Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4Y13
DownloadVisualize
BU of 4y13 by Molmil
SdiA in complex with octanoyl-rac-glycerol
分子名称: (2S)-2,3-dihydroxypropyl octanoate, GLYCEROL, SULFATE ION, ...
著者Nguyen, N.X, Nguyen, Y, Sperandio, V, Jiang, Y.
登録日2015-02-06
公開日2015-04-08
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (3.096 Å)
主引用文献Structural and Mechanistic Roles of Novel Chemical Ligands on the SdiA Quorum-Sensing Transcription Regulator.
Mbio, 6, 2015
6V7X
DownloadVisualize
BU of 6v7x by Molmil
Structure of a phage-encoded quorum sensing anti-activator, Aqs1 bound to LasR
分子名称: N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE, QUORUM SENSING ANTI-ACTIVATOR PROTEIN AQS1, Transcriptional regulator LasR
著者Shah, M, Moraes, T.F, Maxwell, K.L.
登録日2019-12-09
公開日2020-12-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa.
Mol.Cell, 81, 2021
6V7W
DownloadVisualize
BU of 6v7w by Molmil
Crystal structure of LasR-Aqs1 complex from Pseudomonas aeruginosa
分子名称: N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE, QUORUM SENSING ANTI-ACTIVATOR PROTEIN AQS1, Transcriptional regulator LasR
著者Shah, M, Moraes, T.F, Maxwell, K.L.
登録日2019-12-09
公開日2020-12-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa.
Mol.Cell, 81, 2021
8DQ1
DownloadVisualize
BU of 8dq1 by Molmil
Quorum-sensing receptor RhlR bound to PqsE
分子名称: 2-aminobenzoylacetyl-CoA thioesterase, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, DNA (5'-D(*AP*CP*CP*TP*GP*CP*CP*AP*GP*AP*CP*TP*GP*CP*AP*CP*AP*G)-3'), ...
著者Paczkowski, J.E, Fromme, J.C, Feathers, J.R.
登録日2022-07-18
公開日2022-12-07
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulation.
Structure, 30, 2022
8DQ0
DownloadVisualize
BU of 8dq0 by Molmil
Quorum-sensing receptor RhlR bound to PqsE
分子名称: 2-aminobenzoylacetyl-CoA thioesterase, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, RhlR protein
著者Paczkowski, J.E, Fromme, J.C, Feathers, J.R.
登録日2022-07-18
公開日2022-12-07
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulation.
Structure, 30, 2022
6CBQ
DownloadVisualize
BU of 6cbq by Molmil
Crystal structure of QscR bound to agonist S3
分子名称: (2S)-2-hexyl-N-[(3S)-2-oxooxolan-3-yl]decanamide, LuxR family transcriptional regulator
著者Churchill, M.E.A, Wysoczynski-Horita, C.L.
登録日2018-02-05
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands.
Mol. Microbiol., 108, 2018
1H0M
DownloadVisualize
BU of 1h0m by Molmil
Three-dimensional structure of the quorum sensing protein TraR bound to its autoinducer and to its target DNA
分子名称: 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, 5'-D(*AP*TP*GP*TP*GP*CP*AP*GP*AP*TP *CP*TP*GP*CP*AP*CP*AP*T)-3', Transcriptional activator protein TraR
著者Vannini, A, Volpari, C, Gargioli, C, Muraglia, E, Cortese, R, De Francesco, R, Neddermann, P, Di Marco, S.
登録日2002-06-25
公開日2002-08-29
最終更新日2020-12-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Crystal Structure of the Quorum Sensing Protein Trar Bound to its Autoinducer and Target DNA
Embo J., 21, 2002
6CC0
DownloadVisualize
BU of 6cc0 by Molmil
Crystal structure of QscR bound to C12-homoserine lactone
分子名称: LuxR family transcriptional regulator, N-[(3S)-2-oxooxolan-3-yl]dodecanamide
著者Churchill, M.E.A, Wysoczynski-Horita, C.L.
登録日2018-02-05
公開日2018-02-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands.
Mol. Microbiol., 108, 2018
1L3L
DownloadVisualize
BU of 1l3l by Molmil
Crystal structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA
分子名称: 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, 5'-D(*GP*AP*TP*GP*TP*GP*CP*AP*GP*AP*TP*CP*TP*GP*CP*AP*CP*AP*TP*C)-3', Transcriptional activator protein traR
著者Zhang, R, Pappas, T, Brace, J.L, Miller, P.C, Oulmassov, T, Molyneaux, J.M, Anderson, J.C, Bashkin, J.K, Winans, S.C, Joachimiak, A.
登録日2002-02-27
公開日2002-07-03
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA.
Nature, 417, 2002
6KJU
DownloadVisualize
BU of 6kju by Molmil
Huge conformation shift of Vibrio cholerae VqmA dimer in the absence of target DNA provides insight into DNA-binding mechanisms of LuxR-type receptors
分子名称: 3,5-dimethylpyrazin-2-ol, Helix-turn-helix transcriptional regulator
著者Wu, H, Li, M.J, Guo, H.J, Zhou, H, Wang, W.W, Xu, Q, Xu, C.Y, Yu, F, He, J.H.
登録日2019-07-23
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Large conformation shifts of Vibrio cholerae VqmA dimer in the absence of target DNA provide insight into DNA-binding mechanisms of LuxR-type receptors.
Biochem.Biophys.Res.Commun., 520, 2019
8A5R
DownloadVisualize
BU of 8a5r by Molmil
Crystal structure of light-activated DNA-binding protein EL222 from Erythrobacter litoralis crystallized and measured in dark.
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Koval, T, Chaudhari, A, Fuertes, G, Andersson, I, Dohnalek, J.
登録日2022-06-15
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献EL222 from Erythrobacter litoralis.
To Be Published
8A5S
DownloadVisualize
BU of 8a5s by Molmil
Crystal structure of light-activated DNA-binding protein EL222 from Erythrobacter litoralis crystallized in dark, measured illuminated.
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Koval, T, Chaudhari, A, Fuertes, G, Andersson, I, Dohnalek, J.
登録日2022-06-15
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献EL222 from Erythrobacter litoralis.
To Be Published
4LFU
DownloadVisualize
BU of 4lfu by Molmil
Crystal structure of Escherichia coli SdiA in the space group C2
分子名称: CHLORIDE ION, Regulatory protein SdiA, TETRAETHYLENE GLYCOL
著者Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K.
登録日2013-06-27
公開日2014-03-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
4LGW
DownloadVisualize
BU of 4lgw by Molmil
Crystal structure of Escherichia coli SdiA in the space group P6522
分子名称: GLYCEROL, Regulatory protein SdiA
著者Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K.
登録日2013-06-28
公開日2014-03-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
8B4A
DownloadVisualize
BU of 8b4a by Molmil
Nativ complex of PqsE and RhlR with autoinducer C4-HSL
分子名称: 2-aminobenzoylacetyl-CoA thioesterase, FE (III) ION, N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide, ...
著者Borgert, S.R, Blankenfeldt, W.
登録日2022-09-20
公開日2022-12-14
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.
Nat Commun, 13, 2022
3SZT
DownloadVisualize
BU of 3szt by Molmil
Quorum Sensing Control Repressor, QscR, Bound to N-3-oxo-dodecanoyl-L-Homoserine Lactone
分子名称: N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE, Quorum-sensing control repressor, SODIUM ION
著者Churchill, M.E.A, Lintz, M.J.
登録日2011-07-19
公開日2011-09-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of QscR, a Pseudomonas aeruginosa quorum sensing signal receptor.
Proc.Natl.Acad.Sci.USA, 108, 2011
3QP6
DownloadVisualize
BU of 3qp6 by Molmil
Crystal structure of CviR (Chromobacterium violaceum 12472) bound to C6-HSL
分子名称: CviR transcriptional regulator, N-[(3S)-2-oxotetrahydrofuran-3-yl]hexanamide
著者Chen, G, Swem, L, Swem, D, Stauff, D, O'Loughlin, C, Jeffrey, P, Bassler, B, Hughson, F.
登録日2011-02-11
公開日2011-03-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A strategy for antagonizing quorum sensing.
Mol.Cell, 42, 2011
3QP5
DownloadVisualize
BU of 3qp5 by Molmil
Crystal structure of CviR bound to antagonist chlorolactone (CL)
分子名称: 4-(4-chlorophenoxy)-N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide, CviR transcriptional regulator
著者Chen, G, Swem, L, Swem, D, Stauff, D, O'Loughlin, C, Jeffrey, P, Bassler, B, Hughson, F.
登録日2011-02-11
公開日2011-03-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.249 Å)
主引用文献A strategy for antagonizing quorum sensing.
Mol.Cell, 42, 2011
4Y17
DownloadVisualize
BU of 4y17 by Molmil
SdiA in complex with 3-oxo-C8-homoserine lactone
分子名称: 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, Transcriptional regulator of ftsQAZ gene cluster
著者Nguyen, N.X, Nguyen, Y, Sperandio, V, Jiang, Y.
登録日2015-02-06
公開日2015-04-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Structural and Mechanistic Roles of Novel Chemical Ligands on the SdiA Quorum-Sensing Transcription Regulator.
Mbio, 6, 2015
6MWW
DownloadVisualize
BU of 6mww by Molmil
LasR LBD:BB0126 complex
分子名称: 4-[3-(methylsulfonyl)phenoxy]-N-[(1R,3R,5R)-2-oxobicyclo[3.1.0]hexan-3-yl]butanamide, Transcriptional regulator LasR
著者Bassler, B.L, Paczkowski, J.E.
登録日2018-10-30
公開日2019-04-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
6MVN
DownloadVisualize
BU of 6mvn by Molmil
LasR LBD L130F:3OC10HSL complex
分子名称: 3-oxo-N-[(3S)-2-oxotetrahydrofuran-3-yl]decanamide, Transcriptional regulator LasR
著者Bassler, B.L, Paczkowski, J.E.
登録日2018-10-26
公開日2019-01-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural determinants driving homoserine lactone ligand selection in thePseudomonas aeruginosaLasR quorum-sensing receptor.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6MWL
DownloadVisualize
BU of 6mwl by Molmil
LasR LBD:mBTL complex
分子名称: 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, Transcriptional regulator LasR
著者Bassler, B.L, Paczkowski, J.E.
登録日2018-10-29
公開日2019-04-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
6MWZ
DownloadVisualize
BU of 6mwz by Molmil
LasR LBD T75V/Y93F/A127W:BB0126
分子名称: 4-[3-(methylsulfonyl)phenoxy]-N-[(1S,3S,5S)-2-oxobicyclo[3.1.0]hexan-3-yl]butanamide, ALA-HIS-HIS-HIS-HIS-ALA, Transcriptional regulator LasR
著者Bassler, B.L, Paczkowski, J.E.
登録日2018-10-30
公開日2019-04-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.657 Å)
主引用文献An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
6MWH
DownloadVisualize
BU of 6mwh by Molmil
LasR LBD:BB0020 complex
分子名称: 2-(3-bromophenoxy)-N-[(1S,2S,3R,5S)-2-hydroxybicyclo[3.1.0]hexan-3-yl]acetamide, Transcriptional regulator LasR
著者Bassler, B.L, Paczkowski, J.E.
登録日2018-10-29
公開日2019-04-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
7PK5
DownloadVisualize
BU of 7pk5 by Molmil
Phosphodiesterase PdeL (EAL domain of crystals comprising full-length protein)
分子名称: Cyclic di-GMP phosphodiesterase PdeL
著者Fadel, J, Schirmer, T.
登録日2021-08-25
公開日2022-09-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Phosphodiesterase PdeL (EAL domain of crystals comprising full-length protein)
To Be Published

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon