PDB: 245663 件ウェブページステータス検索Chemie searchBIRD

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6XRX	Crystal structure of the mosquito protein AZ1 as an MBP fusion 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Maltose/maltodextrin-binding periplasmic protein, ... 著者 Pedersen, L.C, Mueller, G.A, Foo, A.C.Y. 登録日 2020-07-14 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The mosquito protein AEG12 displays both cytolytic and antiviral properties via a common lipid transfer mechanism. Proc.Natl.Acad.Sci.USA, 118, 2021
7KVC	Cryo-EM structure of Mal de Rio Cuarto virus P9-1 viroplasm protein (decamer) 分子名称: p9-1 著者 Llauger, G, Melero, R, Monti, D, Sycz, G, Huck-Iriart, C, Cerutti, M.L, Klinke, S, Arranz, R, Carazo, J.M, Goldbaum, F.A, del Vas, M, Otero, L.H. 登録日 2020-11-27 公開日 2022-06-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers. Mbio, 14, 2023
3DKF	Structure of MET receptor tyrosine kinase in complex with inhibitor SGX-523 分子名称: 6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline, CHLORIDE ION, Hepatocyte growth factor receptor 著者 Hendle, J. 登録日 2008-06-24 公開日 2009-07-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo. Mol.Cancer Ther., 8, 2009
8W26	X-ray crystal structure of the GAF-PHY domains of SyB-Cph1 分子名称: 1,2-ETHANEDIOL, ACETATE ION, PHYCOCYANOBILIN, ... 著者 Burgie, E.S, Vierstra, R.D. 登録日 2024-02-20 公開日 2024-05-22 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of the photosensory module from a PAS-less cyanobacterial phytochrome as Pr shows a mix of dark-adapted and photoactivated features. J.Biol.Chem., 300, 2024
7KTM	DNA Polymerase Mu (K438D), 8-oxodGTP:Ct Reaction State Ternary Complex, 50 mM Mn2+ (30min) 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.528 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KVD	Cryo-EM structure of Mal de Rio Cuarto virus P9-1 viroplasm protein (dodecamer) 分子名称: p9-1 著者 Llauger, G, Melero, R, Monti, D, Sycz, G, Huck-Iriart, C, Cerutti, M.L, Klinke, S, Arranz, R, Carazo, J.M, Goldbaum, F.A, del Vas, M, Otero, L.H. 登録日 2020-11-27 公開日 2022-06-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers. Mbio, 14, 2023
5LBS	structural basis of Zika and Dengue virus potent antibody cross-neutralization 分子名称: 1,2-ETHANEDIOL, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8, SULFATE ION, ... 著者 Vaney, M.C, Rouvinski, A, Barba-Spaeth, G, Rey, F.A. 登録日 2016-06-17 公開日 2016-07-06 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structural basis of potent Zika-dengue virus antibody cross-neutralization. Nature, 536, 2016
4Y34	Crystal Structure of Coxsackievirus B3 3D polymerase in complex with GPC-N143 分子名称: 2,2'-[(4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ... 著者 Vives-Adrian, L, Ferrer-Orta, C, Cerdaguer, N. 登録日 2015-02-10 公開日 2015-04-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11, 2015
8WA8	Human transketolase in complex with phosphite 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, PHOSPHITE ION, ... 著者 Liu, Z, Tittmann, K, Dai, S. 登録日 2023-09-07 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis Acs Catalysis, 14, 2024
8QDE	Crystal structure of a truncated human L-Lactate Dehydrogenase B protein in complex with NADH and oxamate 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, L-lactate dehydrogenase B chain, ... 著者 Van Gysel, M, Wouters, J. 登録日 2023-08-29 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Crystal structure of a truncated human L-Lactate Dehydrogenase B protein in complex with NADH and oxamate To Be Published
7L8V	NMR Structure of half-calcified calmodulin mutant (CaMEF12) bound to the IQ-motif of CaV1.2 分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Ames, J.B. 登録日 2021-01-01 公開日 2022-07-06 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Half-calcified calmodulin promotes basal activity and inactivation of the L-type calcium channel Ca V 1.2. J.Biol.Chem., 298, 2022
6G54	Crystal structure of ERK2 covalently bound to SM1-71 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Mitogen-activated protein kinase 1, ... 著者 Chaikuad, A, Suman, R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gray, N.S, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2018-03-29 公開日 2019-02-27 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome. Cell Chem Biol, 26, 2019
8B6D	Crystal structure of UDP-glucose pyrophosphorylase from Thermocrispum agreste DSM 44070 in complex with UDP 分子名称: 1,2-ETHANEDIOL, GLYCEROL, SODIUM ION, ... 著者 Laustsen, J, Kumpf, A, Bento, I. 登録日 2022-09-27 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure determination of a highly active UDP-glucose pyrophosphorylase from Thermocrispum agreste DSM 44070 To Be Published
4Y0V	Structure of an ADP ribosylation factor from Entamoeba histolytica HM-1:IMSS bound to Mg-GDP 分子名称: ADP-ribosylation factor 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2015-02-06 公開日 2015-03-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of an ADP-ribosylation factor, ARF1, from Entamoeba histolytica bound to Mg(2+)-GDP. Acta Crystallogr.,Sect.F, 71, 2015
6GES	Crystal structure of ERK1 covalently bound to SM1-71 分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 3, N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide, ... 著者 Chaikuad, A, Suman, R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gray, N.S, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2018-04-27 公開日 2019-02-27 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome. Cell Chem Biol, 26, 2019
3DD0	Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 分子名称: 6-ethoxy-1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R. 登録日 2008-06-04 公開日 2009-03-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties Biochemistry, 48, 2009
8BP0	Crystal structure of BHMeHis1.8, an engineered enzyme for the Morita-Baylis-Hillman reaction 分子名称: 1,2-ETHANEDIOL, BHMeHis1.8, TRIETHYLENE GLYCOL 著者 Hardy, F.J. 登録日 2022-11-15 公開日 2024-02-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.621 Å) 主引用文献 A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme. Nat Commun, 15, 2024
9IWD	High Resolution Crystal Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from Saccharomyces cerevisiae Complexed with a Maleate Derivative 分子名称: GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase 3, ethyl 4-[(4-chlorophenyl)amino]-4-oxidanylidene-butanoate 著者 Cao, H, Zhang, X, Ren, Y, Wan, J. 登録日 2024-07-25 公開日 2025-08-06 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 High Resolution Crystal Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from Saccharomyces cerevisiae Complexed with a Maleate Derivative To Be Published
5EVI	Crystal Structure of Beta-Lactamase/D-Alanine Carboxypeptidase from Pseudomonas syringae 分子名称: 1,2-ETHANEDIOL, Beta-Lactamase/D-Alanine Carboxypeptidase, SULFATE ION 著者 Kim, Y, Hatzos-Skintges, C, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2015-11-19 公開日 2016-01-13 最終更新日 2025-04-02 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of Beta-Lactamase/D-Alanine Carboxypeptidase from Pseudomonas syringae To Be Published
3H8W	Structure of D132N T4 RNase H in the presence of divalent magnesium 分子名称: Ribonuclease H 著者 Tomanicek, S.J, Mueser, T.C. 登録日 2009-04-29 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Additional Order Appears in the Absence of Metals in a FEN-1 protein: Structural Analysis of Magnesium Binding to Bacteriophage T4 RNaseH TO BE PUBLISHED
2NQ1	Solution Structures of a DNA Dodecamer Duplex 分子名称: 5'-D(*CP*CP*TP*CP*AP*GP*GP*CP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*GP*CP*CP*TP*GP*AP*GP*G)-3' 著者 Bhattacharyya, D, Wu, Y, Chaney, S, Campbell, S. 登録日 2006-10-30 公開日 2007-06-12 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution Structures of a DNA Dodecamer Duplex with and without a Cisplatin 1,2-d(GG) Intrastrand Cross-Link: Comparison with the Same DNA Duplex Containing an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link Biochemistry, 46, 2007
4XJ5	Crystal structure of Vibrio cholerae DncV 3'-deoxy GTP bound form 分子名称: 1,2-ETHANEDIOL, 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, Cyclic AMP-GMP synthase, ... 著者 Kato, K, Ishii, R, Ishitani, R, Nureki, O. 登録日 2015-01-08 公開日 2015-04-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.552 Å) 主引用文献 Structural Basis for the Catalytic Mechanism of DncV, Bacterial Homolog of Cyclic GMP-AMP Synthase Structure, 23, 2015
7A55	Structure of DYRK1A in complex with compound 8 分子名称: 3-(1-methylpyrazol-4-yl)-1~{H}-pyrazole-5-carboxylic acid, Dual specificity tyrosine-phosphorylation-regulated kinase 1A 著者 Dokurno, P, Surgenor, A.E, Hubbard, R.E. 登録日 2020-08-20 公開日 2021-06-30 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B. J.Med.Chem., 64, 2021
8WR5	The Crystal Structure of Mms2 from Biortus 分子名称: 1,2-ETHANEDIOL, SULFATE ION, Ubiquitin-conjugating enzyme E2 variant 2 著者 Wang, F, Cheng, W, Yuan, Z, Lin, D, Guo, S. 登録日 2023-10-13 公開日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The Crystal Structure of Mms2 from Biortus. To Be Published
6X6I	Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor SGT543 分子名称: 4-(4-benzyl-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butan-1-one, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Punetha, A, Garneau-Tsodikova, S, Tsodikov, O.V. 登録日 2020-05-28 公開日 2021-06-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.904 Å) 主引用文献 Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from Mycobacterium tuberculosis to overcome kanamycin resistance Rsc Med Chem, 12, 2021

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