1EXQ
CRYSTAL STRUCTURE OF THE HIV-1 INTEGRASE CATALYTIC CORE DOMAIN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | POL POLYPROTEIN | polymer | 154 | 16733.0 | 2 | UniProt (P04585) Pfam (PF00665) | Human immunodeficiency virus 1 | |
| 2 | C, D, G, H (A, B) | CADMIUM ION | non-polymer | 112.4 | 4 | Chemie (CD) | |||
| 3 | E, I (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | F, J, K, L (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | M, N (A, B) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A, B: 56 - 209 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Ser 56 | Cys 771 | engineered mutation |
| Asp 131 | Trp 846 | engineered mutation |
| Asp 139 | Phe 854 | engineered mutation |
| Lys 185 | Phe 900 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33466.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 904.8 | |
| All* | Total formula weight | 34370.9 |
