8FD6
| Engineered human dynein motor domain in the microtubule-unbound state in the buffer containing ATP-Vi | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, ... | 著者 | Ton, W, Wang, Y, Chai, P. | 登録日 | 2022-12-02 | 公開日 | 2023-06-21 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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8FDU
| Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi (local refined on AAA3-AAA5 and LIS1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, Platelet-activating factor acetylhydrolase IB subunit beta,Platelet-activating factor acetylhydrolase IB subunit beta,human LIS1 protein with a SNAP tag | 著者 | Ton, W, Wang, Y, Chai, P. | 登録日 | 2022-12-04 | 公開日 | 2023-06-21 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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8GLV
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3VKG
| X-ray structure of an MTBD truncation mutant of dynein motor domain | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Dynein heavy chain, cytoplasmic, ... | 著者 | Kon, T, Oyama, T, Shimo-Kon, R, Suto, K, Kurisu, G. | 登録日 | 2011-11-16 | 公開日 | 2012-03-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | The 2.8 A crystal structure of the dynein motor domain Nature, 484, 2012
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3VKH
| X-ray structure of a functional full-length dynein motor domain | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Dynein heavy chain, cytoplasmic | 著者 | Kon, T, Oyama, T, Shimo-Kon, R, Suto, K, Kurisu, G. | 登録日 | 2011-11-16 | 公開日 | 2012-03-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | The 2.8 A crystal structure of the dynein motor domain Nature, 484, 2012
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7MOQ
| The structure of the Tetrahymena thermophila outer dynein arm on doublet microtubule | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Docking complex 1 protein, ... | 著者 | Kubo, S, Yang, S.K, Ichikawa, M, Bui, K.H. | 登録日 | 2021-05-03 | 公開日 | 2021-07-14 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | Remodeling and activation mechanisms of outer arm dyneins revealed by cryo-EM. Embo Rep., 22, 2021
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7MGM
| Structure of yeast cytoplasmic dynein with AAA3 Walker B mutation bound to Lis1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Lahiri, I, Reimer, J.M, Leschziner, A.E. | 登録日 | 2021-04-12 | 公開日 | 2022-01-19 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for cytoplasmic dynein-1 regulation by Lis1. Elife, 11, 2022
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7KEK
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7K5B
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7K58
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7KZM
| Outer dynein arm bound to doublet microtubules from C. reinhardtii | 分子名称: | DC1, DC2, Dynein 11 kDa light chain, ... | 著者 | Walton, T, Wu, H, Brown, A.B. | 登録日 | 2020-12-10 | 公開日 | 2021-01-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | 主引用文献 | Structure of a microtubule-bound axonemal dynein. Nat Commun, 12, 2021
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7MI8
| Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 5 | 分子名称: | Fusion protein of Dynein and Endolysin | 著者 | Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M. | 登録日 | 2021-04-16 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28, 2021
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7MI3
| Signal subtracted reconstruction of AAA2, AAA3, and AAA4 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 4 | 分子名称: | (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ... | 著者 | Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M. | 登録日 | 2021-04-16 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28, 2021
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7MI1
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7MI6
| Yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound, Model 1 | 分子名称: | (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ... | 著者 | Santarossa, C.C, Urnavicius, L, Coudray, N, Ekeirt, D.C, Bhabha, G, Kapoor, T.M. | 登録日 | 2021-04-16 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28, 2021
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7KZO
| Outer dynein arm docking complex bound to doublet microtubules from C. reinhardtii | 分子名称: | Dynein gamma chain, flagellar outer arm, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Walton, T, Wu, H, Brown, A.B. | 登録日 | 2020-12-10 | 公開日 | 2021-01-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of a microtubule-bound axonemal dynein. Nat Commun, 12, 2021
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7KZN
| Outer dynein arm core subcomplex from C. reinhardtii | 分子名称: | DC1, DC2, Dynein 11 kDa light chain, ... | 著者 | Walton, T, Wu, H, Brown, A.B. | 登録日 | 2020-12-10 | 公開日 | 2021-01-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure of a microtubule-bound axonemal dynein. Nat Commun, 12, 2021
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4AKH
| Dynein Motor Domain - AMPPNP complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, DYNEIN HEAVY CHAIN CYTOPLASMIC, ... | 著者 | Schmidt, H, Gleave, E.S, Carter, A.P. | 登録日 | 2012-02-22 | 公開日 | 2012-03-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure Nat.Struct.Mol.Biol., 19, 2012
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4AKG
| Dynein Motor Domain - ATP complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, ... | 著者 | Schmidt, H, Gleave, E.S, Carter, A.P. | 登録日 | 2012-02-22 | 公開日 | 2012-03-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure Nat.Struct.Mol.Biol., 19, 2012
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4AKI
| Dynein Motor Domain - LuAc derivative | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, DYNEIN HEAVY CHAIN CYTOPLASMIC, ... | 著者 | Schmidt, H, Gleave, E.S, Carter, A.P. | 登録日 | 2012-02-22 | 公開日 | 2012-03-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure Nat.Struct.Mol.Biol., 19, 2012
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4AI6
| Dynein Motor Domain - ADP complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, ... | 著者 | Schmidt, H, Gleave, E.S, Carter, A.P. | 登録日 | 2012-02-08 | 公開日 | 2012-03-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure Nat.Struct.Mol.Biol., 19, 2012
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7Z8L
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7Z8G
| Cytoplasmic dynein-1 motor domain | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | 著者 | Chaaban, S, Carter, A.P. | 登録日 | 2022-03-17 | 公開日 | 2022-07-27 | 最終更新日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Nature, 610, 2022
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7Z8J
| Cytoplasmic dynein (A2) bound to BICDR1 | 分子名称: | BICD family-like cargo adapter 1, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ... | 著者 | Chaaban, S, Carter, A.P. | 登録日 | 2022-03-17 | 公開日 | 2022-07-27 | 最終更新日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Nature, 610, 2022
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7Z8H
| Cytoplasmic dynein-1 motor domain AAA1, AAA2, and AAA3 subunits | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | 著者 | Chaaban, S, Carter, A.P. | 登録日 | 2022-03-17 | 公開日 | 2022-07-27 | 最終更新日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Nature, 610, 2022
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