PDB: 317 件ウェブページステータス検索Chemie searchBIRD

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2EZS	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 31-40 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES 分子名称: GP41 著者 Caffrey, M, Gronenborn, A.M, Clore, G.M. 登録日 1998-05-20 公開日 1998-10-14 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41. EMBO J., 17, 1998
2EZO	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, RESTRAINED REGULARIZED MEAN STRUCTURE 分子名称: GP41 著者 Caffrey, M, Gronenborn, A.M, Clore, G.M. 登録日 1998-05-20 公開日 1998-10-14 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41. EMBO J., 17, 1998
1DLB	HELICAL INTERACTIONS IN THE HIV-1 GP41 CORE REVEALS STRUCTURAL BASIS FOR THE INHIBITORY ACTIVITY OF GP41 PEPTIDES 分子名称: HIV-1 ENVELOPE GLYCOPROTEIN GP41 著者 Shu, W, Liu, J, Ji, H, Rading, L, Jiang, S, Lu, M. 登録日 1999-12-09 公開日 1999-12-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Helical interactions in the HIV-1 gp41 core reveal structural basis for the inhibitory activity of gp41 peptides. Biochemistry, 39, 2000
1ENV	ATOMIC STRUCTURE OF THE ECTODOMAIN FROM HIV-1 GP41 分子名称: HIV-1 ENVELOPE PROTEIN CHIMERA CONSISTING OF A FRAGMENT OF GCN4 ZIPPER CLONED N-TERMINAL TO TWO FRAGMENTS OF GP41 著者 Weissenhorn, W, Dessen, A, Harrison, S.C, Skehel, J.J, Wiley, D.C. 登録日 1997-06-27 公開日 1997-11-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Atomic structure of the ectodomain from HIV-1 gp41. Nature, 387, 1997
1F23	CONTRIBUTION OF A BURIED HYDROGEN BOND TO HIV-1 ENVELOPE GLYCOPROTEIN STRUCTURE AND FUNCTION 分子名称: TRANSMEMBRANE GLYCOPROTEIN 著者 Liu, J, Shu, W, Fagan, M, Nunberg, J.H, Lu, M. 登録日 2000-05-23 公開日 2001-06-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and functional analysis of the HIV gp41 core containing an Ile573 to Thr substitution: implications for membrane fusion. Biochemistry, 40, 2001
2EZP	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 1-10 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES 分子名称: GP41 著者 Caffrey, M, Gronenborn, A.M, Clore, G.M. 登録日 1998-05-20 公開日 1998-10-14 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41. EMBO J., 17, 1998
6NC2	AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody ACS202 fragment antigen binding 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC011 v4.2 SOSIP gp120, ... 著者 Cottrell, C.A, Ozorowski, G, Yuan, M, Copps, J, Wilson, I.A, Ward, A.B. 登録日 2018-12-10 公開日 2019-06-19 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (5.2 Å) 主引用文献 Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25, 2019
5HFL	Gp41-targeting HIV-1 fusion inhibitors with helical Ile-Asp-Leu tail 分子名称: Envelope glycoprotein,gp41 CHR region 著者 Zhu, Y, Ye, S, Zhang, R. 登録日 2016-01-07 公開日 2017-01-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.294 Å) 主引用文献 Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations Sci Rep, 6, 2016
5HFM	Gp41-targeting HIV-1 fusion inhibitors with hook-like Ile-Asp-Leu tail 分子名称: Envelope glycoprotein gp160,gp41 CHR region, TRIS(HYDROXYETHYL)AMINOMETHANE 著者 Zhu, Y, Ye, S, Zhang, R. 登録日 2016-01-07 公開日 2017-01-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.298 Å) 主引用文献 Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations Sci Rep, 6, 2016
8E1P	Crystal structure of BG505 SOSIP.v4.1-GT1.2 trimer in complex with gl-PGV20 and PGT124 Fabs 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIP.v4.1-GT1.2gp120, ... 著者 Sarkar, A, Kumar, S, Wilson, I.A. 登録日 2022-08-11 公開日 2023-06-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.82 Å) 主引用文献 Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions. Cell Rep Med, 4, 2023
7T9B	ApexGT5 in complex with GT5-d42.16 and RM20A3 Fabs 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Berndsen, Z.T, Ward, A.B. 登録日 2021-12-18 公開日 2022-09-28 最終更新日 2023-07-05 実験手法 ELECTRON MICROSCOPY (3.72 Å) 主引用文献 Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens Immunity, 2022
7T9A	ApexGT2 in complex with GT2-d42.16 and RM20A3 Fabs 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GT2-d42.16 Fab Heavy Chain, ... 著者 Berndsen, Z.T, Ward, A.B. 登録日 2021-12-18 公開日 2022-09-28 最終更新日 2023-07-05 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens Immunity, 2022
6NC3	AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody VRC34 fragment antigen binding 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env AMC011 v4.2 SOSIP gp120, ... 著者 Cottrell, C.A, Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2018-12-10 公開日 2019-06-19 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25, 2019
8T4K	MD64 N332-GT5 SOSIP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MD64 N332-GT5 SOSIP gp120, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2023-06-09 公開日 2024-05-08 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates. Science, 384, 2024
8SW4	BG505 GT1.1 SOSIP in complex with NHP Fabs 21N13, 21M20 and RM20A3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 21M20 heavy chain variable region, ... 著者 Ozorowski, G, Torres, J.L, Zhang, S, Ward, A.B. 登録日 2023-05-17 公開日 2024-05-29 最終更新日 2024-09-11 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site. Sci Immunol, 9, 2024
6UJV	Model of the HIV-1 gp41 membrane-proximal external region, transmembrane domain and cytoplasmic tail (LLP2) 分子名称: Envelope glycoprotein GP41 著者 Piai, A, Fu, Q, Cai, Y, Ghantous, F, Xiao, T, Shaik, M.M, Peng, H, Rits-Volloch, S, Liu, Z, Chen, W, Seaman, M.S, Chen, B, Chou, J.J. 登録日 2019-10-03 公開日 2020-05-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein. Nat Commun, 11, 2020
7LXN	Cryo-EM structure of EDC-crosslinked ConM SOSIP.v7 (ConM-EDC) in complex with bNAb PGT122 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env glycoprotein gp120, ... 著者 Martin, G.M, Ward, A.B, Sattentau, Q.J. 登録日 2021-03-04 公開日 2022-03-09 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.85 Å) 主引用文献 Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens. Npj Vaccines, 8, 2023
7LOI	Model of the HIV-1 gp41 membrane-proximal external region, transmembrane domain and cytoplasmic tail 分子名称: Transmembrane protein gp41 著者 Piai, A, Fu, Q, Sharp, A.K, Bighi, B, Brown, A.M, Chou, J.J. 登録日 2021-02-10 公開日 2021-04-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR Model of the Entire Membrane-Interacting Region of the HIV-1 Fusion Protein and Its Perturbation of Membrane Morphology. J.Am.Chem.Soc., 143, 2021
5WDU	HIV-1 Env BG505 SOSIP.664 H72C-H564C trimer in complex with bNAbs PGT122 Fab, 35O22 Fab and NIH45-46 scFv 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... 著者 Julien, J.-P, Torrents de la Pena, A, Sanders, R.W, Wilson, I.A. 登録日 2017-07-06 公開日 2018-04-04 最終更新日 2022-11-30 実験手法 X-RAY DIFFRACTION (7 Å) 主引用文献 Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization. Cell Rep, 20, 2017
7PC2	HIV-1 Env (BG505 SOSIP.664) in complex with the IgA bNAb 7-269 and the antibody 3BNC117. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC IgG Fab heavy chain, ... 著者 Fernandez, I, Bontems, F, Pehau-Arnaudet, G, Rey, F. 登録日 2021-08-03 公開日 2022-02-23 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller. J.Exp.Med., 219, 2022
4TVP	Crystal Structure of the HIV-1 BG505 SOSIP.664 Env Trimer Ectodomain, Comprising Atomic-Level Definition of Pre-Fusion gp120 and gp41, in Complex with Human Antibodies PGT122 and 35O22 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy chain, ... 著者 Pancera, M, Zhou, T, Kwong, P.D. 登録日 2014-06-27 公開日 2014-10-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure and immune recognition of trimeric pre-fusion HIV-1 Env. Nature, 514, 2014
9BF6	Cryo-EM structure of the HIV-1 WITO IDL Env trimer in complex with PGT122 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, Envelope glycoprotein gp41, ... 著者 Gorman, J, Kwong, P.D. 登録日 2024-04-16 公開日 2024-07-31 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation. Cell Rep, 43, 2024
9BER	Cryo-EM structure of the HIV-1 JR-FL IDL Env trimer in complex with PGT122 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... 著者 Gorman, J, Kwong, P.D. 登録日 2024-04-16 公開日 2024-07-31 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation. Cell Rep, 43, 2024
7T0O	cryoEM reconstruction of the HIV gp140 in complex with the extracellular domains of CD4 and the adnectin domain of Combinectin. The gp140 and CD4 coordinates from entry 6EDU were rigid body fitted to the EM map along withe the crystal structure of CD4+adnectin 分子名称: Adnectin, BG505 SOSIP.664 gp140, T-cell surface glycoprotein CD4 著者 Concha, N.O, William, S.P, Wenzel, D.L. 登録日 2021-11-30 公開日 2022-01-12 実験手法 ELECTRON MICROSCOPY (8.7 Å) 主引用文献 Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment. J.Mol.Biol., 434, 2021
7SQ1	BG505.MD39TS Env trimer in complex with Fab from antibody C05 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C05 Fab Light chain, ... 著者 Moore, A, Du, J, Xu, Z, Walker, S, Kulp, D.W, Pallesen, J. 登録日 2021-11-04 公開日 2022-06-22 最終更新日 2022-12-07 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer. Nat Commun, 13, 2022

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