8C1C
 
 | | Structure of IgE bound to the ectodomain of FceRIa | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, ... | | 著者 | Andersen, G.R, Jensen, R.K. | | 登録日 | 2022-12-20 | | 公開日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structure of IgE bound to the ectodomain of FceRIa
To Be Published
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8C1B
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8JBV
 | | Extracellular domain of gamma delta TCR | | 分子名称: | T cell receptor delta variable 1,T cell receptor delta constant, T cell receptor gamma variable 5,T cell receptor gamma constant 1 | | 著者 | Xin, W, Chi, X, Huang, B, Su, Q, Zhou, Q. | | 登録日 | 2023-05-09 | | 公開日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 2024
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3BKJ
 | | Crystal structure of Fab wo2 bound to the n terminal domain of amyloid beta peptide (1-16) | | 分子名称: | Amyloid Beta Peptide, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | | 著者 | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | | 登録日 | 2007-12-06 | | 公開日 | 2008-04-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
J.Mol.Biol., 377, 2008
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1MCH
 | | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | | 分子名称: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-B-ALA-B-ALA-OH | | 著者 | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | | 登録日 | 1993-02-25 | | 公開日 | 1994-01-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Principles and pitfalls in designing site-directed peptide ligands.
Proteins, 16, 1993
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1M7I
 | | CRYSTAL STRUCTURE OF A MONOCLONAL FAB SPECIFIC FOR SHIGELLA FLEXNERI Y LIPOPOLYSACCHARIDE COMPLEXED WITH A PENTASACCHARIDE | | 分子名称: | alpha-L-rhamnopyranose-(1-2)-alpha-L-rhamnopyranose-(1-3)-alpha-L-rhamnopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-methyl 6-deoxy-alpha-L-rhamnopyranoside, heavy chain of the monoclonal antibody Fab SYA/J6, light chain of the monoclonal antibody Fab SYA/J6 | | 著者 | Vyas, N.K, Vyas, M.N, Chervenak, M.C, Johnson, M.A, Pinto, B.M, Bundle, D.R, Quiocho, F.A. | | 登録日 | 2002-07-19 | | 公開日 | 2003-07-22 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for
Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodynamics
Biochemistry, 41, 2002
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1MCB
 | | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | | 分子名称: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-OH | | 著者 | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | | 登録日 | 1993-02-25 | | 公開日 | 1994-01-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Principles and pitfalls in designing site-directed peptide ligands.
Proteins, 16, 1993
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1MPA
 | | BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS | | 分子名称: | CADMIUM ION, MN12H2 IGG2A-KAPPA, PORA P1.16 PEPTIDE FLUORESCEIN CONJUGATE | | 著者 | Van Den Elsen, J.M.H, Herron, J.N, Kroon, J, Gros, P. | | 登録日 | 1997-02-26 | | 公開日 | 1997-09-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide.
Proteins, 29, 1997
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3BKM
 | | Structure of anti-amyloid-beta Fab WO2 (Form A, P212121) | | 分子名称: | SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa, ... | | 著者 | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | | 登録日 | 2007-12-07 | | 公開日 | 2008-04-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
J.Mol.Biol., 377, 2008
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3CFJ
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7B0B
 | | Fab HbnC3t1p1_C6 bound to SARS-CoV-2 RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, IGK@ protein, ... | | 著者 | Borenstein-Katz, A, Diskin, R. | | 登録日 | 2020-11-19 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants.
Immunity, 56, 2023
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4MX7
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6XNG
 | | MHC-like protein complex structure | | 分子名称: | (3R)-N-[(2S,3R)-1-(alpha-D-galactopyranosyloxy)-3-hydroxyheptadecan-2-yl]-3-hydroxyheptadecanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Thirunavukkarasu, P, Le Nours, J, Rossjohn, J. | | 登録日 | 2020-07-02 | | 公開日 | 2021-11-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Host immunomodulatory lipids created by symbionts from dietary amino acids.
Nature, 600, 2021
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4NDM
 | | Structure of the AB18.1 TCR | | 分子名称: | Human nkt tcr alpha chain, T-cell gamma protein,T-cell receptor beta-2 chain C region | | 著者 | Luoma, A.M, Adams, E.J. | | 登録日 | 2013-10-27 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.0065 Å) | | 主引用文献 | Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells.
Immunity, 39, 2013
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4NJ9
 | | Crystal structure of Fab 8B10 in complex with MPTS | | 分子名称: | 8-methoxypyrene-1,3,6-trisulfonic acid, 8B10 heavy chain, 8B10 light chain, ... | | 著者 | Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A. | | 登録日 | 2013-11-08 | | 公開日 | 2014-11-12 | | 最終更新日 | 2017-06-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
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4NPY
 | | Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody | | 分子名称: | GLYCEROL, germline PGT121 heavy chain, germline PGT121 light chain | | 著者 | Julien, J.-P, Diwanji, D.C, Wilson, I.A. | | 登録日 | 2013-11-22 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | | 主引用文献 | The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies.
Plos Pathog., 9, 2013
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6YJP
 | | Crystal structure of a complex between glycosylated NKp30 and its deglycosylated tumour ligand B7-H6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Natural cytotoxicity triggering receptor 3, Natural cytotoxicity triggering receptor 3 ligand 1 | | 著者 | Skalova, T, Dohnalek, J, Skorepa, O, Kalouskova, B, Pazicky, S, Blaha, J, Vanek, O. | | 登録日 | 2020-04-04 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its N -Glycosylation.
Cancers (Basel), 12, 2020
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4NJA
 | | Crystal structure of Fab 6C8 in complex with MPTS | | 分子名称: | 6C8 heavy chain, 6C8 light chain, 8-methoxypyrene-1,3,6-trisulfonic acid, ... | | 著者 | Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A. | | 登録日 | 2013-11-08 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | | 主引用文献 | Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
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5XRQ
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6E4Z
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6E9I
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6E4Y
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6EAQ
 | | Glycosylated FCGR3B / CD16b in complex with afucosylated IgG1 Fc | | 分子名称: | Immunoglobulin gamma-1 heavy chain, Low affinity immunoglobulin gamma Fc region receptor III-B, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Roberts, J.T, Barb, A.W. | | 登録日 | 2018-08-03 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | A single amino acid distorts the Fc gamma receptor IIIb/CD16b structure upon binding immunoglobulin G1 and reduces affinity relative to CD16a.
J. Biol. Chem., 293, 2018
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6E9G
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6E9H
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