PDB: 275 件ウェブページステータス検索Chemie searchBIRD

---

7N2M	Crystal structure of DNA polymerase alpha catalytic core in complex with dCTP and template/primer having T-C mismatch at the post-insertion site 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*T*AP*GP*TP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), DNA polymerase alpha catalytic subunit, ... 著者 Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. 登録日 2021-05-29 公開日 2022-04-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural and functional insight into mismatch extension by human DNA polymerase alpha. Proc.Natl.Acad.Sci.USA, 119, 2022
8Q3R	Cryo-EM structure of the DNA polymerase holoenzyme E9-A20-D4 of vaccinia virus 分子名称: DNA polymerase, DNA polymerase processivity factor component OPG148, Uracil-DNA glycosylase 著者 Burmeister, W.P, Ballandras-Colas, A, Boettcher, B, Grimm, C. 登録日 2023-08-04 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus. Plos Pathog., 20, 2024
1IG9	Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase 分子名称: 5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*(DOC))-3', CALCIUM ION, ... 著者 Franklin, M.C, Wang, J, Steitz, T.A. 登録日 2001-04-17 公開日 2001-06-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase Cell(Cambridge,Mass.), 105, 2001
5VU5	TNA polymerase, apo 分子名称: DNA polymerase 著者 Chim, N, Chaput, J.C. 登録日 2017-05-18 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
7LUF	HSV1 polymerase ternary complex with dsDNA and PNU-183792 分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ... 著者 Hayes, R.P, Klein, D. 登録日 2021-02-22 公開日 2021-04-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase. Nat Commun, 12, 2021
5VU7	TNA polymerase, open ternary complex 分子名称: 5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXYTETRAHYDROFURAN-3-YL DIHYDROGEN PHOSPHATE, DNA polymerase, DNA template, ... 著者 Chim, N, Chaput, J.C. 登録日 2017-05-18 公開日 2017-12-06 最終更新日 2017-12-13 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
1CLQ	CRYSTAL STRUCTURE OF A REPLICATION FORK DNA POLYMERASE EDITING COMPLEX AT 2.7 A RESOLUTION 分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*TP*AP*GP*TP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*AP*CP*TP*AP*CP*T)-3'), ... 著者 Shamoo, Y, Steitz, T.A. 登録日 1999-04-30 公開日 1999-10-28 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex. Cell(Cambridge,Mass.), 99, 1999
5VU9	TNA polymerase, translocated product 分子名称: DNA polymerase, DNA template, DNA/TNA hybrid primer 著者 Chim, N, Chaput, J.C. 登録日 2017-05-18 公開日 2017-12-06 最終更新日 2017-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
5OMV	Ternary complex of 9N DNA polymerase in the replicative state with two metal ions in the active site 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, DNA primer, ... 著者 Betz, K, Marx, A, Diederichs, K. 登録日 2017-08-01 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
6TNY	Processive human polymerase delta holoenzyme 分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... 著者 Lancey, C, Hamdan, S.M, De Biasio, A. 登録日 2019-12-10 公開日 2019-12-18 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
5VU8	TNA polymerase, closed ternary complex 分子名称: DNA polymerase, DNA template, DNA/TNA hybrid primer, ... 著者 Chim, N, Chaput, J.C. 登録日 2017-05-18 公開日 2017-12-06 最終更新日 2017-12-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
2DTU	Crystal structure of the beta hairpin loop deletion variant of RB69 gp43 in complex with DNA containing an abasic site analog 分子名称: 5'-D(*CP*GP*(3DR)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*GP*A)-3', DNA polymerase 著者 Aller, P, Hogg, M, Konigsberg, W, Wallace, S.S, Doublie, S. 登録日 2006-07-15 公開日 2006-12-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. J.Biol.Chem., 282, 2007
5VU6	TNA polymerase binary complex with primer/template duplex 分子名称: DNA polymerase, DNA template, DNA/TNA hybrid primer 著者 Chim, N, Chaput, J.C. 登録日 2017-05-18 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
5OMF	Closed, ternary structure of KOD DNA polymerase 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*C)-3'), ... 著者 Kropp, H.M, Betz, K, Wirth, J, Diederichs, K, Marx, A. 登録日 2017-07-31 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.092 Å) 主引用文献 Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
5OMQ	Ternary complex of 9N DNA polymerase in the replicative state with three metal ions in the active site 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA Primer, DNA Template, ... 著者 Betz, K, Marx, A, Diederichs, K. 登録日 2017-08-01 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
2DY4	Crystal structure of RB69 GP43 in complex with DNA containing Thymine Glycol 分子名称: 5'-D(*CP*GP*(CTG)P*GP*GP*AP*AP*TP*GP*A*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*T*CP*AP*TP*TP*CP*CP*A)-3', DNA polymerase 著者 Aller, P, Rould, M.A, Hogg, M, Wallace, S.S, Doublie, S. 登録日 2006-09-06 公開日 2007-01-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. Proc.Natl.Acad.Sci.USA, 104, 2007
4AIL	Crystal Structure of an Evolved Replicating DNA Polymerase 分子名称: 5'-D(*AP*CP*GP*GP*GP*TP*AP*AP*GP*CP*AP)-3', 5'-D(*TP*GP*CP*TP*TP*AP*CP*DOCP)-3', DNA POLYMERASE 著者 Wynne, S.A, Holliger, P, Leslie, A.G.W. 登録日 2012-02-10 公開日 2012-03-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structures of an Apo and a Binary Complex of an Evolved Archeal B Family DNA Polymerase Capable of Synthesising Highly Cy-Dye Labelled DNA. Plos One, 8, 2013
6V93	Structure of DNA Polymerase Zeta/DNA/dNTP Ternary Complex 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA, ... 著者 Malik, R, Kopylov, M, Jain, R, Ubarrextena-Belandia, I, Aggarwal, A.K. 登録日 2019-12-13 公開日 2020-08-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure and mechanism of B-family DNA polymerase zeta specialized for translesion DNA synthesis. Nat.Struct.Mol.Biol., 27, 2020
6V8P	Structure of DNA Polymerase Zeta (Apo) 分子名称: DNA polymerase delta small subunit, DNA polymerase delta subunit 3, DNA polymerase zeta catalytic subunit, ... 著者 Malik, R, Gomez-Llorente, Y, Ubarretxena-Belandia, I, Aggarwal, A.K. 登録日 2019-12-11 公開日 2020-08-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structure and mechanism of B-family DNA polymerase zeta specialized for translesion DNA synthesis. Nat.Struct.Mol.Biol., 27, 2020
4B08	Yeast DNA polymerase alpha, Selenomethionine protein 分子名称: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A 著者 Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L. 登録日 2012-06-29 公開日 2013-02-27 最終更新日 2013-05-01 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Mechanism for Priming DNA Synthesis by Yeast DNA Polymerase Alpha Elife, 2, 2013
4AHC	Crystal Structure of an Evolved Replicating DNA Polymerase 分子名称: DNA POLYMERASE, GLYCEROL 著者 Wynne, S.A, Holliger, P, Leslie, A.G.W. 登録日 2012-02-06 公開日 2012-03-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of an Apo and a Binary Complex of an Evolved Archeal B Family DNA Polymerase Capable of Synthesising Highly Cy-Dye Labelled DNA. Plos One, 8, 2013
2GV9	Crystal structure of the Herpes Simplex virus type 1 DNA polymerase 分子名称: DNA polymerase, GUANIDINE, MERCURY (II) ION, ... 著者 Liu, S. 登録日 2006-05-02 公開日 2006-05-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Crystal structure of the herpes simplex virus 1 DNA polymerase. J.Biol.Chem., 281, 2006
4M41	RB69 DNA polymerase ternary complex with dG/dT at position n-3 of primer/tempLate duplex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Konigsberg, W.H. 登録日 2013-08-06 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant. Protein Sci., 23, 2014
4M3Z	RB69 DNA polymerase ternary complex with dG/dT at position n-2 of primer/tempLate duplex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Konigsberg, W.H. 登録日 2013-08-06 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant. Protein Sci., 23, 2014
8D0K	Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template - PRIM2C advanced PIC 分子名称: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... 著者 He, Q, Lin, X, Chavez, B.L, Agrawal, S, Lusk, B.L, Lim, C. 登録日 2022-05-26 公開日 2022-06-22 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (4.27 Å) 主引用文献 Structures of the human CST-Pol alpha-primase complex bound to telomere templates. Nature, 608, 2022

<1234567891011>