PDB: 100 件ウェブページステータス検索Chemie searchBIRD

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6OGX	Ternary complex of OX40R (TNFRSF4) bound to Fab1 and Fab2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 1 Heavy Chain, Fab1 Light Chain, ... 著者 Ultsch, M.H, Boenig, G, Harris, S.F. 登録日 2019-04-03 公開日 2019-07-10 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members. Mabs, 11, 2019
6NG3	Crystal structure of human CD160 and HVEM complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD160 antigen,Tumor necrosis factor receptor superfamily member 14, MAGNESIUM ION, ... 著者 Liu, W, Bonanno, J, Almo, S.C. 登録日 2018-12-21 公開日 2019-07-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Structural Basis of CD160:HVEM Recognition. Structure, 27, 2019
6MKZ	Crystal structure of murine 4-1BB/4-1BBL complex 分子名称: Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Bitra, A, Zajonc, D.M, Doukov, T. 登録日 2018-09-26 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding. J. Biol. Chem., 294, 2019
6MI2	Structure of the human 4-1BB / Utomilumab Fab complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SULFATE ION, ... 著者 Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. 登録日 2018-09-19 公開日 2018-11-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab. Nat Commun, 9, 2018
6MHR	Structure of the human 4-1BB / Urelumab Fab complex 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, MALONATE ION, ... 著者 Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. 登録日 2018-09-18 公開日 2018-11-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab. Nat Commun, 9, 2018
6MGP	Structure of human 4-1BB / 4-1BBL complex 分子名称: ACETATE ION, GLYCEROL, Tumor necrosis factor ligand superfamily member 9, ... 著者 Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. 登録日 2018-09-14 公開日 2018-11-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab Nat Commun, 9, 2018
6A3W	Complex structure of 4-1BB and utomilumab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor receptor superfamily member 9, utomilumab VH, ... 著者 Li, Y, Tan, S, Zhang, C, Chai, Y, Qi, J, Tien, P, Gao, S, Gao, G.F. 登録日 2018-06-17 公開日 2018-10-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab. Cell Rep, 25, 2018
6A3V	Complex structure of human 4-1BB and 4-1BBL 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9 著者 Li, Y, Zhang, C, Chai, Y, Qi, J, Tien, P, Gao, S, Gao, G.F. 登録日 2018-06-17 公開日 2018-10-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.391 Å) 主引用文献 Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab. Cell Rep, 25, 2018
6CU0	Crystal structure of 4-1BBL/4-1BB (C121S) complex in P21 space group 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9 著者 Aruna, B, Zajonc, D.M, Doukov, T. 登録日 2018-03-23 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier. J. Biol. Chem., 293, 2018
6CPR	Crystal structure of 4-1BBL/4-1BB complex in C2 space group 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... 著者 Aruna, B, Zajonc, D.M. 登録日 2018-03-14 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier. J. Biol. Chem., 293, 2018
6FAX	Complex of Human CD40 Ectodomain with Lob 7.4 Fab 分子名称: Lob 7.4 heavy chain, Lob 7.4 light chain, Tumor necrosis factor receptor superfamily member 5 著者 Orr, C.M, Tews, I, Pearson, A.R. 登録日 2017-12-18 公開日 2018-02-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies. Cancer Cell, 33, 2018
6BWV	Crystal Structure of the 4-1BB/4-1BBL Complex 分子名称: DI(HYDROXYETHYL)ETHER, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9 著者 Oganesyan, V, Gilbreth, R.N, Baca, M. 登録日 2017-12-15 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the human 4-1BB/4-1BBL complex. J. Biol. Chem., 293, 2018
5WJF	Crystal structure of murine 4-1BB from HEK293T cells in P21212 space group 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor receptor superfamily member 9 著者 Zajonc, D.M, Doukov, T, Bitra, A. 登録日 2017-07-21 公開日 2017-12-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling. J. Biol. Chem., 293, 2018
5WIW	Crystal structure of murine 4-1BB N128A mutant from HEK293T cells in P43 space group 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SULFATE ION, ... 著者 Zajonc, D.M, Bitra, A. 登録日 2017-07-20 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling. J. Biol. Chem., 293, 2018
5WI8	Crystal structure of murine 4-1BB from HEK293T cells in P21 space group 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Zajonc, D.M, Bitra, A. 登録日 2017-07-18 公開日 2017-12-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling. J. Biol. Chem., 293, 2018
5TLJ	COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND M2191 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, M2177 HEAVY CHAIN, ... 著者 Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. 登録日 2016-10-11 公開日 2017-02-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography. Mol. Immunol., 83, 2017
5TLK	COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND H2191 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, H2191 HEAVY CHAIN, ... 著者 Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. 登録日 2016-10-11 公開日 2017-02-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography. Mol. Immunol., 83, 2017
5TL5	COMPLEX BETWEEN HUMAN CD27 AND ANTIBODY M2177 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, M2177 HEAVY CHAIN, ... 著者 Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. 登録日 2016-10-10 公開日 2017-06-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of CD27 in complex with a neutralizing noncompeting antibody. Acta Crystallogr F Struct Biol Commun, 73, 2017
5T2Q	Unliganded Human HVEM at 1.9A in P 1 21 1 分子名称: Tumor necrosis factor receptor superfamily member 14 著者 Nemcovicova, I, Zajonc, D.M. 登録日 2016-08-24 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Unliganded Human HVEM at 1.9A in P 1 21 1 To Be Published
5T2R	Unliganded Human HVEM at 2.1A in P 21 21 21 分子名称: Tumor necrosis factor receptor superfamily member 14 著者 Nemcovicova, I, Zajonc, D.M. 登録日 2016-08-24 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Unliganded Human HVEM at 2.1A in P 21 21 21 To Be Published
5L36	Crystal Structure of a human FasL mutant in complex with human DcR3 分子名称: SODIUM ION, Tumor necrosis factor ligand superfamily member 6, Tumor necrosis factor receptor superfamily member 6B 著者 Liu, W, Bonanno, J.B, Almo, S.C. 登録日 2016-08-03 公開日 2016-09-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3. Structure, 24, 2016
5IHL	STRUCTURE OF THE EXTRACELLULAR DOMAIN OF THE CD40 IN COMPLEX WITH 3H56-5 DAB 分子名称: 3H56-5 domain antibody (dAb), SULFATE ION, Tumor necrosis factor receptor superfamily member 5 著者 Sheriff, S. 登録日 2016-02-29 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope. J.Mol.Biol., 428, 2016
5DMJ	Structure of the extracellular domain of the CD40 in complex with 3H56-5 DAB 分子名称: 3H65-5 domain antibody (dAb), POTASSIUM ION, Tumor necrosis factor receptor superfamily member 5 著者 Sheriff, S. 登録日 2015-09-08 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope. J.Mol.Biol., 428, 2016
5DMI	Structure of the extracellular domain of the CD40 in complex with CHI220 FAB 分子名称: Chi220 Fab heavy chain, Chi220 Fab light chain, SULFATE ION, ... 著者 Sheriff, S. 登録日 2015-09-08 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.69 Å) 主引用文献 Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope. J.Mol.Biol., 428, 2016
5CIR	Crystal structure of death receptor 4 (DR4; TNFFRSF10A) bound to TRAIL (TNFSF10) 分子名称: CHLORIDE ION, Tumor necrosis factor ligand superfamily member 10, Tumor necrosis factor receptor superfamily member 10A, ... 著者 Sheriff, S. 登録日 2015-07-13 公開日 2017-01-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex. Acta Crystallogr F Struct Biol Commun, 71, 2015

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