6II7
Crystal structure of Plasmodium falciparum adenosine deaminase C27Q+L227I mutant co-complexed with Zn ion, hypoxanthine and inosine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Adenosine deaminase | polymer | 367 | 42548.8 | 1 | UniProt (Q8IJA9) Pfam (PF00962) In PDB | Plasmodium falciparum 3D7 (isolate 3D7) | |
2 | A | INOSINE | non-polymer | 268.2 | 1 | Chemie (NOS) | |||
3 | A | HYPOXANTHINE | non-polymer | 136.1 | 1 | Chemie (HPA) | |||
4 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
5 | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A: 1 - 367 (UniProt: Q8IJA9)
PDB | External Database | Details |
---|---|---|
Gln 27 | Cys 27 | engineered mutation |
Ile 227 | Leu 227 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42548.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 535.2 | |
All* | Total formula weight | 43084.0 |