日2018-12-18
公開日2019-08-21
最終更新日2019-10-02
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019

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