6II7
Crystal structure of Plasmodium falciparum adenosine deaminase C27Q+L227I mutant co-complexed with Zn ion, hypoxanthine and inosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Adenosine deaminase | polymer | 367 | 42548.8 | 1 | UniProt (Q8IJA9) Pfam (PF00962) | Plasmodium falciparum 3D7 (isolate 3D7) | |
| 2 | B (A) | INOSINE | non-polymer | 268.2 | 1 | Chemie (NOS) | |||
| 3 | C (A) | HYPOXANTHINE | non-polymer | 136.1 | 1 | Chemie (HPA) | |||
| 4 | D, E (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | F (A) | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A: 1 - 367 (UniProt: Q8IJA9)
| PDB | External Database | Details |
|---|---|---|
| Gln 27 | Cys 27 | engineered mutation |
| Ile 227 | Leu 227 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42548.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 535.2 | |
| All* | Total formula weight | 43084.0 |
