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1HW9
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BU of 1hw9 by Molmil
COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH SIMVASTATIN
分子名称: ADENOSINE-5'-DIPHOSPHATE, HMG-COA REDUCTASE, Simvastatin acid
著者Istvan, E.S, Deisenhofer, J.
登録日2001-01-09
公開日2001-05-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Structural mechanism for statin inhibition of HMG-CoA reductase.
Science, 292, 2001
2FWV
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BU of 2fwv by Molmil
Crystal Structure of Rv0813
分子名称: 1,4-DIETHYLENE DIOXIDE, GLYCEROL, hypothetical protein MtubF_01000852
著者Shepard, W, Haouz, A, Grana, M, Buschiazzo, A, Betton, J.M, Cole, S.T, Alzari, P.M, Structural Proteomics in Europe (SPINE)
登録日2006-02-03
公開日2006-08-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of Rv0813c from Mycobacterium tuberculosis Reveals a New Family of Fatty Acid-Binding Protein-Like Proteins in Bacteria
J.Bacteriol., 189, 2007
6YUA
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BU of 6yua by Molmil
CO-dehydrogenase coupled to the N-terminal domain of the Acetyl-CoA synthase from Clostridium autoethanogenum isolated after tryptic digestion.
分子名称: 1,2-ETHANEDIOL, CO dehydrogenase/acetyl-CoA synthase complex, beta subunit, ...
著者Wagner, T, Lemaire, O.N.
登録日2020-04-26
公開日2020-11-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Gas channel rerouting in a primordial enzyme: Structural insights of the carbon-monoxide dehydrogenase/acetyl-CoA synthase complex from the acetogen Clostridium autoethanogenum.
Biochim Biophys Acta Bioenerg, 1862, 2020
6YTT
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BU of 6ytt by Molmil
CO-dehydrogenase/Acetyl-CoA synthase (CODH/ACS) from Clostridium autoethanogenum at 3.0-A resolution
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CO dehydrogenase/acetyl-CoA synthase complex, beta subunit, ...
著者Wagner, T, Lemaire, O.N.
登録日2020-04-24
公開日2020-11-04
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Gas channel rerouting in a primordial enzyme: Structural insights of the carbon-monoxide dehydrogenase/acetyl-CoA synthase complex from the acetogen Clostridium autoethanogenum.
Biochim Biophys Acta Bioenerg, 1862, 2020
5OOL
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BU of 5ool by Molmil
Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA
分子名称: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ...
著者Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V.
登録日2017-08-08
公開日2017-09-13
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
5CUF
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BU of 5cuf by Molmil
X-ray crystal structure of SeMet human Sestrin2
分子名称: Sestrin-2
著者Kim, H, An, S, Ro, S.-H, Lee, J.H, Cho, U.-S.
登録日2015-07-24
公開日2016-01-13
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Janus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domains.
Nat Commun, 6, 2015
6ZI7
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BU of 6zi7 by Molmil
Crystal structure of OleP-oleandolide(DEO) bound to L-rhamnose
分子名称: (3~{R},4~{S},5~{R},6~{S},7~{S},9~{S},11~{R},12~{S},13~{R},14~{R})-3,5,7,9,11,13,14-heptamethyl-4,6,12-tris(oxidanyl)-1-oxacyclotetradecane-2,10-dione, Cytochrome P-450, FORMIC ACID, ...
著者Montemiglio, L.C, Savino, C, Vallone, B, Parisi, G, Freda, I.
登録日2020-06-25
公開日2020-10-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate.
Biomolecules, 10, 2020
6ZI3
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BU of 6zi3 by Molmil
Crystal structure of OleP-6DEB bound to L-rhamnose
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, ...
著者Montemiglio, L.C, Savino, C, Vallone, B, Parisi, G, Freda, I.
登録日2020-06-24
公開日2020-10-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate.
Biomolecules, 10, 2020
6ZHZ
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BU of 6zhz by Molmil
OleP-oleandolide(DEO) in high salt crystallization conditions
分子名称: (3~{R},4~{S},5~{R},6~{S},7~{S},9~{S},11~{R},12~{S},13~{R},14~{R})-3,5,7,9,11,13,14-heptamethyl-4,6,12-tris(oxidanyl)-1-oxacyclotetradecane-2,10-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytochrome P-450, ...
著者Montemiglio, L.C, Savino, C, Vallone, B, Parisi, G, Cecchetti, C.
登録日2020-06-24
公開日2020-10-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate.
Biomolecules, 10, 2020
6ZI2
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BU of 6zi2 by Molmil
OleP-oleandolide(DEO) in low salt crystallization conditions
分子名称: (3~{R},4~{S},5~{R},6~{S},7~{S},9~{S},11~{R},12~{S},13~{R},14~{R})-3,5,7,9,11,13,14-heptamethyl-4,6,12-tris(oxidanyl)-1-oxacyclotetradecane-2,10-dione, Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE
著者Savino, C, Montemiglio, L.C, Vallone, B, Parisi, G, Cecchetti, C.
登録日2020-06-24
公開日2020-10-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate.
Biomolecules, 10, 2020
5DIQ
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BU of 5diq by Molmil
Crystal structure of human FPPS in complex with salicylic acid derivative 3a
分子名称: 2-(naphthalen-1-ylmethoxy)benzoic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ...
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-01
公開日2015-09-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5DJP
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BU of 5djp by Molmil
Crystal structure of human FPPS in complex with biaryl compound 5
分子名称: 4-(naphthalen-1-yl)-1H-indole-2-carboxylic acid, Farnesyl pyrophosphate synthase, PHOSPHATE ION
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-02
公開日2015-09-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5DJV
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BU of 5djv by Molmil
Crystal structure of human FPPS in complex with biaryl compound 8e
分子名称: 8-(naphthalen-1-yl)-6-(1H-pyrrol-2-yl)quinoline-2-carboxylic acid, Farnesyl pyrophosphate synthase
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-02
公開日2015-10-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5DJR
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BU of 5djr by Molmil
Crystal structure of human FPPS in complex with biaryl compound 6
分子名称: 1H,1'H-4,4'-biindole-2-carboxylic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ...
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-02
公開日2015-09-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
2MDI
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BU of 2mdi by Molmil
Solution structure of the PP2WW mutant (KPP2WW) of HYPB
分子名称: Histone-lysine N-methyltransferase SETD2
著者Gao, Y.G, Hu, H.Y.
登録日2013-09-10
公開日2014-09-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin.
Structure, 22, 2014
2LXL
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BU of 2lxl by Molmil
Lip5(mit)2
分子名称: Vacuolar protein sorting-associated protein VTA1 homolog
著者Skalicky, J.J, Sundquist, W.I.
登録日2012-08-29
公開日2012-11-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Interactions of the Human LIP5 Regulatory Protein with Endosomal Sorting Complexes Required for Transport.
J.Biol.Chem., 287, 2012
2LXM
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BU of 2lxm by Molmil
Lip5-chmp5
分子名称: Charged multivesicular body protein 5, Vacuolar protein sorting-associated protein VTA1 homolog
著者Skalicky, J.J, Sundquist, W.I.
登録日2012-08-29
公開日2012-11-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Interactions of the Human LIP5 Regulatory Protein with Endosomal Sorting Complexes Required for Transport.
J.Biol.Chem., 287, 2012
2MDJ
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BU of 2mdj by Molmil
Solution structure of WW domain with polyproline stretch (PP2WW) of HYPB
分子名称: Histone-lysine N-methyltransferase SETD2
著者Gao, Y, Hu, H.
登録日2013-09-11
公開日2014-09-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin
Structure, 22, 2014
2MDC
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BU of 2mdc by Molmil
Solution structure of the WW domain of HYPB
分子名称: Histone-lysine N-methyltransferase SETD2
著者Gao, Y.G.
登録日2013-09-10
公開日2014-09-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin
Structure, 22, 2014
6J8Y
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BU of 6j8y by Molmil
Crystal structure of the human RAD9-HUS1-RAD1-RHINO complex
分子名称: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1, ...
著者Hara, K, Iida, N, Sakurai, H, Hashimoto, H.
登録日2019-01-21
公開日2019-12-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the RAD9-RAD1-HUS1 checkpoint clamp bound to RHINO sheds light on the other side of the DNA clamp.
J.Biol.Chem., 295, 2020
2N1O
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BU of 2n1o by Molmil
PIN1 WW domain in complex with a phosphorylated CPEB1 derived peptide
分子名称: Cytoplasmic polyadenylation element-binding protein 1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Schelhorn, C, Macias, M, Martin-Malpartida, P.
登録日2015-04-13
公開日2015-10-28
実験手法SOLUTION NMR
主引用文献Structural Analysis of the Pin1-CPEB1 interaction and its potential role in CPEB1 degradation.
Sci Rep, 5, 2015
2NZ0
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BU of 2nz0 by Molmil
Crystal structure of potassium channel Kv4.3 in complex with its regulatory subunit KChIP1
分子名称: CALCIUM ION, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 3, ...
著者Wang, H, Yan, Y, Shen, Y, Chen, L, Wang, K.
登録日2006-11-22
公開日2006-12-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for modulation of Kv4 K(+) channels by auxiliary KChIP subunits.
Nat.Neurosci., 10, 2007
2Q5A
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BU of 2q5a by Molmil
human Pin1 bound to L-PEPTIDE
分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE, Five residue peptide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Noel, J.P, Zhang, Y.
登録日2007-05-31
公開日2007-06-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for high-affinity peptide inhibition of human Pin1.
Acs Chem.Biol., 2, 2007
2FIC
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BU of 2fic by Molmil
The crystal structure of the BAR domain from human Bin1/Amphiphysin II and its implications for molecular recognition
分子名称: Myc box-dependent-interacting protein 1, XENON
著者Casal, E, Federici, L, Zhang, W, Fernandez-Recio, J, Priego, E.M, Miguel, R.N, Duhadaway, J.B, Prendergast, G.C, Luisi, B.F, Laue, E.D.
登録日2005-12-29
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The Crystal Structure of the BAR Domain from Human Bin1/Amphiphysin II and Its Implications for Molecular Recognition
Biochemistry, 45, 2006
6ZE5
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BU of 6ze5 by Molmil
FAD-dependent oxidoreductase from Chaetomium thermophilum in complex with fragment 2-(1H-indol-3-yl)-N-[(1-methyl-1H-pyrrol-2-yl)methyl]ethanamine
分子名称: 2-(1H-indol-3-yl)-N-[(1-methyl-1H-pyrrol-2-yl)methyl]ethanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Svecova, L, Skalova, T, Kolenko, P, Koval, T, Oestergaard, L.H, Dohnalek, J.
登録日2020-06-16
公開日2021-05-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystallographic fragment screening-based study of a novel FAD-dependent oxidoreductase from Chaetomium thermophilum.
Acta Crystallogr D Struct Biol, 77, 2021

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