1EXQ

CRYSTAL STRUCTURE OF THE HIV-1 INTEGRASE CATALYTIC CORE DOMAIN

Summary for 1EXQ

• Entry DOI: 10.2210/pdb1exq/pdb
• Related: 1EX4
• Descriptor: POL POLYPROTEIN, CADMIUM ION, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: hiv-1 integrase, polynucleotidyl transferase, dna-binding protein, dd35e, viral protein
• Biological source: Human immunodeficiency virus 1
• Cellular location: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P04585
• Total number of polymer chains: 2
• Total formula weight: 34370.86

Authors

Chen, J.C.-H.,Krucinski, J.,Miercke, L.J.W.,Finer-Moore, J.S.,Tang, A.H.,Leavitt, A.D.,Stroud, R.M. (deposition date: 2000-05-03, release date: 2000-11-03, Last modification date: 2024-02-07)

• Primary citation: Chen, J.C.,Krucinski, J.,Miercke, L.J.,Finer-Moore, J.S.,Tang, A.H.,Leavitt, A.D.,Stroud, R.M.; Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: a model for viral DNA binding.; Proc.Natl.Acad.Sci.USA, 97:8233-8238, 2000; PubMed: 10890912; DOI: 10.1073/pnas.150220297

Experimental method

X-RAY DIFFRACTION (1.6 Å)