PDB: 7755 件ウェブページステータス検索Chemie searchBIRD

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4ND4	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (pyruvic acid) and cofactor (b-nicotinamide adenine dinucleotide) 分子名称: GLYCEROL, Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
4ND3	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (l-lactic acid) and cofactor (b-nicotinamide adenine dinucleotide) 分子名称: (2S)-2-HYDROXYPROPANOIC ACID, GLYCEROL, Lactate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
4NEO	Structure of BlmI, a type-II acyl-carrier-protein from Streptomyces verticillus involved in bleomycin biosynthesis 分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, Peptide synthetase NRPS type II-PCP 著者 Cuff, M.E, Bigelow, L, Bearden, J, Babnigg, G, Bruno, C.J.P, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) 登録日 2013-10-29 公開日 2014-01-29 最終更新日 2023-03-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins. Proteins, 82, 2014
8BQU	Molecular basis of ZP3/ZP1 heteropolymerization: crystal structure of a native vertebrate egg coat filament 分子名称: Choriogenin H, Zona pellucida sperm-binding protein 3, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Bokhove, M, de Sanctis, D, Yasumasu, S, Jovine, L. 登録日 2022-11-21 公開日 2024-03-13 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat. Cell, 187, 2024
3NKF	Crystal structure of human ligand-free mature caspase-6 with intersubunit linker attached 分子名称: Caspase-6 著者 Vaidya, S, Hardy, J.A. 登録日 2010-06-18 公開日 2010-12-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Substrate-Induced Conformational Changes Occur in All Cleaved Forms of Caspase-6. J.Mol.Biol., 406, 2011
1VIT	THROMBIN:HIRUDIN 51-65 COMPLEX 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA THROMBIN, ... 著者 Vitali, J, Edwards, B.F.P. 登録日 1996-01-31 公開日 1997-04-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure of a bovine thrombin-hirudin51-65 complex determined by a combination of molecular replacement and graphics. Incorporation of known structural information in molecular replacement. Acta Crystallogr.,Sect.D, 52, 1996
1UWB	TYR 181 CYS HIV-1 RT/8-CL TIBO 分子名称: 5-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE, REVERSE TRANSCRIPTASE 著者 Das, K, Ding, J, Hsiou, Y, Arnold, E. 登録日 1996-11-21 公開日 1997-05-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant. J.Mol.Biol., 264, 1996
2HD0	Structure of the catalytic domain of hepatitis C virus NS2 分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, Protease NS2-3 (p23), octyl beta-D-glucopyranoside 著者 Lorenz, I.C, Rice, C.M, Marcotrigiano, J. 登録日 2006-06-19 公開日 2006-08-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structure of the catalytic domain of the hepatitis C virus NS2-3 protease. Nature, 442, 2006
4DRQ	Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52: Complex of FKBP51 with 2-(3-((R)-1-((S)-1-(3,5-dichlorophenylsulfonyl)piperidine-2-carbonyloxy)-3-(3,4-dimethoxy -phenyl)propyl)phenoxy)acetic acid 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, {3-[(1S)-1-[({(2S)-1-[(3,5-dichlorophenyl)sulfonyl]piperidin-2-yl}carbonyl)oxy]-3-(3,4-dimethoxyphenyl)propyl]phenoxy}acetic acid 著者 Gopalakrishnan, R, Kozany, C, Wang, Y, Hoogeland, B, Bracher, A, Hausch, F, Schneider, S. 登録日 2012-02-17 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52. J.Med.Chem., 55, 2012
4ND1	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with cofactor (b-nicotinamide adenine dinucleotide) and inhibitor (oxamic acid) 分子名称: GLYCEROL, Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
4ND2	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (pyruvic acid) and cofactor analog (3-acetylpyridine adenine dinucleotide) 分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, GLYCEROL, Lactate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
8BH3	DNA-PK Ku80 mediated dimer bound to PAXX 分子名称: DNA (25-MER), DNA (26-MER), DNA (27-MER), ... 著者 Hardwick, S.W, Chaplin, A.K. 登録日 2022-10-28 公開日 2023-06-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.55 Å) 主引用文献 PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
8BHV	DNA-PK XLF mediated dimer bound to PAXX 分子名称: DNA (24-MER), DNA (26-MER), DNA (27-MER), ... 著者 Hardwick, S.W, Chaplin, A.K. 登録日 2022-11-01 公開日 2023-06-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.51 Å) 主引用文献 PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
8BHY	DNA-PK Ku80 mediated dimer bound to PAXX and XLF 分子名称: DNA (25-MER), DNA (26-MER), DNA (27-MER), ... 著者 Hardwick, S.W, Chaplin, A.K. 登録日 2022-11-01 公開日 2023-06-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (5.33 Å) 主引用文献 PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
4M52	Structure of Mtb Lpd bound to SL827 分子名称: Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, N~2~-[(2-amino-5-bromopyridin-3-yl)sulfonyl]-N-(4-methoxyphenyl)-N~2~-methylglycinamide 著者 Lima, C.D. 登録日 2013-08-07 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase. Biochemistry, 52, 2013
1TBR	CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN 分子名称: RHODNIIN, THROMBIN 著者 Van De Locht, A, Lamba, D, Bode, W. 登録日 1995-03-03 公開日 1996-10-14 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin. EMBO J., 14, 1995
1TBQ	CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN 分子名称: RHODNIIN, THROMBIN 著者 Van De Locht, A, Lamba, D, Bode, W. 登録日 1995-03-02 公開日 1996-10-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin. EMBO J., 14, 1995
8SEM	Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni 分子名称: TRPV1 inhibitory peptide Tst2 著者 Elnahriry, K.A, Wai, D.C.C, Norton, R.S. 登録日 2023-04-10 公開日 2023-09-27 実験手法 SOLUTION NMR 主引用文献 Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni. Biochim Biophys Acta Proteins Proteom, 1872, 2023
2HRV	2A CYSTEINE PROTEINASE FROM HUMAN RHINOVIRUS 2 分子名称: 2A CYSTEINE PROTEINASE, ZINC ION 著者 Petersen, J.F.W, Cherney, M.M, Liebig, H.-D, Skern, T, Kuechler, E, James, M.N.G. 登録日 1999-04-29 公開日 2000-05-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis. EMBO J., 18, 1999
8SED	Structure of a new ShKT peptide from the sea anemone Telmatactis stephensoni: ShKT-Ts1 分子名称: ShKT peptide ShKT-Ts1 著者 Sanches, K, Siedoks, A.A, Wai, D.C.C, Norton, R.S. 登録日 2023-04-09 公開日 2023-10-18 最終更新日 2024-01-17 実験手法 SOLUTION NMR 主引用文献 Structure-function relationships in ShKT domain peptides: ShKT-Ts1 from the sea anemone Telmatactis stephensoni. Proteins, 92, 2024
4EY0	Structure of tandem SH2 domains from PLCgamma1 分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 著者 Cole, A.R, Mas-Droux, C.P, Bunney, T.D, Katan, M. 登録日 2012-05-01 公開日 2012-10-31 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and Functional Integration of the PLCgamma Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation. Structure, 20, 2012
8CD8	Ulilysin - C269A with AEBSF complex 分子名称: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, CALCIUM ION, GLY-SER-SER, ... 著者 Rodriguez-Banqueri, A, Eckhard, U, Gomis-Ruth, F.X. 登録日 2023-01-30 公開日 2023-03-22 最終更新日 2023-03-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural insights into latency of the metallopeptidase ulilysin (lysargiNase) and its unexpected inhibition by a sulfonyl-fluoride inhibitor of serine peptidases. Dalton Trans, 52, 2023
8C18	Solution structure of carotenoid-binding protein AstaPo1 in complex with astaxanthin 分子名称: ASTAXANTHIN, Astaxanthin binding fasciclin family protein 著者 Kornilov, F.D, Savitskaya, A.G, Slonimskiy, Y.B, Goncharuk, S.A, Sluchanko, N.N, Mineev, K.S. 登録日 2022-12-20 公開日 2023-04-05 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Structural basis for the ligand promiscuity of the neofunctionalized, carotenoid-binding fasciclin domain protein AstaP. Commun Biol, 6, 2023
8P5R	Crystal structure of full-length, homohexameric 2-oxoglutarate dehydrogenase KGD from Mycobacterium smegmatis in complex with GarA 分子名称: CALCIUM ION, Glycogen accumulation regulator GarA, MAGNESIUM ION, ... 著者 Wagner, T, Mechaly, A.M, Alzari, P.M, Bellinzoni, M. 登録日 2023-05-24 公開日 2023-08-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (4.562 Å) 主引用文献 High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase. Nat Commun, 14, 2023
8OTM	structure of InhA from mycobacterium tuberculosis in complex with N-((1-(3-hydroxy-4-phenoxybenzyl)-1H-1,2,3-triazol-4-yl)methyl)-2-oxo-2H-chromene-3-carboxamide 分子名称: 1,2-ETHANEDIOL, 2-oxidanylidene-~{N}-[[1-[(3-oxidanyl-4-phenoxy-phenyl)methyl]-1,2,3-triazol-4-yl]methyl]chromene-3-carboxamide, ACETATE ION, ... 著者 Chebaiki, M, Maveyraud, L, Tamhaev, R, Lherbet, C, Mourey, L. 登録日 2023-04-21 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA. Eur.J.Med.Chem., 259, 2023

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