PDB: 103 件ウェブページステータス検索Chemie searchBIRD

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2D11	Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide 分子名称: Na(+)/H(+) exchange regulatory cofactor NHE-RF2, Radixin 著者 Terawaki, S, Maesaki, R, Hakoshima, T. 登録日 2005-08-11 公開日 2006-07-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Structural basis for NHERF recognition by ERM proteins Structure, 14, 2006
6TXS	The structure of the FERM domain and helical linker of human moesin bound to a CD44 peptide 分子名称: CD44 antigen, Moesin 著者 Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2020-01-14 公開日 2020-01-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
6TXQ	The high resolution structure of the FERM domain and helical linker of human moesin 分子名称: ACETATE ION, Moesin 著者 Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2020-01-14 公開日 2020-01-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
6U4K	Human talin2 residues 1-403 分子名称: Talin-2 著者 Izard, T, Rangarajan, E.S, Colgan, L, Yasuda, R, Chinthalapudi, K. 登録日 2019-08-26 公開日 2020-07-08 最終更新日 2020-09-23 実験手法 X-RAY DIFFRACTION (2.555 Å) 主引用文献 A distinct talin2 structure directs isoform specificity in cell adhesion. J.Biol.Chem., 295, 2020
4RM8	Crystal structure of human ezrin in space group P21 分子名称: Ezrin 著者 Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G. 登録日 2014-10-20 公開日 2015-12-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin. Biochem. J., 473, 2016
4RMA	Crystal structure of the FERM domain of human ezrin 分子名称: Ezrin, SULFATE ION 著者 Phang, J.M, Harrop, S.J, Duff, A.P, Wilk, K.E, Curmi, P.M.G. 登録日 2014-10-21 公開日 2015-12-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin. Biochem. J., 473, 2016
4RM9	Crystal structure of human ezrin in space group C2221 分子名称: Ezrin 著者 Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G. 登録日 2014-10-21 公開日 2015-12-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin. Biochem. J., 473, 2016
4YL8	Crystal structure of the Crumbs/Moesin complex 分子名称: GLYCEROL, IODIDE ION, Moesin, ... 著者 Wei, Z, Li, Y, Zhang, M. 登録日 2015-03-05 公開日 2015-04-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Basis for the Phosphorylation-regulated Interaction between the Cytoplasmic Tail of Cell Polarity Protein Crumbs and the Actin-binding Protein Moesin J.Biol.Chem., 290, 2015
4ZRK	Merlin-FERM and Lats1 complex 分子名称: Merlin, Serine/threonine-protein kinase LATS1 著者 Lin, Z, Li, Y, Wei, Z, Zhang, M. 登録日 2015-05-12 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.316 Å) 主引用文献 Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
4ZRI	Crystal structure of Merlin-FERM and Lats2 分子名称: Merlin, Serine/threonine-protein kinase LATS2 著者 Li, F, Zhou, H, Long, J, Shen, Y. 登録日 2015-05-12 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
4ZRJ	Structure of Merlin-FERM and CTD 分子名称: GLYCEROL, Merlin 著者 Lin, Z, Li, F, Long, J, Shen, Y. 登録日 2015-05-12 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
8CIS	The FERM domain of human moesin with two bound peptides identified by phage display 分子名称: 1,2-ETHANEDIOL, ACETATE ION, C3P, ... 著者 Bradshaw, W.J, Katis, V.L, Leisner, T.M, Fairhead, M, Bountra, C, von Delft, F, Pearce, K.H, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
8CIU	The FERM domain of human moesin mutant H288A 分子名称: Moesin 著者 Bradshaw, W.J, Katis, V.L, Koekemoer, L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.393 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
8CIT	The FERM domain of human moesin mutant L281R 分子名称: Moesin 著者 Bradshaw, W.J, Katis, V.L, Koekemoer, L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.536 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
8CIR	The FERM domain of human moesin with a bound peptide identified by phage display 分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, ... 著者 Bradshaw, W.J, Katis, V.L, Leisner, T.M, Fairhead, M, Bountra, C, von Delft, F, Pearce, K.H, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
1GG3	CRYSTAL STRUCTURE OF THE PROTEIN 4.1R MEMBRANE BINDING DOMAIN 分子名称: ERYTHROID MEMBRANE PROTEIN 4.1R 著者 Han, B.G. 登録日 2000-07-11 公開日 2001-01-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization. Nat.Struct.Biol., 7, 2000
2EMS	Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule CD43 分子名称: Leukosialin, Radixin 著者 Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T. 登録日 2007-03-28 公開日 2008-04-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins J.Mol.Biol., 381, 2008
1H4R	Crystal Structure of the FERM domain of Merlin, the Neurofibromatosis 2 Tumor Suppressor Protein. 分子名称: MERLIN, SULFATE ION 著者 Cooper, D.R, Kang, B.S, Sheffield, P, Devedjiev, Y, Derewenda, Z.S. 登録日 2001-05-14 公開日 2002-01-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product. Acta Crystallogr.,Sect.D, 58, 2002
2EMT	Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule PSGL-1 分子名称: P-selectin glycoprotein ligand 1, Radixin 著者 Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T. 登録日 2007-03-28 公開日 2008-03-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of PSGL-1 binding to ERM proteins Genes Cells, 12, 2007
1GC7	CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN 分子名称: RADIXIN 著者 Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T. 登録日 2000-07-21 公開日 2000-09-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J., 19, 2000
1GC6	CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE 分子名称: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, RADIXIN 著者 Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T. 登録日 2000-07-21 公開日 2000-09-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J., 19, 2000
1J19	Crystal structure of the radxin FERM domain complexed with the ICAM-2 cytoplasmic peptide 分子名称: 16-mer peptide from Intercellular adhesion molecule-2, radixin 著者 Hamada, K, Shimizu, T, Yonemura, S, Tsukita, S, Tsukita, S, Hakoshima, T. 登録日 2002-12-02 公開日 2003-03-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex EMBO J., 22, 2003
1ISN	Crystal structure of merlin FERM domain 分子名称: merlin 著者 Shimizu, T, Seto, A, Maita, N, Hamada, K, Tsukita, S, Tsukita, S, Hakoshima, T. 登録日 2001-12-13 公開日 2002-04-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain. J.Biol.Chem., 277, 2002
2HE7	FERM domain of EPB41L3 (DAL-1) 分子名称: Band 4.1-like protein 3 著者 Hallberg, B.M, Busam, R.D, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Schiavone, L.H, Johansson, I, Hogbom, M, Karlberg, T, Kotenyova, T, Nilvebrandt, J, Norberg, P, Stenmark, P, Nordlund, P, Nilsson-ehle, P, Nyman, T, Ogg, D, Sagemark, J, Sundstrom, M, Uppenberg, J, Van den berg, S, Weigelt, J, Persson, C, Thorsell, A.G, Structural Genomics Consortium (SGC) 登録日 2006-06-21 公開日 2006-07-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B). J.Biol.Chem., 286, 2011
2D2Q	Crystal structure of the dimerized radixin FERM domain 分子名称: Radixin 著者 Kitano, K, Yusa, F, Hakoshima, T. 登録日 2005-09-15 公開日 2006-04-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295-304 ACTA CRYSTALLOGR.,SECT.F, 62, 2006

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