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3MVG
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BU of 3mvg by Molmil
Native structure of IRIP, a type I ribosome inactivating protein from Iris hollandica var. at 1.25 A
分子名称: GLYCEROL, Ribosome inactivating type 1 protein, SULFATE ION
著者Meyer, A, Weber, W, Singh, T.P, Betzel, C.
登録日2010-05-04
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Native structure of IRIP, a type I ribosome inactivating protein from Iris hollandica var. at 1.25 A
to be published
3MX6
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BU of 3mx6 by Molmil
Crystal structure of methionine aminopeptidase from Rickettsia prowazekii bound to methionine
分子名称: MANGANESE (II) ION, METHIONINE, Methionine aminopeptidase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-05-06
公開日2010-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents.
Bioorg.Med.Chem., 25, 2017
3MXU
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BU of 3mxu by Molmil
Crystal structure of glycine cleavage system protein H from Bartonella henselae
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Glycine cleavage system H protein, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-05-07
公開日2010-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of glycine cleavage system protein H from Bartonella henselae
To be Published
3N5O
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BU of 3n5o by Molmil
Crystal structure of putative glutathione transferase from Coccidioides immitis bound to glutathione
分子名称: GLUTATHIONE, SULFATE ION, glutathione transferase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-05-25
公開日2010-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of a putative zeta-class glutathione S-transferase from the pathogenic fungus Coccidioides immitis.
Acta Crystallogr.,Sect.F, 67, 2011
3NCB
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BU of 3ncb by Molmil
A mutant human Prolactin receptor antagonist H180A in complex with the extracellular domain of the human prolactin receptor
分子名称: CARBONATE ION, CHLORIDE ION, Prolactin, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-06-04
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3NCF
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BU of 3ncf by Molmil
A mutant human Prolactin receptor antagonist H30A in complex with the mutant extracellular domain H188A of the human prolactin receptor
分子名称: CHLORIDE ION, Prolactin, Prolactin receptor, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-06-04
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3MBM
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BU of 3mbm by Molmil
Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytosine and FoL fragment 717, imidazo[2,1-b][1,3]thiazol-6-ylmethanol
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 6-AMINOPYRIMIDIN-2(1H)-ONE, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-03-25
公開日2010-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3MF4
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BU of 3mf4 by Molmil
Crystal structure of putative two-component system response regulator/ggdef domain protein
分子名称: MAGNESIUM ION, Two-component system response regulator/GGDEF domain protein
著者Malashkevich, V.N, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-04-01
公開日2010-04-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of putative two-component system response regulator/ggdef domain protein
To be Published
2H7Z
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BU of 2h7z by Molmil
Crystal structure of irditoxin
分子名称: Irditoxin subunit A, Irditoxin subunit B
著者Pawlak, J, Kini, R.M, Stura, E.A, Le Du, M.H.
登録日2006-06-06
公開日2006-08-29
最終更新日2011-10-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity.
Faseb J., 23, 2009
3N74
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BU of 3n74 by Molmil
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from Brucella melitensis
分子名称: 3-ketoacyl-(acyl-carrier-protein) reductase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-05-26
公開日2010-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from Brucella melitensis
TO BE PUBLISHED
3NF4
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BU of 3nf4 by Molmil
Crystal structure of acyl-CoA dehydrogenase from Mycobacterium thermoresistibile bound to flavin adenine dinucleotide
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, SODIUM ION, acyl-CoA dehydrogenase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-06-09
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3N7T
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BU of 3n7t by Molmil
Crystal structure of a macrophage binding protein from Coccidioides immitis
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Macrophage binding protein, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-05-27
公開日2010-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of a macrophage binding protein from Coccidioides immitis
TO BE PUBLISHED
3NCE
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BU of 3nce by Molmil
A mutant human Prolactin receptor antagonist H27A in complex with the mutant extracellular domain H188A of the human prolactin receptor
分子名称: CARBONATE ION, CHLORIDE ION, Prolactin, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-06-04
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
4GIG
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BU of 4gig by Molmil
crystal structure of T69A mutant of trapped Dnae intein precursor
分子名称: DNA polymerase III subunit alpha, SULFATE ION
著者Van Roey, P.
登録日2012-08-08
公開日2013-03-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A conserved threonine spring-loads precursor for intein splicing.
Protein Sci., 22, 2013
4G69
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BU of 4g69 by Molmil
Structure of the Human Discs Large 1 PDZ2 - Adenomatous Polyposis Coli Cytoskeletal Polarity Complex
分子名称: Adenomatous polyposis coli protein, Disks large homolog 1
著者Slep, K.C.
登録日2012-07-18
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the Human Discs Large 1 PDZ2- Adenomatous Polyposis Coli Cytoskeletal Polarity Complex: Insight into Peptide Engagement and PDZ Clustering.
Plos One, 7, 2012
6X88
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BU of 6x88 by Molmil
PDE6 chicken GAF domain
分子名称: Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
著者Ke, H.
登録日2020-06-01
公開日2020-11-04
実験手法X-RAY DIFFRACTION (3.1997447 Å)
主引用文献Structural Analysis of the Regulatory GAF Domains of cGMP Phosphodiesterase Elucidates the Allosteric Communication Pathway.
J.Mol.Biol., 432, 2020
5A63
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BU of 5a63 by Molmil
Cryo-EM structure of the human gamma-secretase complex at 3.4 angstrom resolution.
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Bai, X, Yan, C, Yang, G, Lu, P, Ma, D, Sun, L, Zhou, R, Scheres, S.H.W, Shi, Y.
登録日2015-06-24
公開日2015-08-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献An Atomic Structure of Human Gamma-Secretase
Nature, 525, 2015
4GOY
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BU of 4goy by Molmil
The crystal structure of human fascin 1 K41A mutant
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BROMIDE ION, CHLORIDE ION, ...
著者Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y.
登録日2012-08-20
公開日2012-11-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular mechanism of fascin function in filopodial formation.
J.Biol.Chem., 288, 2013
8T1C
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BU of 8t1c by Molmil
Cryo-EM structure of human TRPV4 ankyrin repeat domain in complex with GTPase RhoA
分子名称: GUANOSINE-5'-DIPHOSPHATE, Transforming protein RhoA, Transient receptor potential cation channel subfamily V member 4-Enhanced green fluorescent protein chimera
著者Nadezhdin, K.D, Talyzina, I.A, Neuberger, A, Sobolevsky, A.I.
登録日2023-06-02
公開日2023-07-05
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Structure of human TRPV4 in complex with GTPase RhoA.
Nat Commun, 14, 2023
6FUY
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BU of 6fuy by Molmil
Crystal structure of human full-length vinculin-T12-A974K (residues 1-1066)
分子名称: CALCIUM ION, Vinculin
著者Chorev, D.S, Volberg, T, Livne, A, Eisenstein, M, Martins, B, Kam, Z, Jockusch, B.M, Medalia, O, Sharon, M, Geiger, B.
登録日2018-02-28
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conformational states during vinculin unlocking differentially regulate focal adhesion properties.
Sci Rep, 8, 2018
6UDN
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BU of 6udn by Molmil
Crystal Structure of a Self-Assembling DNA Scaffold Containing TA Sticky Ends and Rhombohedral Symmetry
分子名称: ARSENIC, DNA (5'-D(*TP*AP*CP*TP*GP*AP*CP*TP*CP*AP*TP*GP*CP*TP*CP*AP*TP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*AP*TP*CP*AP*GP*AP*TP*G)-3'), ...
著者Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H.
登録日2019-09-19
公開日2020-09-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail.
Angew.Chem.Int.Ed.Engl., 59, 2020
6U40
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Crystal Structure of a Self-Assembling DNA Crystal Scaffold with Rhombohedral Symmetry
分子名称: CACODYLATE ION, DNA (5'-D(*CP*AP*CP*TP*GP*AP*CP*TP*CP*AP*TP*GP*CP*TP*CP*AP*TP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*AP*GP*AP*TP*G)-3'), ...
著者Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H.
登録日2019-08-22
公開日2020-08-26
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail.
Angew.Chem.Int.Ed.Engl., 59, 2020
6UEF
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BU of 6uef by Molmil
Crystal Structure of a Self-Assembling DNA Scaffold Containing Sequence Modifications to Attempt to Disrupt Crystal Contacts in a Rhombohedral Lattice.
分子名称: DNA (5'-D(*CP*AP*AP*TP*GP*AP*CP*TP*CP*AP*TP*GP*CP*TP*CP*AP*TP*CP*GP*GP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*GP*AP*TP*G)-3'), DNA (5'-D(P*AP*GP*CP*AP*TP*GP*A)-3'), ...
著者Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H.
登録日2019-09-20
公開日2020-09-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail.
Angew.Chem.Int.Ed.Engl., 59, 2020
3LW8
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BU of 3lw8 by Molmil
Shigella IpgB2 in complex with human RhoA, GDP and Mg2+ (complex A)
分子名称: GUANOSINE-5'-DIPHOSPHATE, IpgB2, MAGNESIUM ION, ...
著者Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W.
登録日2010-02-23
公開日2010-03-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry
J.Biol.Chem., 285, 2010
1N2D
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BU of 1n2d by Molmil
Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin
分子名称: IQ2 AND IQ3 MOTIFS FROM MYO2P, A CLASS V MYOSIN, Myosin Light Chain
著者Terrak, M, Wu, G, Stafford, W.F, Lu, R.C, Dominguez, R.
登録日2002-10-22
公開日2003-11-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the light chain-binding domain of myosin V.
Proc.Natl.Acad.Sci.USA, 102, 2005

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