8T1C

Cryo-EM structure of human TRPV4 ankyrin repeat domain in complex with GTPase RhoA

Summary for 8T1C

• Entry DOI: 10.2210/pdb8t1c/pdb
• Related: 8T1B
• EMDB information: 40958 40959
• Descriptor: Transient receptor potential cation channel subfamily V member 4-Enhanced green fluorescent protein chimera, Transforming protein RhoA, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: transient receptor potential v family member 4, trp, channel, trpv4, trp channels, membrane protein, gtpase, transforming protein rhoa, rhoa, ankyrin repeat domain, gdp, guanosine diphosphate
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 149960.30

Authors

Nadezhdin, K.D.,Talyzina, I.A.,Neuberger, A.,Sobolevsky, A.I. (deposition date: 2023-06-02, release date: 2023-07-05)

• Primary citation: Nadezhdin, K.D.,Talyzina, I.A.,Parthasarathy, A.,Neuberger, A.,Zhang, D.X.,Sobolevsky, A.I.; Structure of human TRPV4 in complex with GTPase RhoA.; Nat Commun, 14:3733-3733, 2023; PubMed: 37353478; DOI: 10.1038/s41467-023-39346-z

Experimental method

ELECTRON MICROSCOPY (3.49 Å)