6ZI2

OleP-oleandolide(DEO) in low salt crystallization conditions

Summary for 6ZI2

• Entry DOI: 10.2210/pdb6zi2/pdb
• Related: 6ZHZ
• Descriptor: Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE, (3~{R},4~{S},5~{R},6~{S},7~{S},9~{S},11~{R},12~{S},13~{R},14~{R})-3,5,7,9,11,13,14-heptamethyl-4,6,12-tris(oxidanyl)-1-oxacyclotetradecane-2,10-dione, ... (4 entities in total)
• Functional Keywords: cytochrome p450, 8.8a-deoxyoleandolide monooxygenase, 8.8a-deoxyoleandolide, oxidoreductase
• Biological source: Streptomyces antibioticus
• Total number of polymer chains: 9
• Total formula weight: 414009.48

Authors

Savino, C.,Montemiglio, L.C.,Vallone, B.,Parisi, G.,Cecchetti, C. (deposition date: 2020-06-24, release date: 2020-10-21, Last modification date: 2024-01-31)

• Primary citation: Parisi, G.,Freda, I.,Exertier, C.,Cecchetti, C.,Gugole, E.,Cerutti, G.,D'Auria, L.,Macone, A.,Vallone, B.,Savino, C.,Montemiglio, L.C.; Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate.; Biomolecules, 10:-, 2020; PubMed: 33036250; DOI: 10.3390/biom10101411

Experimental method

X-RAY DIFFRACTION (2.93 Å)