2EZS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ezs by Molmil](/molmil-images/mine/2ezs) | |
2EZO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ezo by Molmil](/molmil-images/mine/2ezo) | |
1DLB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dlb by Molmil](/molmil-images/mine/1dlb) | HELICAL INTERACTIONS IN THE HIV-1 GP41 CORE REVEALS STRUCTURAL BASIS FOR THE INHIBITORY ACTIVITY OF GP41 PEPTIDES | 分子名称: | HIV-1 ENVELOPE GLYCOPROTEIN GP41 | 著者 | Shu, W, Liu, J, Ji, H, Rading, L, Jiang, S, Lu, M. | 登録日 | 1999-12-09 | 公開日 | 1999-12-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Helical interactions in the HIV-1 gp41 core reveal structural basis for the inhibitory activity of gp41 peptides. Biochemistry, 39, 2000
|
|
1ENV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1env by Molmil](/molmil-images/mine/1env) | ATOMIC STRUCTURE OF THE ECTODOMAIN FROM HIV-1 GP41 | 分子名称: | HIV-1 ENVELOPE PROTEIN CHIMERA CONSISTING OF A FRAGMENT OF GCN4 ZIPPER CLONED N-TERMINAL TO TWO FRAGMENTS OF GP41 | 著者 | Weissenhorn, W, Dessen, A, Harrison, S.C, Skehel, J.J, Wiley, D.C. | 登録日 | 1997-06-27 | 公開日 | 1997-11-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Atomic structure of the ectodomain from HIV-1 gp41. Nature, 387, 1997
|
|
1F23
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f23 by Molmil](/molmil-images/mine/1f23) | CONTRIBUTION OF A BURIED HYDROGEN BOND TO HIV-1 ENVELOPE GLYCOPROTEIN STRUCTURE AND FUNCTION | 分子名称: | TRANSMEMBRANE GLYCOPROTEIN | 著者 | Liu, J, Shu, W, Fagan, M, Nunberg, J.H, Lu, M. | 登録日 | 2000-05-23 | 公開日 | 2001-06-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and functional analysis of the HIV gp41 core containing an Ile573 to Thr substitution: implications for membrane fusion. Biochemistry, 40, 2001
|
|
2EZP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ezp by Molmil](/molmil-images/mine/2ezp) | |
6NC2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nc2 by Molmil](/molmil-images/mine/6nc2) | AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody ACS202 fragment antigen binding | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC011 v4.2 SOSIP gp120, ... | 著者 | Cottrell, C.A, Ozorowski, G, Yuan, M, Copps, J, Wilson, I.A, Ward, A.B. | 登録日 | 2018-12-10 | 公開日 | 2019-06-19 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25, 2019
|
|
5HFL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hfl by Molmil](/molmil-images/mine/5hfl) | |
5HFM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hfm by Molmil](/molmil-images/mine/5hfm) | |
8E1P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e1p by Molmil](/molmil-images/mine/8e1p) | Crystal structure of BG505 SOSIP.v4.1-GT1.2 trimer in complex with gl-PGV20 and PGT124 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIP.v4.1-GT1.2gp120, ... | 著者 | Sarkar, A, Kumar, S, Wilson, I.A. | 登録日 | 2022-08-11 | 公開日 | 2023-06-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.82 Å) | 主引用文献 | Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions. Cell Rep Med, 4, 2023
|
|
7T9B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7t9b by Molmil](/molmil-images/mine/7t9b) | ApexGT5 in complex with GT5-d42.16 and RM20A3 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Berndsen, Z.T, Ward, A.B. | 登録日 | 2021-12-18 | 公開日 | 2022-09-28 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens Immunity, 2022
|
|
7T9A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7t9a by Molmil](/molmil-images/mine/7t9a) | ApexGT2 in complex with GT2-d42.16 and RM20A3 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GT2-d42.16 Fab Heavy Chain, ... | 著者 | Berndsen, Z.T, Ward, A.B. | 登録日 | 2021-12-18 | 公開日 | 2022-09-28 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens Immunity, 2022
|
|
6NC3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nc3 by Molmil](/molmil-images/mine/6nc3) | AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody VRC34 fragment antigen binding | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env AMC011 v4.2 SOSIP gp120, ... | 著者 | Cottrell, C.A, Ozorowski, G, Torres, J.L, Ward, A.B. | 登録日 | 2018-12-10 | 公開日 | 2019-06-19 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25, 2019
|
|
8T4K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t4k by Molmil](/molmil-images/mine/8t4k) | MD64 N332-GT5 SOSIP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MD64 N332-GT5 SOSIP gp120, ... | 著者 | Ozorowski, G, Torres, J.L, Ward, A.B. | 登録日 | 2023-06-09 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates. Science, 384, 2024
|
|
8SW4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sw4 by Molmil](/molmil-images/mine/8sw4) | BG505 GT1.1 SOSIP in complex with NHP Fabs 21N13, 21M20 and RM20A3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 21M20 heavy chain variable region, ... | 著者 | Ozorowski, G, Torres, J.L, Zhang, S, Ward, A.B. | 登録日 | 2023-05-17 | 公開日 | 2024-05-29 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site. Sci Immunol, 9, 2024
|
|
6UJV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ujv by Molmil](/molmil-images/mine/6ujv) | Model of the HIV-1 gp41 membrane-proximal external region, transmembrane domain and cytoplasmic tail (LLP2) | 分子名称: | Envelope glycoprotein GP41 | 著者 | Piai, A, Fu, Q, Cai, Y, Ghantous, F, Xiao, T, Shaik, M.M, Peng, H, Rits-Volloch, S, Liu, Z, Chen, W, Seaman, M.S, Chen, B, Chou, J.J. | 登録日 | 2019-10-03 | 公開日 | 2020-05-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein. Nat Commun, 11, 2020
|
|
7LXN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lxn by Molmil](/molmil-images/mine/7lxn) | Cryo-EM structure of EDC-crosslinked ConM SOSIP.v7 (ConM-EDC) in complex with bNAb PGT122 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env glycoprotein gp120, ... | 著者 | Martin, G.M, Ward, A.B, Sattentau, Q.J. | 登録日 | 2021-03-04 | 公開日 | 2022-03-09 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | 主引用文献 | Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens. Npj Vaccines, 8, 2023
|
|
7LOI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7loi by Molmil](/molmil-images/mine/7loi) | Model of the HIV-1 gp41 membrane-proximal external region, transmembrane domain and cytoplasmic tail | 分子名称: | Transmembrane protein gp41 | 著者 | Piai, A, Fu, Q, Sharp, A.K, Bighi, B, Brown, A.M, Chou, J.J. | 登録日 | 2021-02-10 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Model of the Entire Membrane-Interacting Region of the HIV-1 Fusion Protein and Its Perturbation of Membrane Morphology. J.Am.Chem.Soc., 143, 2021
|
|
5WDU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wdu by Molmil](/molmil-images/mine/5wdu) | HIV-1 Env BG505 SOSIP.664 H72C-H564C trimer in complex with bNAbs PGT122 Fab, 35O22 Fab and NIH45-46 scFv | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | 著者 | Julien, J.-P, Torrents de la Pena, A, Sanders, R.W, Wilson, I.A. | 登録日 | 2017-07-06 | 公開日 | 2018-04-04 | 最終更新日 | 2022-11-30 | 実験手法 | X-RAY DIFFRACTION (7 Å) | 主引用文献 | Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization. Cell Rep, 20, 2017
|
|
7PC2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pc2 by Molmil](/molmil-images/mine/7pc2) | HIV-1 Env (BG505 SOSIP.664) in complex with the IgA bNAb 7-269 and the antibody 3BNC117. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC IgG Fab heavy chain, ... | 著者 | Fernandez, I, Bontems, F, Pehau-Arnaudet, G, Rey, F. | 登録日 | 2021-08-03 | 公開日 | 2022-02-23 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller. J.Exp.Med., 219, 2022
|
|
4TVP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4tvp by Molmil](/molmil-images/mine/4tvp) | Crystal Structure of the HIV-1 BG505 SOSIP.664 Env Trimer Ectodomain, Comprising Atomic-Level Definition of Pre-Fusion gp120 and gp41, in Complex with Human Antibodies PGT122 and 35O22 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy chain, ... | 著者 | Pancera, M, Zhou, T, Kwong, P.D. | 登録日 | 2014-06-27 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure and immune recognition of trimeric pre-fusion HIV-1 Env. Nature, 514, 2014
|
|
9BF6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9bf6 by Molmil](/molmil-images/mine/9bf6) | |
9BER
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9ber by Molmil](/molmil-images/mine/9ber) | |
7T0O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7t0o by Molmil](/molmil-images/mine/7t0o) | |
7SQ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sq1 by Molmil](/molmil-images/mine/7sq1) | BG505.MD39TS Env trimer in complex with Fab from antibody C05 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C05 Fab Light chain, ... | 著者 | Moore, A, Du, J, Xu, Z, Walker, S, Kulp, D.W, Pallesen, J. | 登録日 | 2021-11-04 | 公開日 | 2022-06-22 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer. Nat Commun, 13, 2022
|
|