PDB: 278 件ウェブページステータス検索Chemie searchBIRD

---

7O6R	Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with 1H-Indazole 分子名称: 1H-indazole, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... 著者 Zehe, M, Grimm, C, Sotriffer, C. 登録日 2021-04-12 公開日 2022-05-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. Acs Chem.Biol., 2024
7SQC	Ciliary C1 central pair apparatus isolated from Chlamydomonas reinhardtii 分子名称: ADENOSINE-5'-DIPHOSPHATE, CPC1, Calmodulin, ... 著者 Gui, M, Wang, X, Dutcher, S.K, Brown, A, Zhang, R. 登録日 2021-11-05 公開日 2022-04-13 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Ciliary central apparatus structure reveals mechanisms of microtubule patterning. Nat.Struct.Mol.Biol., 29, 2022
7Q4R	Crystal structure of human HSP72-NBD in complex with fragment 1 分子名称: 4-(4-phenyl-1,3-thiazol-2-yl)piperazine-1-carboxamide, Heat shock 70 kDa protein 1A, MAGNESIUM ION, ... 著者 Le Bihan, Y.V, Westwood, I.M, van Montfort, R.L.M. 登録日 2021-11-02 公開日 2022-02-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Discovery and Characterization of a Cryptic Secondary Binding Site in the Molecular Chaperone HSP70. Molecules, 27, 2022
7OLC	Thermophilic eukaryotic 80S ribosome at idle POST state 分子名称: 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... 著者 Kisonaite, M, Wild, K, Sinning, I. 登録日 2021-05-19 公開日 2022-01-26 最終更新日 2022-04-06 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
7N1R	A novel and unique ATP hydrolysis to AMP by a human Hsp70 BiP 分子名称: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, Endoplasmic reticulum chaperone BiP, ... 著者 Yang, J, Musayev, F, Liu, Q. 登録日 2021-05-28 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 A novel and unique ATP hydrolysis to AMP by a human Hsp70 Binding immunoglobin protein (BiP). Protein Sci., 31, 2022
7KW7	Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR 分子名称: ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ... 著者 Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A. 登録日 2020-11-30 公開日 2021-12-08 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.57 Å) 主引用文献 Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism. Nature, 601, 2022
7KRW	Stimulating state of near full-length Hsp70 DnaK fused with a substrate peptide 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK fused with substrate peptide 著者 Wang, W, Hendrickson, W.A. 登録日 2020-11-20 公開日 2021-09-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (7.7 Å) 主引用文献 Conformational equilibria in allosteric control of Hsp70 chaperones. Mol.Cell, 81, 2021
7KO2	Restraining state of near full-length Hsp70 DnaK 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, MAGNESIUM ION, ... 著者 Wang, W, Hendrickson, W.A. 登録日 2020-11-06 公開日 2021-09-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Conformational equilibria in allosteric control of Hsp70 chaperones. Mol.Cell, 81, 2021
7KRU	Stimulating state of a truncated Hsp70 DnaK fused with a substrate peptide 分子名称: 1,3-PROPANDIOL, ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK fused with substrate peptide, ... 著者 Wang, W, Hendrickson, W.A. 登録日 2020-11-20 公開日 2021-09-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Conformational equilibria in allosteric control of Hsp70 chaperones. Mol.Cell, 81, 2021
7KRV	Stimulating state of disulfide-bridged Hsp70 DnaK 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK fused with substrate peptide, MAGNESIUM ION, ... 著者 Wang, W, Hendrickson, W.A. 登録日 2020-11-20 公開日 2021-09-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Conformational equilibria in allosteric control of Hsp70 chaperones. Mol.Cell, 81, 2021
7KRT	Restraining state of a truncated Hsp70 DnaK 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, MAGNESIUM ION 著者 Wang, W, Hendrickson, W.A. 登録日 2020-11-20 公開日 2021-09-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Conformational equilibria in allosteric control of Hsp70 chaperones. Mol.Cell, 81, 2021
7P31	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 分子名称: 4-IODOPYRAZOLE, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... 著者 Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. 登録日 2021-07-06 公開日 2021-07-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with small molecule ligands To Be Published
7B7Z	DeAMPylation complex of monomeric FICD and AMPylated BiP (state 1) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE MONOPHOSPHATE, Endoplasmic reticulum chaperone BiP, ... 著者 Perera, L.A, Ron, D. 登録日 2020-12-12 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD. Nat Commun, 12, 2021
7B80	DeAMPylation complex of monomeric FICD and AMPylated BiP (state 2) 分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... 著者 Perera, L.A, Ron, D. 登録日 2020-12-12 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD. Nat Commun, 12, 2021
7N6M	Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide RQKPLLGLSR 分子名称: Alkaline phosphatase peptide, Chaperone protein DnaK, SULFATE ION 著者 Jansen, R.M, Ozden, C, Gierasch, L.M, Garman, S.C. 登録日 2021-06-08 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Selective promiscuity in the binding of E. coli Hsp70 to an unfolded protein. Proc.Natl.Acad.Sci.USA, 118, 2021
7N6K	Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide RALALLPLSR 分子名称: Alkaline phosphatase peptide, Chaperone protein DnaK, SULFATE ION 著者 Jansen, R.M, Ozden, C, Gierasch, L.M, Garman, S.C. 登録日 2021-06-08 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Selective promiscuity in the binding of E. coli Hsp70 to an unfolded protein. Proc.Natl.Acad.Sci.USA, 118, 2021
7N6J	Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide RKQSTIALALLPLLFTPRR 分子名称: Alkaline phosphatase peptide, Chaperone protein DnaK, SULFATE ION 著者 Jansen, R.M, Ozden, C, Gierasch, L.M, Garman, S.C. 登録日 2021-06-08 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Selective promiscuity in the binding of E. coli Hsp70 to an unfolded protein. Proc.Natl.Acad.Sci.USA, 118, 2021
7N6L	Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide EANQQKPLLGLFADG 分子名称: Alkaline phosphatase peptide, Chaperone protein DnaK, GLYCEROL, ... 著者 Jansen, R.M, Ozden, C, Gierasch, L.M, Garman, S.C. 登録日 2021-06-08 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Selective promiscuity in the binding of E. coli Hsp70 to an unfolded protein. Proc.Natl.Acad.Sci.USA, 118, 2021
7OOH	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 分子名称: 4-IODOPYRAZOLE, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... 著者 Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. 登録日 2021-05-27 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 To Be Published
7OOG	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023823 分子名称: 4-bromanylpyridin-2-amine, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... 著者 Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. 登録日 2021-05-27 公開日 2021-06-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023823 To Be Published
7OOE	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z321318226 分子名称: AMP PHOSPHORAMIDATE, CHLORIDE ION, GLYCEROL, ... 著者 Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. 登録日 2021-05-27 公開日 2021-06-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.369 Å) 主引用文献 Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
6W6E	The Mycobacterium tuberculosis ClpB disaggregase hexamer structure with a locally refined ClpB middle domain and a DnaK nucleotide binding domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, Chaperone protein DnaK, ... 著者 Yin, Y, Li, H. 登録日 2020-03-16 公開日 2021-05-26 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
7L6N	The Mycobacterium tuberculosis ClpB disaggregase hexamer structure with three locally refined ClpB middle domains and three DnaK nucleotide binding domains 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, Chaperone protein DnaK, ... 著者 Yin, Y.Y, Feng, X, Li, H. 登録日 2020-12-23 公開日 2021-05-26 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
7KZI	Intermediate state (QQQ) of near full-length DnaK alternatively fused with a substrate peptide 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Chaperone protein DnaK fused with substrate peptide,Chaperone protein DnaK fused with substrate peptide, ... 著者 Wang, W, Hendrickson, W.A. 登録日 2020-12-10 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Intermediates in allosteric equilibria of DnaK-ATP interactions with substrate peptides Acta Crystallogr.,Sect.D, 77, 2021
7KZU	Quasi-intermediate state (Q) of a truncated Hsp70 DnaK fused with a substrate peptide 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK fused with substrate peptide,Chaperone protein DnaK fused with substrate peptide, GLYCEROL, ... 著者 Wang, W, Hendrickson, W.A. 登録日 2020-12-10 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Intermediates in allosteric equilibria of DnaK-ATP interactions with substrate peptides Acta Crystallogr.,Sect.D, 77, 2021

<123456789101112>