8FD6

Engineered human dynein motor domain in the microtubule-unbound state in the buffer containing ATP-Vi

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0007018	biological_process	microtubule-based movement
A	0008569	molecular_function	minus-end-directed microtubule motor activity
A	0030286	cellular_component	dynein complex
A	0045505	molecular_function	dynein intermediate chain binding
A	0051959	molecular_function	dynein light intermediate chain binding

Functional Information from PROSITE/UniProt

site_id	PS00639
Number of Residues	11
Details	THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. INHGLMMVGPS

Chain	Residue	Details
A	ILE761-SER771

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	GLY451
A	GLY769
A	GLY1140
A	GLY1482

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS1958
A	LYS2761

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER2640

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	THR2844

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER2846

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