8D0K

Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template - PRIM2C advanced PIC

Summary for 8D0K

• Entry DOI: 10.2210/pdb8d0k/pdb
• EMDB information: 27107
• Descriptor: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... (8 entities in total)
• Functional Keywords: telomere, c-strand, complex, 4xtel-foldback dna template, prim2c, replication-dna complex, replication/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 568799.03

Authors

He, Q.,Lin, X.,Chavez, B.L.,Agrawal, S.,Lusk, B.L.,Lim, C. (deposition date: 2022-05-26, release date: 2022-06-22, Last modification date: 2024-02-14)

• Primary citation: He, Q.,Lin, X.,Chavez, B.L.,Agrawal, S.,Lusk, B.L.,Lim, C.J.; Structures of the human CST-Pol alpha-primase complex bound to telomere templates.; Nature, 608:826-832, 2022; PubMed: 35830881; DOI: 10.1038/s41586-022-05040-1

Experimental method

ELECTRON MICROSCOPY (4.27 Å)