7Q4R
Crystal structure of human HSP72-NBD in complex with fragment 1
Summary for 7Q4R
| Entry DOI | 10.2210/pdb7q4r/pdb |
| Descriptor | Heat shock 70 kDa protein 1A, MAGNESIUM ION, 4-(4-phenyl-1,3-thiazol-2-yl)piperazine-1-carboxamide, ... (5 entities in total) |
| Functional Keywords | inhibitor, chaperone, atpase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 43603.55 |
| Authors | Le Bihan, Y.V.,Westwood, I.M.,van Montfort, R.L.M. (deposition date: 2021-11-02, release date: 2022-02-02, Last modification date: 2024-01-31) |
| Primary citation | O'Connor, S.,Le Bihan, Y.V.,Westwood, I.M.,Liu, M.,Mak, O.W.,Zazeri, G.,Povinelli, A.P.R.,Jones, A.M.,van Montfort, R.,Reynisson, J.,Collins, I. Discovery and Characterization of a Cryptic Secondary Binding Site in the Molecular Chaperone HSP70. Molecules, 27:-, 2022 Cited by PubMed: 35164081DOI: 10.3390/molecules27030817 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
Download full validation report
