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2D07
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BU of 2d07 by Molmil
Crystal Structure of SUMO-3-modified Thymine-DNA Glycosylase
分子名称: G/T mismatch-specific thymine DNA glycosylase, Ubiquitin-like protein SMT3B
著者Baba, D, Maita, N, Jee, J.G, Uchimura, Y, Saitoh, H, Sugasawa, K, Hanaoka, F, Tochio, H, Hiroaki, H, Shirakawa, M.
登録日2005-07-26
公開日2006-06-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of SUMO-3-modified Thymine-DNA Glycosylase
J.Mol.Biol., 359, 2006
2IO3
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BU of 2io3 by Molmil
Crystal structure of human Senp2 in complex with RanGAP1-SUMO-2
分子名称: Ran GTPase-activating protein 1, Sentrin-specific protease 2, Small ubiquitin-related modifier 2
著者Reverter, D, Lima, C.D.
登録日2006-10-09
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates.
Nat.Struct.Mol.Biol., 13, 2006
2AWT
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BU of 2awt by Molmil
Solution Structure of Human Small Ubiquitin-Like Modifier Protein Isoform 2 (SUMO-2)
分子名称: Small ubiquitin-related modifier 2
著者Chang, C.K, Wang, Y.H, Chung, T.L, Chang, C.F, Li, S.S.L, Huang, T.H.
登録日2005-09-02
公開日2006-10-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of Human Small Ubiquitin-Like Modifier Protein Isoform 2 (SUMO-2)
To be Published
3UIP
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BU of 3uip by Molmil
Complex between human RanGAP1-SUMO1, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II
分子名称: E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ...
著者Gareau, J.R, Reverter, D, Lima, C.D.
登録日2011-11-05
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.293 Å)
主引用文献Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2.
J.Biol.Chem., 287, 2012
2LAS
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BU of 2las by Molmil
Molecular Determinants of Paralogue-Specific SUMO-SIM Recognition
分子名称: M-IR2_peptide, Small ubiquitin-related modifier 1
著者Namanja, A, Li, Y, Su, Y, Wong, S, Lu, J, Colson, L, Wu, C, Li, S, Chen, Y.
登録日2011-03-20
公開日2011-12-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Insights into High Affinity Small Ubiquitin-like Modifier (SUMO) Recognition by SUMO-interacting Motifs (SIMs) Revealed by a Combination of NMR and Peptide Array Analysis.
J.Biol.Chem., 287, 2012
2IO0
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BU of 2io0 by Molmil
Crystal structure of human Senp2 in complex with preSUMO-2
分子名称: SULFATE ION, Sentrin-specific protease 2, Small ubiquitin-related modifier 2 precursor
著者Reverter, D, Lima, C.D.
登録日2006-10-09
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates.
Nat.Struct.Mol.Biol., 13, 2006
4BKG
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BU of 4bkg by Molmil
crystal structure of human diSUMO-2
分子名称: SMALL UBIQUITIN-RELATED MODIFIER 2
著者Keusekotten, K, Bade, V.N, Meyer-Teschendorf, K, Sriramachandran, A, Fischer-Schrader, K, Krause, A, Horst, C, Hofmann, K, Dohmen, R.J, Praefcke, G.J.K.
登録日2013-04-25
公開日2013-11-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Multivalent Interactions of the Sumo-Interaction Motifs in the Ring-Finger Protein 4 (Rnf4) Determine the Specificity for Chains of the Small Ubiquitin-Related Modifier (Sumo).
Biochem.J., 457, 2014
6K5R
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BU of 6k5r by Molmil
Complex of SUMO2 with Phosphorylated viral SIM IE2
分子名称: ASP-THR-ALA-GLY-CYS-ILE-VAL-ILE-SEP-ASP-SEP-GLU, Small ubiquitin-related modifier 3
著者Chatterjee, K.S, Das, R.
登録日2019-05-30
公開日2019-08-07
最終更新日2019-12-25
実験手法SOLUTION NMR
主引用文献Casein kinase-2-mediated phosphorylation increases the SUMO-dependent activity of the cytomegalovirus transactivator IE2.
J.Biol.Chem., 294, 2019
7ZJU
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BU of 7zju by Molmil
Structure of human USPL1 in covalent complex with SUMO3-2Br probe
分子名称: 2-bromanylethanamine, CALCIUM ION, CHLORIDE ION, ...
著者Zhao, Z, Gersch, M.
登録日2022-04-12
公開日2023-09-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Native Semisynthesis of Isopeptide-Linked Substrates for Specificity Analysis of Deubiquitinases and Ubl Proteases.
J.Am.Chem.Soc., 145, 2023
3KYD
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BU of 3kyd by Molmil
Human SUMO E1~SUMO1-AMP tetrahedral intermediate mimic
分子名称: 1,2-ETHANEDIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, SUMO-activating enzyme subunit 1, ...
著者Lima, C.D.
登録日2009-12-05
公開日2010-02-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Active site remodelling accompanies thioester bond formation in the SUMO E1.
Nature, 463, 2010
7AAV
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BU of 7aav by Molmil
Human pre-Bact-2 spliceosome core structure
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ...
著者Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
登録日2020-09-04
公開日2020-12-09
最終更新日2020-12-30
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
8ITY
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BU of 8ity by Molmil
human RNA polymerase III pre-initiation complex closed DNA 1
分子名称: DNA (82-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
著者Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y.
登録日2023-03-23
公開日2023-06-07
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure of the SNAPc-bound RNA polymerase III preinitiation complex.
Cell Res., 33, 2023
7A6H
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BU of 7a6h by Molmil
Cryo-EM structure of human apo RNA Polymerase III
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W.
登録日2020-08-25
公開日2021-02-03
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states.
Nat.Struct.Mol.Biol., 28, 2021
6OM0
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BU of 6om0 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-17
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLE
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BU of 6ole by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
8IUH
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BU of 8iuh by Molmil
RNA polymerase III pre-initiation complex open complex 1
分子名称: DNA (81-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
著者Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y.
登録日2023-03-24
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of the SNAPc-bound RNA polymerase III preinitiation complex.
Cell Res., 33, 2023
7ONB
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BU of 7onb by Molmil
Structure of the U2 5' module of the A3'-SSA complex
分子名称: MINX, PHD finger-like domain-containing protein 5A, RNU2, ...
著者Cretu, C, Pena, V.
登録日2021-05-25
公開日2021-08-04
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
Nat Commun, 12, 2021
4V6X
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BU of 4v6x by Molmil
Structure of the human 80S ribosome
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R.
登録日2013-02-27
公開日2014-07-09
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structures of the human and Drosophila 80S ribosome.
Nature, 497, 2013
6JXV
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BU of 6jxv by Molmil
SUMO1 bound to phosphorylated SLS4-SIM peptide from ICP0
分子名称: Phosphorylated SLS4-SIM from ubiquitin E3 ligase ICP0, Small ubiquitin-related modifier
著者Hembram, D.S.S, Negi, H, Shet, D, Das, R.
登録日2019-04-25
公開日2020-02-05
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2.
J.Mol.Biol., 432, 2020
6JXU
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BU of 6jxu by Molmil
SUMO1 bound to SLS4-SIM peptide from ICP0
分子名称: Small ubiquitin-related modifier, viral protein
著者Hembram, D.S.S, Negi, H, Shet, D, Das, R.
登録日2019-04-25
公開日2020-02-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2.
J.Mol.Biol., 432, 2020
5WWF
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BU of 5wwf by Molmil
Crystal structure of hnRNPA2B1 in complex with RNA
分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA
著者Wu, B.X, Su, S.C, Ma, J.B.
登録日2017-01-01
公開日2018-01-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
5EN1
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BU of 5en1 by Molmil
Crystal structure of hnRNPA2B1 in complex with RNA
分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*AP*CP*UP*G)-3')
著者Wu, B.X, Su, S.C, Ma, J.B.
登録日2015-11-09
公開日2016-11-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1
Nat Commun, 2018
3KYC
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BU of 3kyc by Molmil
Human SUMO E1 complex with a SUMO1-AMP mimic
分子名称: 5'-deoxy-5'-(sulfamoylamino)adenosine, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ...
著者Lima, C.D.
登録日2009-12-05
公開日2010-02-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Active site remodelling accompanies thioester bond formation in the SUMO E1.
Nature, 463, 2010
8IUE
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BU of 8iue by Molmil
RNA polymerase III pre-initiation complex melting complex 1
分子名称: DNA (74-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
著者Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y.
登録日2023-03-24
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure of the SNAPc-bound RNA polymerase III preinitiation complex.
Cell Res., 33, 2023
6ZY7
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BU of 6zy7 by Molmil
Cryo-EM structure of the entire Human topoisomerase II alpha in State 1
分子名称: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ...
著者Vanden Broeck, A, Lamour, V.
登録日2020-07-30
公開日2021-05-26
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.64 Å)
主引用文献Structural basis for allosteric regulation of Human Topoisomerase II alpha.
Nat Commun, 12, 2021

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