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6HFP
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Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.0
分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者Ramon-Maiques, S, Grande Garcia, A.
登録日2018-08-21
公開日2018-10-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.1982286 Å)
主引用文献Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HG3
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Hybrid dihydroorotase domain of human CAD with E. coli flexible loop, bound to dihydroorotate
分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者Ramon-Maiques, S, Del Cano-Ochoa, F.
登録日2018-08-22
公開日2018-10-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
8PM2
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Structure of the murine trace amine-associated receptor TAAR7f bound to N,N-dimethylcyclohexylamine (DMCH) in complex with mini-Gs trimeric G protein
分子名称: CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Gusach, A, Lee, Y, Edwards, P.C, Huang, F, Weyand, S.N, Tate, C.G.
登録日2023-06-28
公開日2023-08-09
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Molecular recognition of an aversive odorant by the murine trace amine-associated receptor TAAR7f.
Biorxiv, 2023
6GFH
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Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with neo-IP5 and ATP
分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Whitfield, H.L, Brearley, C.A, Hemmings, A.M.
登録日2018-04-30
公開日2018-09-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase.
J. Med. Chem., 61, 2018
6GP3
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Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, inactive form
分子名称: CALCIUM ION, Ribonucleoside-diphosphate reductase beta chain
著者Srinivas, V, Lebrette, H, Lundin, D, Kutin, Y, Sahlin, M, Lerche, M, Enrich, J, Branca, R.M.M, Cox, N, Sjoberg, B.M, Hogbom, M.
登録日2018-06-05
公開日2018-08-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens.
Nature, 563, 2018
8OU1
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Crystal structure of the SPOC domain of mouse SPOCD1
分子名称: CITRATE ANION, SPOC domain-containing protein 1
著者Heep, M, Cook, A.G, O'Carroll, D.
登録日2023-04-21
公開日2024-02-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line.
Mol.Cell, 84, 2024
8JAT
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BU of 8jat by Molmil
Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus neoformans
分子名称: 3-ketodihydrosphingosine reductase TSC10, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhao, P, Kuang, Z.
登録日2023-05-07
公開日2023-06-21
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus neoformans.
Biochem.Biophys.Res.Commun., 670, 2023
6ILG
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CRYSTAL STRUCTURE OF BAT MHC CLASS I PTAL-N*01:01 FOR 2.6 ANGSTROM
分子名称: Beta-2-microglobulin, HEV-1-P8L, MHC class I antigen
著者Qu, Z.H, Zhang, N.Z, Xia, C.
登録日2018-10-18
公開日2019-07-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and Peptidome of the Bat MHC Class I Molecule Reveal a Novel Mechanism Leading to High-Affinity Peptide Binding.
J Immunol., 202, 2019
6II7
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BU of 6ii7 by Molmil
Crystal structure of Plasmodium falciparum adenosine deaminase C27Q+L227I mutant co-complexed with Zn ion, hypoxanthine and inosine
分子名称: Adenosine deaminase, HYPOXANTHINE, INOSINE, ...
著者Chitnumsub, P, Jaruwat, A.
登録日2018-10-03
公開日2019-05-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Crystal structure of Plasmodium falciparum adenosine deaminase reveals a novel binding pocket for inosine.
Arch. Biochem. Biophys., 667, 2019
6VPV
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Trimeric Photosystem I from the High-Light Tolerant Cyanobacteria Cyanobacterium Aponinum
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Dobson, Z, Toporik, H, Vaughn, N, Lin, S, Williams, D, Fromme, P, Mazor, Y.
登録日2020-02-04
公開日2021-08-04
最終更新日2021-09-08
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献The structure of photosystem I from a high-light tolerant Cyanobacteria.
Elife, 10, 2021
8AF2
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BU of 8af2 by Molmil
Human Sterol Carrier Protein with unnatural amino acid 2,2'-bipyridine alanine incorporated at position 111
分子名称: COPPER (II) ION, Enoyl-CoA hydratase 2, FRAGMENT OF TRITON X-100, ...
著者Richardson, J.M, Klemencic, E, Jarvis, A.G.
登録日2022-07-15
公開日2023-08-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Using BpyAla to generate copper artificial metalloenzymes: a catalytic and structural study.
Catalysis Science And Technology, 14, 2024
8AF3
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Sterol carrier protein Artifical metalloenzyme incorporating Q111C mutation coupled to 2,2'-bipyridine
分子名称: COPPER (II) ION, Enoyl-CoA hydratase 2, FRAGMENT OF TRITON X-100, ...
著者Richardson, J.M, Klemencic, E, Jarvis, A.G.
登録日2022-07-15
公開日2023-08-16
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Using BpyAla to generate copper artificial metalloenzymes: a catalytic and structural study.
Catalysis Science And Technology, 14, 2024
8BQE
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BU of 8bqe by Molmil
In situ structure of the Caulobacter crescentus S-layer
分子名称: 4-acetamido-4,6-dideoxy-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-3)-4-acetamido-4,6-dideoxy-alpha-D-mannopyranose-(1-3)-4-acetamido-4,6-dideoxy-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-3)-4-acetamido-4,6-dideoxy-alpha-D-mannopyranose, CALCIUM ION, S-layer protein rsaA
著者von Kuegelgen, A, Bharat, T.
登録日2022-11-21
公開日2022-12-28
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0.
Elife, 11, 2022
8BSH
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BU of 8bsh by Molmil
COPII inner coat
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein transport protein SEC23, ...
著者Zanetti, G, Pyle, E.W.
登録日2022-11-25
公開日2023-01-18
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0.
Elife, 11, 2022
8BP0
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BU of 8bp0 by Molmil
Crystal structure of BHMeHis1.8, an engineered enzyme for the Morita-Baylis-Hillman reaction
分子名称: 1,2-ETHANEDIOL, BHMeHis1.8, TRIETHYLENE GLYCOL
著者Hardy, F.J.
登録日2022-11-15
公開日2024-02-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.621 Å)
主引用文献A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme.
Nat Commun, 15, 2024
8BP1
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Crystal structure of BHMeHis1.0, an engineered enzyme for the Morita-Baylis-Hillman reaction
分子名称: ACETATE ION, BHMeHis1.0, DI(HYDROXYETHYL)ETHER, ...
著者Hardy, F.J.
登録日2022-11-15
公開日2024-02-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme.
Nat Commun, 15, 2024
4TNJ
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BU of 4tnj by Molmil
RT XFEL structure of Photosystem II 500 ms after the 2nd illumination (2F) at 4.5 A resolution
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Kern, J, Tran, R, Alonso-Mori, R, Koroidov, S, Echols, N, Hattne, J, Ibrahim, M, Gul, S, Laksmono, H, Sierra, R.G, Gildea, R.J, Han, G, Hellmich, J, Lassalle-Kaiser, B, Chatterjee, R, Brewster, A, Stan, C.A, Gloeckner, C, Lampe, A, DiFiore, D, Milathianaki, D, Fry, A.R, Seibert, M.M, Koglin, J.E, Gallo, E, Uhlig, J, Sokaras, D, Weng, T.-C, Zwart, P.H, Skinner, D.E, Bogan, M.J, Messerschmidt, M, Glatzel, P, Williams, G.J, Boutet, S, Adams, P.D, Zouni, A, Messinger, J, Sauter, N.K, Bergmann, U, Yano, J, Yachandra, V.K.
登録日2014-06-04
公開日2014-07-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Taking snapshots of photosynthetic water oxidation using femtosecond X-ray diffraction and spectroscopy.
Nat Commun, 5, 2014
4TNI
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BU of 4tni by Molmil
RT XFEL structure of Photosystem II 500 ms after the third illumination at 4.6 A resolution
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Kern, J, Tran, R, Alonso-Mori, R, Koroidov, S, Echols, N, Hattne, J, Ibrahim, M, Gul, S, Laksmono, H, Sierra, R.G, Gildea, R.J, Han, G, Hellmich, J, Lassalle-Kaiser, B, Chatterjee, R, Brewster, A, Stan, C.A, Gloeckner, C, Lampe, A, DiFiore, D, Milathianaki, D, Fry, A.R, Seibert, M.M, Koglin, J.E, Gallo, E, Uhlig, J, Sokaras, D, Weng, T.-C, Zwart, P.H, Skinner, D.E, Bogan, M.J, Messerschmidt, M, Glatzel, P, Williams, G.J, Boutet, S, Adams, P.D, Zouni, A, Messinger, J, Sauter, N.K, Bergmann, U, Yano, J, Yachandra, V.K.
登録日2014-06-04
公開日2014-07-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献Taking snapshots of photosynthetic water oxidation using femtosecond X-ray diffraction and spectroscopy.
Nat Commun, 5, 2014
4TNK
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RT XFEL structure of Photosystem II 250 microsec after the third illumination at 5.2 A resolution
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Kern, J, Tran, R, Alonso-Mori, R, Koroidov, S, Echols, N, Hattne, J, Ibrahim, M, Gul, S, Laksmono, H, Sierra, R.G, Gildea, R.J, Han, G, Hellmich, J, Lassalle-Kaiser, B, Chatterjee, R, Brewster, A, Stan, C.A, Gloeckner, C, Lampe, A, DiFiore, D, Milathianaki, D, Fry, A.R, Seibert, M.M, Koglin, J.E, Gallo, E, Uhlig, J, Sokaras, D, Weng, T.-C, Zwart, P.H, Skinner, D.E, Bogan, M.J, Messerschmidt, M, Glatzel, P, Williams, G.J, Boutet, S, Adams, P.D, Zouni, A, Messinger, J, Sauter, N.K, Bergmann, U, Yano, J, Yachandra, V.K.
登録日2014-06-04
公開日2014-07-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (5.2 Å)
主引用文献Taking snapshots of photosynthetic water oxidation using femtosecond X-ray diffraction and spectroscopy.
Nat Commun, 5, 2014
4TNH
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BU of 4tnh by Molmil
RT XFEL structure of Photosystem II in the dark state at 4.9 A resolution
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Kern, J, Tran, R, Alonso-Mori, R, Koroidov, S, Echols, N, Hattne, J, Ibrahim, M, Gul, S, Laksmono, H, Sierra, R.G, Gildea, R.J, Han, G, Hellmich, J, Lassalle-Kaiser, B, Chatterjee, R, Brewster, A, Stan, C.A, Gloeckner, C, Lampe, A, DiFiore, D, Milathianaki, D, Fry, A.R, Seibert, M.M, Koglin, J.E, Gallo, E, Uhlig, J, Sokaras, D, Weng, T.-C, Zwart, P.H, Skinner, D.E, Bogan, M.J, Messerschmidt, M, Glatzel, P, Williams, G.J, Boutet, S, Adams, P.D, Zouni, A, Messinger, J, Sauter, N.K, Bergmann, U, Yano, J, Yachandra, V.K.
登録日2014-06-04
公開日2014-07-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.900007 Å)
主引用文献Taking snapshots of photosynthetic water oxidation using femtosecond X-ray diffraction and spectroscopy.
Nat Commun, 5, 2014
5SBG
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BU of 5sbg by Molmil
The crystal structure of METP in complex with Zn at a resolution of 1.34 A.
分子名称: METP, miniaturized rubredoxin, ZINC ION
著者Di Costanzo, L, La Gatta, S, Chino, M.
登録日2021-08-24
公開日2023-02-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.338 Å)
主引用文献Designed Rubredoxin miniature in a fully artificial electron chain triggered by visible light
Nat Commun, 14, 2023
5SBI
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BU of 5sbi by Molmil
The crystal structure of METP in complex with Co at a resolution of 1.80A.
分子名称: COBALT (II) ION, METP, miniaturized rubredoxin
著者Di Costanzo, L, La Gatta, S, Leone, L, Chino, M.
登録日2021-08-24
公開日2023-02-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Miniaturization process reloaded - structural and functional insights from a miniaturized rubredoxin
To be published
5SBJ
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The crystal structure of METP in complex with Cd at a resolution of 1.29 A.
分子名称: CADMIUM ION, METP, miniaturized rubredoxin
著者Di Costanzo, L, La Gatta, S, Pavone, V.
登録日2021-08-24
公開日2023-02-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Miniaturization process reloaded - structural and functional insights from a miniaturized rubredoxin
To be published
5T93
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BU of 5t93 by Molmil
Immunoglobulin light chain variable domain AL-T05
分子名称: ACETATE ION, ALT-05 immunoglobulin light chain variable domain from light chain amyloidosis patient, ZINC ION
著者Ramirez-Alvarado, M, Blancas-Mejia, L.M.
登録日2016-09-09
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Differences in Protein Concentration Dependence for Nucleation and Elongation in Light Chain Amyloid Formation.
Biochemistry, 56, 2017
5T35
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The PROTAC MZ1 in complex with the second bromodomain of Brd4 and pVHL:ElonginC:ElonginB
分子名称: (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Bromodomain-containing protein 4, Transcription elongation factor B polypeptide 1, ...
著者Gadd, M.S, Zengerle, M, Ciulli, A.
登録日2016-08-24
公開日2017-03-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of PROTAC cooperative recognition for selective protein degradation.
Nat. Chem. Biol., 13, 2017

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