PDB: 608 件ウェブページステータス検索Chemie searchBIRD

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4O46	14-3-3-gamma in complex with influenza NS1 C-terminal tail phosphorylated at S228 分子名称: 14-3-3 protein gamma, Nonstructural protein 1, UNKNOWN ATOM OR ION, ... 著者 Qin, S, Liu, Y, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2013-12-18 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nat Commun, 5, 2014
5HF3	Crystal structure of C-terminal modified Tau peptide-hybrid 201D with 14-3-3sigma 分子名称: 14-3-3 protein sigma, modified Tau peptide 著者 Bartel, M, Milroy, L.G, Brunsveld, L, Ottmann, C. 登録日 2016-01-06 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Stabilizer-Guided Inhibition of Protein-Protein Interactions. Angew.Chem.Int.Ed.Engl., 54, 2015
2V7D	14-3-3 protein zeta in complex with Thr758 phosphorylated integrin beta2 peptide 分子名称: 14-3-3 PROTEIN ZETA/DELTA, INTEGRIN BETA CHAIN, BETA 2 VARIANT 著者 Takala, H, Ylanne, J. 登録日 2007-07-30 公開日 2008-06-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Beta2 Integrin Phosphorylation on Thr758 Acts as a Molecular Switch to Regulate 14-3-3 and Filamin Binding. Blood, 112, 2008
4QLI	A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation 分子名称: 14-3-3 protein sigma, GLYCEROL, MAGNESIUM ION, ... 著者 Bier, D, Ottmann, C. 登録日 2014-06-12 公開日 2015-06-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation To be Published
4N7G	Crystal structure of 14-3-3zeta in complex with a peptide derived from ExoS 分子名称: 14-3-3 protein zeta/delta, Exoenzyme S, HEXAETHYLENE GLYCOL 著者 Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C. 登録日 2013-10-15 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. Angew.Chem.Int.Ed.Engl., 53, 2014
4N84	Crystal structure of 14-3-3zeta in complex with a 12-carbon-linker cyclic peptide derived from ExoS 分子名称: 14-3-3 protein zeta/delta, Exoenzyme S 著者 Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C. 登録日 2013-10-17 公開日 2014-02-19 最終更新日 2014-03-12 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. Angew.Chem.Int.Ed.Engl., 53, 2014
1A38	14-3-3 PROTEIN ZETA BOUND TO R18 PEPTIDE 分子名称: 14-3-3 PROTEIN ZETA, R18 PEPTIDE (PHCVPRDLSWLDLEANMCLP) 著者 Petosa, C, Masters, S.C, Pohl, J, Wang, B, Fu, H, Liddington, R.C. 登録日 1998-01-28 公開日 1999-03-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove. J.Biol.Chem., 273, 1998
4F7R	Crystal structure of 14-3-3 protein from Giardia intestinalis 分子名称: 14-3-3 protein, SULFATE ION 著者 Fiorillo, A, Ilari, A, Lalle, M. 登録日 2012-05-16 公開日 2013-05-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The Crystal Structure of Giardia duodenalis 14-3-3 in the Apo Form: When Protein Post-Translational Modifications Make the Difference. Plos One, 9, 2014
3E6Y	Structure of 14-3-3 in complex with the differentiation-inducing agent Cotylenin A 分子名称: 14-3-3-like protein C, CHLORIDE ION, Cotylenin A, ... 著者 Ottmann, C, Weyand, M, Wittinghofer, A, Oecking, C. 登録日 2008-08-17 公開日 2009-03-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A J.Mol.Biol., 386, 2009
3EFZ	Crystal Structure of a 14-3-3 protein from cryptosporidium parvum (cgd1_2980) 分子名称: 1,2-ETHANEDIOL, 14-3-3 protein 著者 Wernimont, A.K, Dong, A, Qiu, W, Lew, J, Wasney, G.A, Vedadi, M, Kozieradzki, I, Zhao, Y, Ren, H, Alam, Z, Lin, Y.H, Sundstrom, M, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC) 登録日 2008-09-10 公開日 2008-09-23 最終更新日 2012-02-22 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Characterization of 14-3-3 proteins from Cryptosporidium parvum. Plos One, 6, 2011
4JC3	14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface 分子名称: 14-3-3 protein sigma, Estrogen receptor Peptide, MAGNESIUM ION 著者 Bier, D, Ottmann, C. 登録日 2013-02-21 公開日 2013-05-15 最終更新日 2017-06-07 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
4FR3	Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilizer 16-O-Me-FC-H 分子名称: (4R,5R,6R,6aS,9S,9aE,10aR)-5-hydroxy-9-(methoxymethyl)-6,10a-dimethyl-3-(propan-2-yl)-1,2,4,5,6,6a,7,8,9,10a-decahydrodicyclopenta[a,d][8]annulen-4-yl alpha-D-glucopyranoside, 14-3-3 protein sigma, MAGNESIUM ION, ... 著者 Ottmann, C, Anders, C, Schumacher, B. 登録日 2012-06-26 公開日 2013-05-08 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of k(+) channels at the cell surface. Chem.Biol., 20, 2013
4N7Y	Crystal structure of 14-3-3zeta in complex with a 8-carbon-linker cyclic peptide derived from ExoS 分子名称: 14-3-3 protein zeta/delta, Exoenzyme S 著者 Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C. 登録日 2013-10-16 公開日 2014-02-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. Angew.Chem.Int.Ed.Engl., 53, 2014
4FJ3	14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide 分子名称: 14-3-3 protein zeta/delta, RAF proto-oncogene serine/threonine-protein kinase 著者 Ottmann, C, Molzan, M. 登録日 2012-06-11 公開日 2012-09-05 最終更新日 2013-07-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Synergistic binding of the phosphorylated S233- and S259-binding sites of C-RAF to one 14-3-3zeta dimer J.Mol.Biol., 423, 2012
5ULO	Crystal Structure of 14-3-3 zeta in Complex with a Serine 124-phosphorylated TBC1D7 peptide 分子名称: 1,2-ETHANEDIOL, 14-3-3 protein zeta/delta, L-PROLINAMIDE, ... 著者 DONG, A, HU, J, MADIGAN, J, WALKER, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, TONG, Y, Structural Genomics Consortium (SGC) 登録日 2017-01-25 公開日 2018-01-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Crystal Structure of 14-3-3 zeta in Complex with a Serine 124-phosphorylated TBC1D7 peptide to be published
3IQU	Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (6mer) 分子名称: 14-3-3 protein sigma, 6-mer from RAF proto-oncogene serine/threonine-protein kinase, CHLORIDE ION, ... 著者 Ottmann, C, Weyand, M. 登録日 2009-08-21 公開日 2010-09-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling. Mol.Cell.Biol., 30, 2010
3IQJ	Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (10mer) 分子名称: 10-mer peptide from RAF proto-oncogene serine/threonine-protein kinase, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Ottmann, C, Weyand, M. 登録日 2009-08-20 公開日 2010-09-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling. Mol.Cell.Biol., 30, 2010
4JDD	14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface 分子名称: 14-3-3 protein sigma, Estrogen receptor Peptide, FUSICOCCIN 著者 Bier, D, Ottmann, C. 登録日 2013-02-25 公開日 2013-05-15 最終更新日 2017-06-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
3CU8	Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome 分子名称: 14-3-3 protein zeta/delta, MAGNESIUM ION, PROPANOIC ACID, ... 著者 Schumacher, B, Weyand, M, Kuhlmann, J, Ottmann, C. 登録日 2008-04-16 公開日 2009-05-05 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling. Mol. Cell. Biol., 30, 2010
3IQV	Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (6mer) and stabilisator Fusicoccin 分子名称: 14-3-3 protein sigma, 6-mer peptide from RAF proto-oncogene serine/threonine-protein kinase, CHLORIDE ION, ... 著者 Ottmann, C, Weyand, M. 登録日 2009-08-21 公開日 2010-09-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling. Mol.Cell.Biol., 30, 2010
5WFX	Structural basis for the interaction of 14-3-3beta with Tricarboxylic Acid Cycle intermediate Malate 分子名称: 14-3-3 protein beta/alpha 著者 Hou, Z.Q. 登録日 2017-07-12 公開日 2018-05-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.651 Å) 主引用文献 Structural basis for the interaction of 14-3-3 beta withTricarboxylic Acid Cycle intermediate Malate To Be Published
5WFU	Structural basis for the interaction of 14-3-3beta with Tricarboxylic Acid Cycle intermediate Malate 分子名称: 14-3-3 protein beta/alpha, D-MALATE 著者 Hou, Z.Q, Liu, X.Y. 登録日 2017-07-12 公開日 2018-07-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural basis for the interaction of 14-3-3beta with Tricarboxylic Acid Cycle intermediate Malate To Be Published
1A4O	14-3-3 PROTEIN ZETA ISOFORM 分子名称: 14-3-3 PROTEIN ZETA 著者 Liu, D, Bienkowska, J, Petosa, C, Collier, R.J, Fu, H, Liddington, R.C. 登録日 1998-02-01 公開日 1999-03-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the zeta isoform of the 14-3-3 protein. Nature, 376, 1995
1A37	14-3-3 PROTEIN ZETA BOUND TO PS-RAF259 PEPTIDE 分子名称: 14-3-3 PROTEIN ZETA, PS-RAF259 PEPTIDE LSQRQRST(SEP)TPNVHM 著者 Petosa, C, Masters, S.C, Pohl, J, Wang, B, Fu, H, Liddington, R.C. 登録日 1998-01-28 公開日 1999-03-02 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove. J.Biol.Chem., 273, 1998
8QT5	Crystal structure of Arabidopsis thaliana 14-3-3 isoform lambda in complex with a phosphopeptide from the transcription factor BZR1. 分子名称: 14-3-3-like protein G-BOX factor 14 lambda,Protein BRASSINAZOLE-RESISTANT 1, ACETATE ION 著者 Hothorn, M, Obergfell, E. 登録日 2023-10-12 公開日 2023-10-25 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Mechanistic insights into the function of 14-3-3 proteins as negative regulators of brassinosteroid signaling in Arabidopsis. Plant Cell.Physiol., 2024

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