7B80

DeAMPylation complex of monomeric FICD and AMPylated BiP (state 2)

Summary for 7B80

• Entry DOI: 10.2210/pdb7b80/pdb
• Descriptor: Endoplasmic reticulum chaperone BiP, Protein adenylyltransferase FICD, ADENOSINE MONOPHOSPHATE, ... (9 entities in total)
• Functional Keywords: ficd, fic, hype, bip, grp78, ampylation, deampylation, deampylase, er stress, complex, adenylation, adenylylation, hsp70, chaperone, transferase, hydrolase
• Biological source: Cricetulus griseus (Chinese hamster); More
• Total number of polymer chains: 2
• Total formula weight: 98400.13

Authors

Perera, L.A.,Ron, D. (deposition date: 2020-12-12, release date: 2021-07-07, Last modification date: 2024-01-31)

• Primary citation: Perera, L.A.,Preissler, S.,Zaccai, N.R.,Prevost, S.,Devos, J.M.,Haertlein, M.,Ron, D.; Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD.; Nat Commun, 12:5004-5004, 2021; PubMed: 34408154; DOI: 10.1038/s41467-021-25076-7

Experimental method

X-RAY DIFFRACTION (1.87 Å)