4K8P
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![BU of 4k8p by Molmil](/molmil-images/mine/4k8p) | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 2-ethylbenzyl alcohol | 分子名称: | (2-ETHYLPHENYL)METHANOL, ADENOSINE, DIMETHYL SULFOXIDE, ... | 著者 | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-04-18 | 公開日 | 2013-05-01 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 2-ethylbenzyl alcohol To be Published
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1I1D
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![BU of 1i1d by Molmil](/molmil-images/mine/1i1d) | CRYSTAL STRUCTURE OF YEAST GNA1 BOUND TO COA AND GLNAC-6P | 分子名称: | 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, COENZYME A, GLUCOSAMINE-PHOSPHATE N-ACETYLTRANSFERASE, ... | 著者 | Peneff, C, Mengin-Lecreulx, D, Bourne, Y. | 登録日 | 2001-02-01 | 公開日 | 2001-05-16 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structures of Apo and complexed Saccharomyces cerevisiae GNA1 shed light on the catalytic mechanism of an amino-sugar N-acetyltransferase. J.Biol.Chem., 276, 2001
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1WDK
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![BU of 1wdk by Molmil](/molmil-images/mine/1wdk) | fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native2) | 分子名称: | 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, ... | 著者 | Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K. | 登録日 | 2004-05-17 | 公開日 | 2004-07-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex Embo J., 23, 2004
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4GA3
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![BU of 4ga3 by Molmil](/molmil-images/mine/4ga3) | Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with BPH-1260 | 分子名称: | 1-butyl-3-(2-hydroxy-2,2-diphosphonoethyl)-1H-imidazol-3-ium, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... | 著者 | Liu, Y.-L, Zhang, Y, Oldfield, E. | 登録日 | 2012-07-24 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Chemo-Immunotherapeutic Anti-Malarials Targeting Isoprenoid Biosynthesis. ACS MED.CHEM.LETT., 4, 2013
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4KAY
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1S7K
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3ID0
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![BU of 3id0 by Molmil](/molmil-images/mine/3id0) | Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with 3-Fluoro-1-(2-hydroxy-2,2-bisphosphono-ethyl)pyridinium | 分子名称: | 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... | 著者 | Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E. | 登録日 | 2009-07-19 | 公開日 | 2010-02-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer. Proteins, 78, 2010
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1I5B
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![BU of 1i5b by Molmil](/molmil-images/mine/1i5b) | STRUCTURE OF CHEA DOMAIN P4 IN COMPLEX WITH ADPNP AND MANGANESE | 分子名称: | ACETATE ION, CHEMOTAXIS PROTEIN CHEA, MANGANESE (II) ION, ... | 著者 | Bilwes, A.M, Quezada, C.M, Croal, L.R, Crane, B.R, Simon, M.I. | 登録日 | 2001-02-26 | 公開日 | 2001-08-26 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Nucleotide binding by the histidine kinase CheA. Nat.Struct.Biol., 8, 2001
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4KFA
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![BU of 4kfa by Molmil](/molmil-images/mine/4kfa) | Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate | 分子名称: | 1,2-ETHANEDIOL, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... | 著者 | Barnett, B.L, Tsoumpra, M.K, Muniz, J.R.C, Walter, R.L. | 登録日 | 2013-04-26 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate To be Published
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6A2N
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![BU of 6a2n by Molmil](/molmil-images/mine/6a2n) | Crystal structure of quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum DHFR-TS complexed with BT2, NADPH, and dUMP | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-6-ethylpyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | 著者 | Chitnumsub, P, Jaruwat, A, Tarnchampoo, B, Yuthavong, Y. | 登録日 | 2018-06-12 | 公開日 | 2019-04-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance. ACS Med Chem Lett, 9, 2018
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1I5C
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![BU of 1i5c by Molmil](/molmil-images/mine/1i5c) | STRUCTURE OF CHEA DOMAIN P4 IN COMPLEX WITH ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHEMOTAXIS PROTEIN CHEA | 著者 | Bilwes, A.M, Quezada, C.M, Croal, L.R, Crane, B.R, Simon, M.I. | 登録日 | 2001-02-26 | 公開日 | 2001-08-26 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nucleotide binding by the histidine kinase CheA. Nat.Struct.Biol., 8, 2001
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1X07
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![BU of 1x07 by Molmil](/molmil-images/mine/1x07) | Crystal structure of undecaprenyl pyrophosphate synthase in complex with Mg and IPP | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Guo, R.-T, Ko, T.-P, Chen, A.P.-C, Kuo, C.-J, Wang, A.H.-J, Liang, P.-H. | 登録日 | 2005-03-15 | 公開日 | 2005-03-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis. J.Biol.Chem., 280, 2005
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1M4I
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![BU of 1m4i by Molmil](/molmil-images/mine/1m4i) | Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis-Complex with Coenzyme A and Kanamycin A | 分子名称: | 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, Aminoglycoside 2'-N-acetyltransferase, COENZYME A, ... | 著者 | Vetting, M.W, Hegde, S.S, Javid-Majd, F, Blanchard, J.S, Roderick, S.L. | 登録日 | 2002-07-02 | 公開日 | 2002-08-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis in complex with coenzyme A and aminoglycoside substrates. Nat.Struct.Biol., 9, 2002
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4K9I
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![BU of 4k9i by Molmil](/molmil-images/mine/4k9i) | CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with Norharmane | 分子名称: | ADENOSINE, DIMETHYL SULFOXIDE, Norharmane, ... | 著者 | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-04-19 | 公開日 | 2013-05-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with Norharmane To be Published
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1N08
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![BU of 1n08 by Molmil](/molmil-images/mine/1n08) | Crystal Structure of Schizosaccharomyces pombe Riboflavin Kinase Reveals a Novel ATP and Riboflavin Binding Fold | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ZINC ION, putative riboflavin kinase | 著者 | Bauer, S, Kemter, K, Bacher, A, Huber, R, Fischer, M, Steinbacher, S. | 登録日 | 2002-10-11 | 公開日 | 2003-02-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure of Schizosaccharomyces pombe Riboflavin Kinase Reveals a Novel ATP and Riboflavin Binding Fold J.Mol.Biol., 326, 2003
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3I8P
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1SEJ
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2ZCS
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![BU of 2zcs by Molmil](/molmil-images/mine/2zcs) | Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-700 | 分子名称: | Dehydrosqualene synthase, tripotassium (1R)-4-biphenyl-4-yl-1-phosphonatobutane-1-sulfonate | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H, Oldfield, E. | 登録日 | 2007-11-11 | 公開日 | 2008-03-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science, 319, 2008
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3IQG
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![BU of 3iqg by Molmil](/molmil-images/mine/3iqg) | |
1J3I
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![BU of 1j3i by Molmil](/molmil-images/mine/1j3i) | Wild-type Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with WR99210, NADPH, and dUMP | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | 著者 | Yuvaniyama, J, Chitnumsub, P, Kamchonwongpaisan, S, Vanichtanankul, J, Sirawaraporn, W, Taylor, P, Walkinshaw, M, Yuthavong, Y. | 登録日 | 2003-02-03 | 公開日 | 2003-05-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Insights into antifolate resistance from malarial DHFR-TS structures. NAT.STRUCT.BIOL., 10, 2003
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1S7N
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![BU of 1s7n by Molmil](/molmil-images/mine/1s7n) | Ribosomal L7/L12 alpha-N-protein acetyltransferase in complex with Coenzyme A (CoA free sulfhydryl) | 分子名称: | COENZYME A, acetyl transferase | 著者 | Vetting, M.W, de Carvalho, L.P, Roderick, S.L, Blanchard, J.S. | 登録日 | 2004-01-29 | 公開日 | 2005-03-15 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A novel dimeric structure of the RimL Nalpha-acetyltransferase from Salmonella typhimurium. J.Biol.Chem., 280, 2005
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1WDM
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![BU of 1wdm by Molmil](/molmil-images/mine/1wdm) | fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native3) | 分子名称: | 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, Fatty oxidation complex alpha subunit, ... | 著者 | Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K. | 登録日 | 2004-05-17 | 公開日 | 2004-07-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex Embo J., 23, 2004
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2RBK
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4KOU
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![BU of 4kou by Molmil](/molmil-images/mine/4kou) | Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefixime | 分子名称: | (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 1,2-ETHANEDIOL, SULFATE ION, ... | 著者 | Majorek, K.A, Chruszcz, M, Otwinowski, Z, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2013-05-12 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794: A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA. J.Biol.Chem., 288, 2013
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2R98
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![BU of 2r98 by Molmil](/molmil-images/mine/2r98) | Crystal Structure of N-acetylglutamate synthase (selenoMet substituted) from Neisseria gonorrhoeae | 分子名称: | ACETYL COENZYME *A, Putative acetylglutamate synthase | 著者 | Shi, D, Sagar, V, Jin, Z, Yu, X, Caldovic, L, Morizono, H, Allewell, N.M, Tuchman, M. | 登録日 | 2007-09-12 | 公開日 | 2008-01-15 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The crystal structure of N-acetyl-L-glutamate synthase from Neisseria gonorrhoeae provides insights into mechanisms of catalysis and regulation. J.Biol.Chem., 283, 2008
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