1EXQ
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![BU of 1exq by Molmil](/molmil-images/mine/1exq) | CRYSTAL STRUCTURE OF THE HIV-1 INTEGRASE CATALYTIC CORE DOMAIN | 分子名称: | CADMIUM ION, CHLORIDE ION, POL POLYPROTEIN, ... | 著者 | Chen, J.C.-H, Krucinski, J, Miercke, L.J.W, Finer-Moore, J.S, Tang, A.H, Leavitt, A.D, Stroud, R.M. | 登録日 | 2000-05-03 | 公開日 | 2000-11-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: a model for viral DNA binding. Proc.Natl.Acad.Sci.USA, 97, 2000
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8WF7
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![BU of 8wf7 by Molmil](/molmil-images/mine/8wf7) | The Crystal Structure of integrase from Biortus | 分子名称: | ACETATE ION, Integrase, SULFATE ION | 著者 | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | 登録日 | 2023-09-19 | 公開日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The Crystal Structure of integrase from Biortus To Be Published
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2X74
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![BU of 2x74 by Molmil](/molmil-images/mine/2x74) | Human foamy virus integrase - catalytic core. | 分子名称: | INTEGRASE | 著者 | Rety, S, Delelis, O, Rezabkova, L, Dubanchet, B, Legrand, P, Silhan, J, Lewit-Bentley, A. | 登録日 | 2010-02-23 | 公開日 | 2010-08-11 | 最終更新日 | 2012-04-18 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Structural Studies of the Catalytic Core of the Primate Foamy Virus (Pfv-1) Integrase Acta Crystallogr.,Sect.F, 66, 2010
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8S9Q
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![BU of 8s9q by Molmil](/molmil-images/mine/8s9q) | |
2X78
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![BU of 2x78 by Molmil](/molmil-images/mine/2x78) | Human foamy virus integrase - catalytic core. | 分子名称: | INTEGRASE | 著者 | Rety, S, Delelis, O, Rezabkova, L, Dubanchet, B, Legrand, P, Silhan, J, Lewit-Bentley, A. | 登録日 | 2010-02-24 | 公開日 | 2010-08-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Studies of the Catalytic Core of the Primate Foamy Virus (Pfv-1) Integrase Acta Crystallogr.,Sect.F, 66, 2010
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4GVM
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![BU of 4gvm by Molmil](/molmil-images/mine/4gvm) | |
4JLH
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![BU of 4jlh by Molmil](/molmil-images/mine/4jlh) | |
8T52
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![BU of 8t52 by Molmil](/molmil-images/mine/8t52) | |
8T5A
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![BU of 8t5a by Molmil](/molmil-images/mine/8t5a) | |
5T3A
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![BU of 5t3a by Molmil](/molmil-images/mine/5t3a) | |
2X6S
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![BU of 2x6s by Molmil](/molmil-images/mine/2x6s) | Human foamy virus integrase - catalytic core. Magnesium-bound structure. | 分子名称: | INTEGRASE, MAGNESIUM ION | 著者 | Rety, S, Delelis, O, Rezabkova, L, Dubanchet, B, Silhan, J, Lewit-Bentley, A. | 登録日 | 2010-02-19 | 公開日 | 2010-08-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structural Studies of the Catalytic Core of the Primate Foamy Virus (Pfv-1) Integrase Acta Crystallogr.,Sect.F, 66, 2010
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2X6N
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![BU of 2x6n by Molmil](/molmil-images/mine/2x6n) | Human foamy virus integrase - catalytic core. Manganese-bound structure. | 分子名称: | INTEGRASE, MANGANESE (II) ION | 著者 | Rety, S, Delelis, O, Rezabkova, L, Dubanchet, B, Silhan, J, Lewit-Bentley, A. | 登録日 | 2010-02-18 | 公開日 | 2010-08-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Structural Studies of the Catalytic Core of the Primate Foamy Virus (Pfv-1) Integrase Acta Crystallogr.,Sect.F, 66, 2010
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4ID1
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![BU of 4id1 by Molmil](/molmil-images/mine/4id1) | |
1HYV
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![BU of 1hyv by Molmil](/molmil-images/mine/1hyv) | HIV INTEGRASE CORE DOMAIN COMPLEXED WITH TETRAPHENYL ARSONIUM | 分子名称: | CHLORIDE ION, INTEGRASE, SULFATE ION, ... | 著者 | Molteni, V, Greenwald, J, Rhodes, D, Hwang, Y, Kwiatkowski, W, Bushman, F.D, Siegel, J.S, Choe, S. | 登録日 | 2001-01-22 | 公開日 | 2001-04-04 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain. Acta Crystallogr.,Sect.D, 57, 2001
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1HYZ
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![BU of 1hyz by Molmil](/molmil-images/mine/1hyz) | HIV INTEGRASE CORE DOMAIN COMPLEXED WITH A DERIVATIVE OF TETRAPHENYL ARSONIUM. | 分子名称: | (3,4-DIHYDROXY-PHENYL)-TRIPHENYL-ARSONIUM, CHLORIDE ION, INTEGRASE, ... | 著者 | Molteni, V, Greenwald, J, Rhodes, D, Hwang, Y, Kwiatkowski, W, Bushman, F.D, Siegel, J.S, Choe, S. | 登録日 | 2001-01-22 | 公開日 | 2001-04-04 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain. Acta Crystallogr.,Sect.D, 57, 2001
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5HRR
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![BU of 5hrr by Molmil](/molmil-images/mine/5hrr) | HIV Integrase Catalytic Domain containing F185K + A124N + T125S mutations complexed with GSK0002 | 分子名称: | (2S)-tert-butoxy[1-(3,4-difluorobenzyl)-6-methyl-4-(5-methyl-3,4-dihydro-2H-chromen-6-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]acetic acid, 1,2-ETHANEDIOL, CACODYLATE ION, ... | 著者 | Nolte, R.T. | 登録日 | 2016-01-24 | 公開日 | 2016-12-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase. PLoS Biol., 14, 2016
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8CBR
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![BU of 8cbr by Molmil](/molmil-images/mine/8cbr) | HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor BDM-2 | 分子名称: | (2S)-2-[3-cyclopropyl-2-(3,4-dihydro-2H-chromen-6-yl)-6-methyl-phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. | 登録日 | 2023-01-25 | 公開日 | 2023-06-07 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
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8CBU
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![BU of 8cbu by Molmil](/molmil-images/mine/8cbu) | HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT884 | 分子名称: | (2S)-2-[3-cyclopropyl-6-methyl-2-(5-methyl-3,4-dihydro-2H-chromen-6-yl)phenyl]-2-cyclopropyloxy-ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. | 登録日 | 2023-01-25 | 公開日 | 2023-06-07 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
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8CBV
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![BU of 8cbv by Molmil](/molmil-images/mine/8cbv) | HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT916 | 分子名称: | (2~{S})-2-[3-cyclopropyl-2-(8-fluoranyl-5-methyl-3,4-dihydro-2~{H}-chromen-6-yl)-6-methyl-phenyl]-2-cyclopropyloxy-ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. | 登録日 | 2023-01-25 | 公開日 | 2023-06-07 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
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8CBT
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![BU of 8cbt by Molmil](/molmil-images/mine/8cbt) | HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT872 | 分子名称: | (2~{S})-2-[3-cyclopropyl-2-(3,4-dihydro-2~{H}-chromen-6-yl)-6-methyl-phenyl]-2-cyclopropyloxy-ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. | 登録日 | 2023-01-25 | 公開日 | 2023-06-07 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
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8CBS
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![BU of 8cbs by Molmil](/molmil-images/mine/8cbs) | HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT871 | 分子名称: | (2~{S})-2-[3-cyclopropyl-6-methyl-2-(5-methyl-3,4-dihydro-2~{H}-chromen-6-yl)phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. | 登録日 | 2023-01-25 | 公開日 | 2023-06-07 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
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5HRP
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![BU of 5hrp by Molmil](/molmil-images/mine/5hrp) | HIV Integrase Catalytic Domain containing F185K + A124T mutations complexed with GSK0002 | 分子名称: | (2S)-tert-butoxy[1-(3,4-difluorobenzyl)-6-methyl-4-(5-methyl-3,4-dihydro-2H-chromen-6-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]acetic acid, 1,2-ETHANEDIOL, CACODYLATE ION, ... | 著者 | Nolte, R.T. | 登録日 | 2016-01-24 | 公開日 | 2016-12-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase. PLoS Biol., 14, 2016
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5HRS
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![BU of 5hrs by Molmil](/molmil-images/mine/5hrs) | HIV Integrase Catalytic Domain containing F185K + A124N + T125A mutations complexed with GSK0002 | 分子名称: | (2S)-tert-butoxy[1-(3,4-difluorobenzyl)-6-methyl-4-(5-methyl-3,4-dihydro-2H-chromen-6-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]acetic acid, 1,2-ETHANEDIOL, CACODYLATE ION, ... | 著者 | Nolte, R.T. | 登録日 | 2016-01-24 | 公開日 | 2016-12-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase. PLoS Biol., 14, 2016
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8A1P
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![BU of 8a1p by Molmil](/molmil-images/mine/8a1p) | HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor BI-D | 分子名称: | (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | 著者 | Singer, M.R, Pye, V.E, Cook, N.J, Cherepanov, P. | 登録日 | 2022-06-01 | 公開日 | 2023-02-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. Mbio, 14, 2023
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5HRN
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![BU of 5hrn by Molmil](/molmil-images/mine/5hrn) | HIV Integrase Catalytic Domain containing F185K mutation complexed with GSK0002 | 分子名称: | (2S)-tert-butoxy[1-(3,4-difluorobenzyl)-6-methyl-4-(5-methyl-3,4-dihydro-2H-chromen-6-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]acetic acid, 1,2-ETHANEDIOL, CACODYLATE ION, ... | 著者 | Nolte, R.T. | 登録日 | 2016-01-23 | 公開日 | 2016-12-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase. PLoS Biol., 14, 2016
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