8FD6
Engineered human dynein motor domain in the microtubule-unbound state in the buffer containing ATP-Vi
Summary for 8FD6
Entry DOI | 10.2210/pdb8fd6/pdb |
EMDB information | 29003 |
Descriptor | Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, ADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | dynein, motor domain, microtubule-unbound, motor protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 359387.15 |
Authors | |
Primary citation | Ton, W.D.,Wang, Y.,Chai, P.,Beauchamp-Perez, C.,Flint, N.T.,Lammers, L.G.,Xiong, H.,Zhang, K.,Markus, S.M. Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30:1365-1379, 2023 Cited by PubMed: 37322240DOI: 10.1038/s41594-023-01010-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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