3C3Q

ALIX Bro1-domain:CHMIP4B co-crystal structure

Summary for 3C3Q

Entry DOI	10.2210/pdb3c3q/pdb
Related	2oew 3C3O 3C3R
Descriptor	Programmed cell death 6-interacting protein, Charged multivesicular body protein 4b peptide, GLYCEROL, ... (4 entities in total)
Functional Keywords	alix chmp4b bro1 amphipathic-helix, cataract, disease mutation, protein transport, transport, apoptosis, host-virus interaction, transport protein
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm, cytosol: Q8WUM4 Q9H444
Total number of polymer chains	2
Total formula weight	44986.16
Authors	McCullough, J.B.,Fisher, R.D.,Whitby, F.G.,Sundquist, W.I.,Hill, C.P. (deposition date: 2008-01-28, release date: 2008-06-10, Last modification date: 2024-02-21)
Primary citation	McCullough, J.,Fisher, R.D.,Whitby, F.G.,Sundquist, W.I.,Hill, C.P. ALIX-CHMP4 interactions in the human ESCRT pathway. Proc.Natl.Acad.Sci.Usa, 105:7687-7691, 2008 Cited by PubMed: 18511562 DOI: 10.1073/pnas.0801567105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation