6ZJG
 
 | | Crystal structure of ACPA E4 in complex with CII-C-48-CIT | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACPA E4 Fab fragment - heavy chain, ACPA E4 Fab fragment - light chain, ... | | 著者 | Ge, C, Holmdahl, R. | | 登録日 | 2020-06-29 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal structure of ACPA E4 in complex with CII-C-48-CIT
To Be Published
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1CMX
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8F8N
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8QC9
 | | Crystal structure of the outer membrane decaheme cytochrome MtrC (A293Boc-Lys) | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | | 著者 | Nash, B.W, Lockwood, C.J, Edwards, M.J, Whiting, K, Butt, J.N, Clarke, T.A. | | 登録日 | 2023-08-25 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Genetic Code Expansion in Shewanella oneidensis MR-1 Allows Site-Specific Incorporation of Bioorthogonal Functional Groups into a c -Type Cytochrome.
Acs Synth Biol, 13, 2024
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8QBQ
 | | Crystal structure of the outer membrane decaheme cytochrome MtrC (A430Boc-Lys) | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | | 著者 | Nash, B.W, Lockwood, C.J, Whiting, K, Butt, J.N, Clarke, T.A, Edwards, M.J. | | 登録日 | 2023-08-25 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Genetic Code Expansion in Shewanella oneidensis MR-1 Allows Site-Specific Incorporation of Bioorthogonal Functional Groups into a c -Type Cytochrome.
Acs Synth Biol, 13, 2024
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8QBZ
 | | Crystal structure of the outer membrane decaheme cytochrome MtrC (E344Boc-Lys) | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | | 著者 | Edwards, M.J, Lockwood, C.J, Whiting, K, Nash, B.W, Butt, J.N, Clarke, T.A. | | 登録日 | 2023-08-25 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Genetic Code Expansion in Shewanella oneidensis MR-1 Allows Site-Specific Incorporation of Bioorthogonal Functional Groups into a c -Type Cytochrome.
Acs Synth Biol, 13, 2024
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7ANQ
 | | Complete PCSK9 C-ter domain in complex with VHH P1.40 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Proprotein convertase subtilisin/kexin type 9, SULFATE ION, ... | | 著者 | Ciccone, L, Legrand, P, Stura, E.A, Dive, V, Seidahn, N.G, Fruchart Gaillard, C. | | 登録日 | 2020-10-12 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels.
Mol Metab, 67, 2022
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1CHH
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6NZT
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1CHJ
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1CTY
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1CTZ
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1CHI
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1DII
 | | CRYSTAL STRUCTURE OF P-CRESOL METHYLHYDROXYLASE AT 2.5 A RESOLUTION | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, HEME C, ... | | 著者 | Cunane, L.M, Chen, Z.W, Shamala, N, Mathews, F.S, Cronin, C.N, McIntire, W.S. | | 登録日 | 1999-11-29 | | 公開日 | 1999-12-08 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of the flavocytochrome p-cresol methylhydroxylase and its enzyme-substrate complex: gated substrate entry and proton relays support the proposed catalytic mechanism.
J.Mol.Biol., 295, 2000
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8DK6
 | | Structure of hepatitis C virus envelope N-terminal truncated glycoprotein 2 (E2) (residues 456-713) from J6 genotype | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2A12 Fab Heavy chain, 2A12 Fab light chain, ... | | 著者 | Kumar, A, Rohe, T, Elrod, E.J, Khan, A.G, Dearborn, A.D, Kissinger, R, Grakoui, A, Marcotrigiano, J. | | 登録日 | 2022-07-03 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Regions of hepatitis C virus E2 required for membrane association.
Nat Commun, 14, 2023
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6SPT
 | | High resolution crystal structure of N-terminal domain of PEX14 from Trypanosoma brucei in complex with the fist compound with sub-micromolar trypanocidal activity | | 分子名称: | 5-[(4-methoxynaphthalen-1-yl)methyl]-1-[2-[(2-methyl-1-oxidanyl-propan-2-yl)amino]ethyl]-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | | 著者 | Napolitano, V, Dawidowski, M, Kalel, V.C, Fino, R, Emmanouilidis, L, Lenhart, D, Ostertag, M, Kaiser, M, Kolonko, M, Schilebs, W, Maser, P, Tetko, I, Hadian, K, Plettenburg, O, Erdmann, R, Sattler, M, Popowicz, G.M, Dubin, G. | | 登録日 | 2019-09-02 | | 公開日 | 2020-01-01 | | 最終更新日 | 2020-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure-Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity.
J.Med.Chem., 63, 2020
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7VBT
 | | Crystal structure of RIOK2 in complex with CQ211 | | 分子名称: | 8-(6-methoxypyridin-3-yl)-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]-5H-[1,2,3]triazolo[4,5-c]quinolin-4-one, Serine/threonine-protein kinase RIO2 | | 著者 | Zhu, C, Zhang, Z.M. | | 登録日 | 2021-09-01 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.54001474 Å) | | 主引用文献 | Discovery of 8-(6-Methoxypyridin-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1,5-dihydro- 4H -[1,2,3]triazolo[4,5- c ]quinolin-4-one (CQ211) as a Highly Potent and Selective RIOK2 Inhibitor.
J.Med.Chem., 65, 2022
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7VU7
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8VJ1
 | | Structure of C-terminal domain of telomere resolvase, ResT, from Borrelia garinii | | 分子名称: | Telomere resolvase ResT | | 著者 | Semper, C, Savchenko, A, Watanabe, N, Center for Structural Biology of Infectious Diseases (CSBID) | | 登録日 | 2024-01-05 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structure analysis of the telomere resolvase from the Lyme disease spirochete Borrelia garinii reveals functional divergence of its C-terminal domain.
Nucleic Acids Res., 52, 2024
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1CIF
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6NZV
 | | Crystal structure of HCV NS3/4A protease in complex with compound 12 | | 分子名称: | (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide, HCV NS3/4A protease, SULFATE ION, ... | | 著者 | Appleby, T.C, Taylor, J.G. | | 登録日 | 2019-02-14 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®.
Bioorg.Med.Chem.Lett., 29, 2019
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1CIG
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1CRH
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1CIE
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1CGO
 | | CYTOCHROME C' | | 分子名称: | CYTOCHROME C, HEME C | | 著者 | Dobbs, A.J, Faber, H.R, Anderson, B.F, Baker, E.N. | | 登録日 | 1995-05-01 | | 公開日 | 1995-07-31 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Three-dimensional structure of cytochrome c' from two Alcaligenes species and the implications for four-helix bundle structures.
Acta Crystallogr.,Sect.D, 52, 1996
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