6II7
Crystal structure of Plasmodium falciparum adenosine deaminase C27Q+L227I mutant co-complexed with Zn ion, hypoxanthine and inosine
Summary for 6II7
| Entry DOI | 10.2210/pdb6ii7/pdb |
| Descriptor | Adenosine deaminase, INOSINE, HYPOXANTHINE, ... (5 entities in total) |
| Functional Keywords | tim barrel, hydrolase |
| Biological source | Plasmodium falciparum 3D7 (isolate 3D7) |
| Total number of polymer chains | 1 |
| Total formula weight | 43084.00 |
| Authors | Chitnumsub, P.,Jaruwat, A. (deposition date: 2018-10-03, release date: 2019-05-01, Last modification date: 2023-11-22) |
| Primary citation | Jaruwat, A.,Riangrungroj, P.,Ubonprasert, S.,Sae-Ueng, U.,Kuaprasert, B.,Yuthavong, Y.,Leartsakulpanich, U.,Chitnumsub, P. Crystal structure of Plasmodium falciparum adenosine deaminase reveals a novel binding pocket for inosine. Arch. Biochem. Biophys., 667:6-13, 2019 Cited by PubMed: 31002765DOI: 10.1016/j.abb.2019.04.002 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.48 Å) |
Structure validation
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