2D11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2d11 by Molmil](/molmil-images/mine/2d11) | |
6TXS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6txs by Molmil](/molmil-images/mine/6txs) | The structure of the FERM domain and helical linker of human moesin bound to a CD44 peptide | 分子名称: | CD44 antigen, Moesin | 著者 | Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2020-01-14 | 公開日 | 2020-01-29 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
|
|
6TXQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6txq by Molmil](/molmil-images/mine/6txq) | The high resolution structure of the FERM domain and helical linker of human moesin | 分子名称: | ACETATE ION, Moesin | 著者 | Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2020-01-14 | 公開日 | 2020-01-29 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
|
|
6U4K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u4k by Molmil](/molmil-images/mine/6u4k) | Human talin2 residues 1-403 | 分子名称: | Talin-2 | 著者 | Izard, T, Rangarajan, E.S, Colgan, L, Yasuda, R, Chinthalapudi, K. | 登録日 | 2019-08-26 | 公開日 | 2020-07-08 | 最終更新日 | 2020-09-23 | 実験手法 | X-RAY DIFFRACTION (2.555 Å) | 主引用文献 | A distinct talin2 structure directs isoform specificity in cell adhesion. J.Biol.Chem., 295, 2020
|
|
4RM8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rm8 by Molmil](/molmil-images/mine/4rm8) | Crystal structure of human ezrin in space group P21 | 分子名称: | Ezrin | 著者 | Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G. | 登録日 | 2014-10-20 | 公開日 | 2015-12-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin. Biochem. J., 473, 2016
|
|
4RMA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rma by Molmil](/molmil-images/mine/4rma) | Crystal structure of the FERM domain of human ezrin | 分子名称: | Ezrin, SULFATE ION | 著者 | Phang, J.M, Harrop, S.J, Duff, A.P, Wilk, K.E, Curmi, P.M.G. | 登録日 | 2014-10-21 | 公開日 | 2015-12-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin. Biochem. J., 473, 2016
|
|
4RM9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rm9 by Molmil](/molmil-images/mine/4rm9) | Crystal structure of human ezrin in space group C2221 | 分子名称: | Ezrin | 著者 | Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G. | 登録日 | 2014-10-21 | 公開日 | 2015-12-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin. Biochem. J., 473, 2016
|
|
4YL8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yl8 by Molmil](/molmil-images/mine/4yl8) | Crystal structure of the Crumbs/Moesin complex | 分子名称: | GLYCEROL, IODIDE ION, Moesin, ... | 著者 | Wei, Z, Li, Y, Zhang, M. | 登録日 | 2015-03-05 | 公開日 | 2015-04-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Basis for the Phosphorylation-regulated Interaction between the Cytoplasmic Tail of Cell Polarity Protein Crumbs and the Actin-binding Protein Moesin J.Biol.Chem., 290, 2015
|
|
4ZRK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zrk by Molmil](/molmil-images/mine/4zrk) | Merlin-FERM and Lats1 complex | 分子名称: | Merlin, Serine/threonine-protein kinase LATS1 | 著者 | Lin, Z, Li, Y, Wei, Z, Zhang, M. | 登録日 | 2015-05-12 | 公開日 | 2015-06-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.316 Å) | 主引用文献 | Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
|
|
4ZRI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zri by Molmil](/molmil-images/mine/4zri) | Crystal structure of Merlin-FERM and Lats2 | 分子名称: | Merlin, Serine/threonine-protein kinase LATS2 | 著者 | Li, F, Zhou, H, Long, J, Shen, Y. | 登録日 | 2015-05-12 | 公開日 | 2015-06-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
|
|
4ZRJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zrj by Molmil](/molmil-images/mine/4zrj) | Structure of Merlin-FERM and CTD | 分子名称: | GLYCEROL, Merlin | 著者 | Lin, Z, Li, F, Long, J, Shen, Y. | 登録日 | 2015-05-12 | 公開日 | 2015-06-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
|
|
8CIS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cis by Molmil](/molmil-images/mine/8cis) | The FERM domain of human moesin with two bound peptides identified by phage display | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, C3P, ... | 著者 | Bradshaw, W.J, Katis, V.L, Leisner, T.M, Fairhead, M, Bountra, C, von Delft, F, Pearce, K.H, Brennan, P.E. | 登録日 | 2023-02-10 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
|
|
8CIU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ciu by Molmil](/molmil-images/mine/8ciu) | The FERM domain of human moesin mutant H288A | 分子名称: | Moesin | 著者 | Bradshaw, W.J, Katis, V.L, Koekemoer, L, Bountra, C, von Delft, F, Brennan, P.E. | 登録日 | 2023-02-10 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.393 Å) | 主引用文献 | Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
|
|
8CIT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cit by Molmil](/molmil-images/mine/8cit) | The FERM domain of human moesin mutant L281R | 分子名称: | Moesin | 著者 | Bradshaw, W.J, Katis, V.L, Koekemoer, L, Bountra, C, von Delft, F, Brennan, P.E. | 登録日 | 2023-02-10 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.536 Å) | 主引用文献 | Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
|
|
8CIR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cir by Molmil](/molmil-images/mine/8cir) | The FERM domain of human moesin with a bound peptide identified by phage display | 分子名称: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, ... | 著者 | Bradshaw, W.J, Katis, V.L, Leisner, T.M, Fairhead, M, Bountra, C, von Delft, F, Pearce, K.H, Brennan, P.E. | 登録日 | 2023-02-10 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
|
|
1GG3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1gg3 by Molmil](/molmil-images/mine/1gg3) | |
2EMS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ems by Molmil](/molmil-images/mine/2ems) | Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule CD43 | 分子名称: | Leukosialin, Radixin | 著者 | Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T. | 登録日 | 2007-03-28 | 公開日 | 2008-04-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins J.Mol.Biol., 381, 2008
|
|
1H4R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1h4r by Molmil](/molmil-images/mine/1h4r) | Crystal Structure of the FERM domain of Merlin, the Neurofibromatosis 2 Tumor Suppressor Protein. | 分子名称: | MERLIN, SULFATE ION | 著者 | Cooper, D.R, Kang, B.S, Sheffield, P, Devedjiev, Y, Derewenda, Z.S. | 登録日 | 2001-05-14 | 公開日 | 2002-01-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product. Acta Crystallogr.,Sect.D, 58, 2002
|
|
2EMT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2emt by Molmil](/molmil-images/mine/2emt) | Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule PSGL-1 | 分子名称: | P-selectin glycoprotein ligand 1, Radixin | 著者 | Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T. | 登録日 | 2007-03-28 | 公開日 | 2008-03-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of PSGL-1 binding to ERM proteins Genes Cells, 12, 2007
|
|
1GC7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1gc7 by Molmil](/molmil-images/mine/1gc7) | CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN | 分子名称: | RADIXIN | 著者 | Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T. | 登録日 | 2000-07-21 | 公開日 | 2000-09-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J., 19, 2000
|
|
1GC6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1gc6 by Molmil](/molmil-images/mine/1gc6) | CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, RADIXIN | 著者 | Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T. | 登録日 | 2000-07-21 | 公開日 | 2000-09-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J., 19, 2000
|
|
1J19
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1j19 by Molmil](/molmil-images/mine/1j19) | Crystal structure of the radxin FERM domain complexed with the ICAM-2 cytoplasmic peptide | 分子名称: | 16-mer peptide from Intercellular adhesion molecule-2, radixin | 著者 | Hamada, K, Shimizu, T, Yonemura, S, Tsukita, S, Tsukita, S, Hakoshima, T. | 登録日 | 2002-12-02 | 公開日 | 2003-03-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex EMBO J., 22, 2003
|
|
1ISN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1isn by Molmil](/molmil-images/mine/1isn) | Crystal structure of merlin FERM domain | 分子名称: | merlin | 著者 | Shimizu, T, Seto, A, Maita, N, Hamada, K, Tsukita, S, Tsukita, S, Hakoshima, T. | 登録日 | 2001-12-13 | 公開日 | 2002-04-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain. J.Biol.Chem., 277, 2002
|
|
2HE7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2he7 by Molmil](/molmil-images/mine/2he7) | FERM domain of EPB41L3 (DAL-1) | 分子名称: | Band 4.1-like protein 3 | 著者 | Hallberg, B.M, Busam, R.D, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Schiavone, L.H, Johansson, I, Hogbom, M, Karlberg, T, Kotenyova, T, Nilvebrandt, J, Norberg, P, Stenmark, P, Nordlund, P, Nilsson-ehle, P, Nyman, T, Ogg, D, Sagemark, J, Sundstrom, M, Uppenberg, J, Van den berg, S, Weigelt, J, Persson, C, Thorsell, A.G, Structural Genomics Consortium (SGC) | 登録日 | 2006-06-21 | 公開日 | 2006-07-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B). J.Biol.Chem., 286, 2011
|
|
2D2Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2d2q by Molmil](/molmil-images/mine/2d2q) | |