6F5E
| Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_10_47 in complex JNK1a1 and JIP1 peptide | 分子名称: | C-Jun-amino-terminal kinase-interacting protein 1, DD_D12_10_47, Mitogen-activated protein kinase 8 | 著者 | Wu, Y, Mittl, P.R, Honegger, A, Batyuk, A, Plueckthun, A. | 登録日 | 2017-12-01 | 公開日 | 2017-12-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_10_47 in complex JNK1a1 and JIP1 peptide To be published
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2H96
| Discovery of Potent, Highly Selective, and Orally Bioavailable Pyridine Carboxamide C-jun NH2-terminal Kinase Inhibitors | 分子名称: | 5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE, C-jun-amino-terminal kinase-interacting protein 1, GLYCEROL, ... | 著者 | Abad-Zapatero, C. | 登録日 | 2006-06-09 | 公開日 | 2006-07-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Discovery of potent, highly selective, and orally bioavailable pyridine carboxamide c-Jun NH2-terminal kinase inhibitors. J.Med.Chem., 49, 2006
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7QH6
| Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 1 | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L13, mitochondrial, ... | 著者 | Rebelo-Guiomar, P, Pellegrino, S, Dent, K.C, Warren, A.J, Minczuk, M. | 登録日 | 2021-12-10 | 公開日 | 2022-03-02 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit. Nat Commun, 13, 2022
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4UZU
| Three-dimensional structure of a variant `Termamyl-like' Geobacillus stearothermophilus alpha-amylase at 1.9 A resolution | 分子名称: | ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION, ... | 著者 | Offen, W.A, Anderson, C, Borchert, T.V, Wilson, K.S, Davies, G.J. | 登録日 | 2014-09-09 | 公開日 | 2015-01-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Three-Dimensional Structure of a Variant `Termamyl-Like' Geobacillus Stearothermophilus Alpha-Amylase at 1.9 A Resolution Acta Crystallogr.,Sect.F, 71, 2015
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4V7L
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7PO4
| Assembly intermediate of human mitochondrial ribosome large subunit (largely unfolded rRNA with MALSU1, L0R8F8 and ACP) | 分子名称: | 16SrRNA, 39S ribosomal protein L10, mitochondrial, ... | 著者 | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | 登録日 | 2021-09-08 | 公開日 | 2022-06-15 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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6FUZ
| Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of JIP1 | 分子名称: | GLYCEROL, Kinesin light chain 1,Kinesin light chain 1,C-Jun-amino-terminal kinase-interacting protein 1, nanobody | 著者 | Pernigo, S, Dodding, M.P, Steiner, R.A. | 登録日 | 2018-02-28 | 公開日 | 2018-05-02 | 最終更新日 | 2019-09-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors. Elife, 7, 2018
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6GFJ
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6PW9
| Cryo-EM structure of human NatE/HYPK complex | 分子名称: | ACETYL COENZYME *A, Huntingtin-interacting protein K, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Deng, S, Marmorstein, R. | 登録日 | 2019-07-22 | 公開日 | 2020-02-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | 主引用文献 | Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK. Nat Commun, 11, 2020
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5HTO
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5HRU
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5HS4
| Plasmdoium Vivax Lactate dehydrogenase | 分子名称: | L-lactate dehydrogenase | 著者 | Choi, S.J, Ban, C. | 登録日 | 2016-01-25 | 公開日 | 2016-10-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.339 Å) | 主引用文献 | Crystal structure of a DNA aptamer bound to PvLDH elucidates novel single-stranded DNA structural elements for folding and recognition Sci Rep, 6, 2016
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3CLJ
| Structure of the RNA polymerase II CTD-interacting domain of Nrd1 | 分子名称: | GLYCEROL, Protein NRD1, SULFATE ION | 著者 | Vasiljeva, L, Kim, M, Mutschler, H, Buratowski, S, Meinhart, A. | 登録日 | 2008-03-19 | 公開日 | 2008-07-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Nrd1-Nab3-Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain. Nat.Struct.Mol.Biol., 15, 2008
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6LNM
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1A22
| HUMAN GROWTH HORMONE BOUND TO SINGLE RECEPTOR | 分子名称: | GROWTH HORMONE, GROWTH HORMONE RECEPTOR | 著者 | De Vos, A.M, Ultsch, M. | 登録日 | 1998-01-15 | 公開日 | 1998-04-29 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. J.Mol.Biol., 277, 1998
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3E1R
| Midbody targeting of the ESCRT machinery by a non-canonical coiled-coil in CEP55 | 分子名称: | Centrosomal protein of 55 kDa, Programmed cell death 6-interacting protein | 著者 | Lee, H.H, Elia, N, Ghirlando, R, Lippincott-Schwartz, J, Hurley, J.H. | 登録日 | 2008-08-04 | 公開日 | 2008-11-04 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55. Science, 322, 2008
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2ZL1
| MP1-p14 Scaffolding complex | 分子名称: | Mitogen-activated protein kinase kinase 1-interacting protein 1, Mitogen-activated protein-binding protein-interacting protein | 著者 | Schrag, J.D, Cygler, M, Munger, C, Magloire, A. | 登録日 | 2008-04-02 | 公開日 | 2008-06-24 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular dynamics-solvated interaction energy studies of protein-protein interactions: the MP1-p14 scaffolding complex. J.Mol.Biol., 379, 2008
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3C3Q
| ALIX Bro1-domain:CHMIP4B co-crystal structure | 分子名称: | Charged multivesicular body protein 4b peptide, GLYCEROL, Programmed cell death 6-interacting protein | 著者 | McCullough, J.B, Fisher, R.D, Whitby, F.G, Sundquist, W.I, Hill, C.P. | 登録日 | 2008-01-28 | 公開日 | 2008-06-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | ALIX-CHMP4 interactions in the human ESCRT pathway. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3C3R
| ALIX BRO1 CHMP4C complex | 分子名称: | Charged multivesicular body protein 4c peptide, GLYCEROL, Programmed cell death 6-interacting protein | 著者 | McCullough, J.B, Fisher, R.D, Whitby, F.G, Sundquist, W.I, Hill, C.P. | 登録日 | 2008-01-28 | 公開日 | 2008-06-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | ALIX-CHMP4 interactions in the human ESCRT pathway. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3C3O
| ALIX Bro1-domain:CHMIP4A co-crystal structure | 分子名称: | Charged multivesicular body protein 4a peptide, GLYCEROL, Programmed cell death 6-interacting protein | 著者 | McCullough, J.B, Fisher, R.D, Whitby, F.G, Sundquist, W.I, Hill, C.P. | 登録日 | 2008-01-28 | 公開日 | 2008-06-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | ALIX-CHMP4 interactions in the human ESCRT pathway. Proc.Natl.Acad.Sci.Usa, 105, 2008
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7ABI
| Human pre-Bact-2 spliceosome | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ... | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | 登録日 | 2020-09-07 | 公開日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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5LA4
| Crystal structure of apo human proheparanase | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Heparanase, ... | 著者 | Wu, L, Jin, Y, Davies, G.J. | 登録日 | 2016-06-13 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Activity-based probes for functional interrogation of retaining beta-glucuronidases. Nat. Chem. Biol., 13, 2017
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2KA1
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6TP5
| Crystal structure of human Transmembrane prolyl 4-hydroxylase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Myllykoski, M, Sutinen, A, Koski, M.K, Kallio, J.P, Raasakka, A, Myllyharju, J, Wierenga, R.K, Koivunen, P. | 登録日 | 2019-12-12 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains. J.Biol.Chem., 296, 2020
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5L9Z
| Crystal structure of human heparanase nucleophile mutant (E343Q), in complex with unreacted glucuronic acid configured aziridine probe JJB355 | 分子名称: | (1~{R},2~{S},3~{R},4~{S},5~{S},6~{R})-7-[8-[(azanylidene-{4}-azanylidene)amino]octyl]-3,4,5-tris(oxidanyl)-7-azabicyclo[4.1.0]heptane-2-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wu, L, Jin, Y, Davies, G.J. | 登録日 | 2016-06-13 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Activity-based probes for functional interrogation of retaining beta-glucuronidases. Nat. Chem. Biol., 13, 2017
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