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5YD8
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BU of 5yd8 by Molmil
Crystal structure of human PCNA in complex with APIM of human ZRANB3
分子名称: Proliferating cell nuclear antigen, ZRANB3
著者Hashimoto, H, Tagata, R.
登録日2017-09-12
公開日2018-04-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of proliferating cell nuclear antigen (PCNA) bound to an APIM peptide reveals the universality of PCNA interaction.
Acta Crystallogr.,Sect.F, 74, 2018
5YCO
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BU of 5yco by Molmil
Complex structure of PCNA with UHRF2
分子名称: E3 ubiquitin-protein ligase UHRF2, GLYCEROL, Proliferating cell nuclear antigen, ...
著者Wu, M, Chen, W, Hang, T, Wang, C, Zhang, X, Zang, J.
登録日2017-09-07
公開日2017-11-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Structure insights into the molecular mechanism of the interaction between UHRF2 and PCNA.
Biochem. Biophys. Res. Commun., 494, 2017
1JEY
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BU of 1jey by Molmil
Crystal Structure of the Ku heterodimer bound to DNA
分子名称: DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), Ku70, ...
著者Walker, J.R, Corpina, R.A, Goldberg, J.
登録日2001-06-19
公開日2001-08-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair.
Nature, 412, 2001
7RRO
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BU of 7rro by Molmil
Structure of the 48-nm repeat doublet microtubule from bovine tracheal cilia
分子名称: Armadillo repeat containing 4, Chromosome 3 C1orf194 homolog, Cilia and flagella associated protein 161, ...
著者Gui, M, Anderson, J.R, Botsch, J.J, Meleppattu, S, Singh, S.K, Zhang, Q, Brown, A.
登録日2021-08-10
公開日2021-10-27
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献De novo identification of mammalian ciliary motility proteins using cryo-EM.
Cell, 184, 2021
1CXZ
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BU of 1cxz by Molmil
CRYSTAL STRUCTURE OF HUMAN RHOA COMPLEXED WITH THE EFFECTOR DOMAIN OF THE PROTEIN KINASE PKN/PRK1
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, PROTEIN (HIS-TAGGED TRANSFORMING PROTEIN RHOA(0-181)), ...
著者Maesaki, R, Ihara, K, Shimizu, T, Kuroda, S, Kaibuchi, K, Hakoshima, T.
登録日1999-08-31
公開日1999-10-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1.
Mol.Cell, 4, 1999
7Y5K
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BU of 7y5k by Molmil
Crystal structure of human CAF-1 core complex in spacegroup C2221
分子名称: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ...
著者Liu, C.P, Wang, M.Z, Xu, R.M.
登録日2022-06-17
公開日2023-08-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.48 Å)
主引用文献Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
7Y5O
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BU of 7y5o by Molmil
Crystal structure of human CAF-1 core complex in spacegroup P21
分子名称: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ...
著者Liu, C.P, Wang, M.Z, Xu, R.M.
登録日2022-06-17
公開日2023-08-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.57 Å)
主引用文献Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
7Y5L
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BU of 7y5l by Molmil
Crystal structure of human CAF-1 core complex in spacegroup C2
分子名称: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ...
著者Liu, C.P, Wang, M.Z, Xu, R.M.
登録日2022-06-17
公開日2023-08-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
8UO5
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BU of 8uo5 by Molmil
Protein Phosphatase 2A B55 subunit in complex with IER5
分子名称: FE (III) ION, Immediate early response gene 5 protein, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, ...
著者Jones, D.T.D, Cao, R, Rawson, S.D, Blacklow, S.C.
登録日2023-10-19
公開日2025-03-26
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Protein Phosphatase 2A B55 subunit in complex with IER5
To Be Published
8OWO
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BU of 8owo by Molmil
SMYD3 in complex with fragment FL01507
分子名称: 3-oxidanylbenzenecarbonitrile, GLYCEROL, Histone-lysine N-methyltransferase SMYD3, ...
著者Lund, B.A, Cederfelt, D, Dobritzsch, D.
登録日2023-04-28
公開日2023-08-30
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening.
Rsc Med Chem, 15, 2024
2R1V
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BU of 2r1v by Molmil
Norepinephrine quinone conjugation to DJ-1
分子名称: DJ-1
著者Zhongtao, Z, Yue, F.
登録日2007-08-23
公開日2008-08-26
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献DJ-1 activation by catechol quinone conjugation
To be Published
2R1T
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BU of 2r1t by Molmil
dopamine quinone conjugation to DJ-1
分子名称: DJ-1
著者Zhongtao, Z, Yue, F.
登録日2007-08-23
公開日2008-08-26
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献DJ-1 is a proisopeptidase
To be Published
7RPW
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BU of 7rpw by Molmil
Archaeal DNA ligase and heterotrimeric PCNA in complex with adenylated DNA
分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ...
著者Sverzhinsky, A, Pascal, J.M.
登録日2021-08-04
公開日2021-11-17
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.38 Å)
主引用文献Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase.
Structure, 30, 2022
7RPO
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BU of 7rpo by Molmil
Archaeal DNA ligase and heterotrimeric PCNA in complex with non-ligatable DNA
分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ...
著者Sverzhinsky, A, Pascal, J.M.
登録日2021-08-03
公開日2021-11-17
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase.
Structure, 30, 2022
7RPX
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BU of 7rpx by Molmil
Archaeal DNA ligase and heterotrimeric PCNA in complex with end-joined DNA
分子名称: DNA ligase, DNA polymerase sliding clamp 1, DNA polymerase sliding clamp 2, ...
著者Sverzhinsky, A, Pascal, J.M.
登録日2021-08-04
公開日2021-11-17
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase.
Structure, 30, 2022
2G9A
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BU of 2g9a by Molmil
Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5
分子名称: Histone H3, WD-repeat protein 5
著者Chai, J, Han, Z, Wang, H, Shen, Y.
登録日2006-03-06
公開日2006-09-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5
To be published
2G99
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BU of 2g99 by Molmil
Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5
分子名称: Histone H3, WD-repeat protein 5
著者Chai, J, Han, Z, Wang, H, Shen, Y.
登録日2006-03-06
公開日2006-09-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5
To be published
7OHA
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BU of 7oha by Molmil
nucleosome with TBP and TFIIA bound at SHL +2
分子名称: DNA (122-MER), Histone H2A, Histone H2B 1.1, ...
著者Wang, H, Cramer, P.
登録日2021-05-09
公開日2021-07-28
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7XZZ
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BU of 7xzz by Molmil
Cryo-EM structure of the nucleosome in complex with p53
分子名称: Cellular tumor antigen p53, DNA (169-MER), Histone H2A type 1-B/E, ...
著者Nishimura, M, Nozawa, K, Takizawa, Y, Kurumizaka, H.
登録日2022-06-03
公開日2022-10-12
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Structural basis for p53 binding to its nucleosomal target DNA sequence.
Pnas Nexus, 1, 2022
5EAP
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BU of 5eap by Molmil
Crystal structure of human WDR5 in complex with compound 9e
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
著者DONG, A, DOMBROVSKI, L, SMIL, D, GETLIK, M, BOLSHAN, Y, WALKER, J.R, SENISTERRA, G, PODA, G, AL-AWAR, R, SCHAPIRA, M, VEDADI, M, Bountra, C, Edwards, A.M, Arrowsmith, C.H, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC)
登録日2015-10-16
公開日2015-11-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structure-Based Optimization of a Small Molecule Antagonist of the Interaction Between WD Repeat-Containing Protein 5 (WDR5) and Mixed-Lineage Leukemia 1 (MLL1).
J. Med. Chem., 59, 2016
5EAR
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BU of 5ear by Molmil
Crystal structure of human WDR5 in complex with compound 9d
分子名称: 1,2-ETHANEDIOL, N-[5-(2,3-dihydro-1-benzofuran-7-yl)-2-(4-methylpiperazin-1-yl)phenyl]-3-methylbenzamide, SULFATE ION, ...
著者DONG, A, DOMBROVSKI, L, SMIL, D, GETLIK, M, BOLSHAN, Y, WALKER, J.R, SENISTERRA, G, PODA, G, AL-AWAR, R, SCHAPIRA, M, VEDADI, M, Bountra, C, Edwards, A.M, Arrowsmith, C.H, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC)
登録日2015-10-16
公開日2015-11-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-Based Optimization of a Small Molecule Antagonist of the Interaction Between WD Repeat-Containing Protein 5 (WDR5) and Mixed-Lineage Leukemia 1 (MLL1).
J. Med. Chem., 59, 2016
3C99
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BU of 3c99 by Molmil
Structural Basis of Histone H4 Recognition by p55
分子名称: CADMIUM ION, Chromatin assembly factor 1 p55 subunit
著者Song, J.J, Garlick, J.D, Kingston, R.E.
登録日2008-02-15
公開日2008-05-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of histone H4 recognition by p55.
Genes Dev., 22, 2008
4LL4
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BU of 4ll4 by Molmil
The structure of the TRX and TXNIP complex
分子名称: Thioredoxin, Thioredoxin-interacting protein
著者Hwang, J, Kim, M.H.
登録日2013-07-09
公開日2014-02-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
1ETK
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BU of 1etk by Molmil
THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68A
分子名称: FACTOR FOR INVERSION STIMULATION
著者Cheng, Y.S, Yang, W.Z, Johnson, R.C, Yuan, H.S.
登録日2000-04-13
公開日2000-10-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analysis of the transcriptional activation on Fis: crystal structures of six Fis mutants with different activation properties.
J.Mol.Biol., 302, 2000
1ETY
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BU of 1ety by Molmil
THE CRYSTAL STRUCTURE OF E. COLI WILD-TYPE FIS
分子名称: FACTOR FOR INVERSION STIMULATION
著者Cheng, Y.S, Yang, W.Z, Johnson, R.C, Yuan, H.S.
登録日2000-04-13
公開日2000-10-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis of the transcriptional activation on Fis: crystal structures of six Fis mutants with different activation properties.
J.Mol.Biol., 302, 2000

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