PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

---

6ZJ5	Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcDMJ and hexatungstotellurate(VI) TEW 分子名称: 1-DEOXYMANNOJIRIMYCIN, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-tungstotellurate(VI), ... 著者 Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. 登録日 2020-06-27 公開日 2020-12-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.269 Å) 主引用文献 Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
1OT7	Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR 分子名称: 6-ETHYL-CHENODEOXYCHOLIC ACID, Bile Acid Receptor, ISO-URSODEOXYCHOLIC ACID, ... 著者 Mi, L.Z, Devarakonda, S, Harp, J.M, Han, Q, Pellicciari, R, Willson, T.M, Khorasanizadeh, S, Rastinejad, F. 登録日 2003-03-21 公開日 2004-03-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR Mol.Cell, 11, 2003
5XYF	Crystal structure of the human TIN2-TPP1-TRF2 telomeric complex 分子名称: Adrenocortical dysplasia protein homolog, TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2 著者 Hu, C, Chen, Y. 登録日 2017-07-07 公開日 2017-12-13 実験手法 X-RAY DIFFRACTION (2.202 Å) 主引用文献 Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex. Cell Res., 27, 2017
4XE9	Crystal structure of the NanB sialidase from Streptococcus pneumoniae in complex with Optactin 分子名称: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B 著者 Brear, P. 登録日 2014-12-23 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XJW	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with DMSO as the cryoprotectant 分子名称: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Brear, P. 登録日 2015-01-09 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XOG	CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH Optactin and DANA 分子名称: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, DIMETHYL SULFOXIDE, ... 著者 Brear, P. 登録日 2015-01-16 公開日 2016-02-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XJ9	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 5.0 in 50mM Sodium Acetate with DMSO as the cryoprotectant 分子名称: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B 著者 Brear, P. 登録日 2015-01-08 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XHX	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin and 2-[(3-Chlorobenzyl)ammonio]ethanesulfonate 分子名称: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, 2-[(3-chlorobenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, ... 著者 Brear, P. 登録日 2015-01-06 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
5T0N	Pseudo-apo structure of Sestrin2 at 3.0 angstrom resolution 分子名称: LEUCINE, Sestrin-2 著者 Saxton, R.A, Knockenhauer, K.E, Schwartz, T.U. 登録日 2016-08-16 公開日 2016-10-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.004 Å) 主引用文献 The apo-structure of the leucine sensor Sestrin2 is still elusive. Sci.Signal., 9, 2016
4XIL	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with MPD as the cryoprotectant 分子名称: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, Sialidase B 著者 Brear, P. 登録日 2015-01-07 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XMA	Crystal structure of the K499G mutant of NanB sialidase from streptococcus pneumoniae in complex with Optactin 分子名称: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B 著者 Brear, P. 登録日 2015-01-14 公開日 2016-02-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
5FMU	MmIFT54 CH-domain 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, TRAF3-INTERACTING PROTEIN 1 著者 Weber, K, Lorentzen, E. 登録日 2015-11-09 公開日 2016-03-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.593 Å) 主引用文献 Intraflagellar Transport Proteins 172, 80, 57, 54, 38, and 20 Form a Stable Tubulin-Binding Ift-B2 Complex. Embo J., 35, 2016
6PW9	Cryo-EM structure of human NatE/HYPK complex 分子名称: ACETYL COENZYME *A, Huntingtin-interacting protein K, INOSITOL HEXAKISPHOSPHATE, ... 著者 Deng, S, Marmorstein, R. 登録日 2019-07-22 公開日 2020-02-19 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (4.03 Å) 主引用文献 Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK. Nat Commun, 11, 2020
2KA2	Solution NMR structure of BNIP3 transmembrane peptide dimer in detergent micelles with His173-Ser172 intermonomer hydrogen bond restraints 分子名称: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 著者 Sulistijo, E.S, MacKenzie, K.R. 登録日 2008-10-30 公開日 2009-06-23 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural basis for dimerization of the BNIP3 transmembrane domain Biochemistry, 48, 2009
2KA1	Solution NMR structure of BNIP3 transmembrane peptide dimer in detergent micelles 分子名称: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 著者 Sulistijo, E.S, MacKenzie, K.R. 登録日 2008-10-30 公開日 2009-06-23 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Structural basis for dimerization of the BNIP3 transmembrane domain Biochemistry, 48, 2009
7ABI	Human pre-Bact-2 spliceosome 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-07 公開日 2021-02-10 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
6EJN	The KLC2 TPR domain bound to the JIP3 leucine zipper domain 分子名称: C-Jun-amino-terminal kinase-interacting protein 3, Kinesin light chain 2 著者 Cockburn, J, Hesketh, S.J, Way, M. 登録日 2017-09-22 公開日 2018-09-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Insights into Kinesin-1 Activation from the Crystal Structure of KLC2 Bound to JIP3. Structure, 26, 2018
6F5E	Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_10_47 in complex JNK1a1 and JIP1 peptide 分子名称: C-Jun-amino-terminal kinase-interacting protein 1, DD_D12_10_47, Mitogen-activated protein kinase 8 著者 Wu, Y, Mittl, P.R, Honegger, A, Batyuk, A, Plueckthun, A. 登録日 2017-12-01 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_10_47 in complex JNK1a1 and JIP1 peptide To be published
7ABG	Human pre-Bact-1 spliceosome 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-07 公開日 2020-12-23 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (7.8 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
6FUZ	Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of JIP1 分子名称: GLYCEROL, Kinesin light chain 1,Kinesin light chain 1,C-Jun-amino-terminal kinase-interacting protein 1, nanobody 著者 Pernigo, S, Dodding, M.P, Steiner, R.A. 登録日 2018-02-28 公開日 2018-05-02 最終更新日 2019-09-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors. Elife, 7, 2018
3V3V	Structural and functional analysis of quercetagetin, a natural JNK1 inhibitor 分子名称: 3,5,6,7-TETRAHYDROXY-2-(3,4-DIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, C-Jun-amino-terminal kinase-interacting protein 1, CHLORIDE ION, ... 著者 Baek, S, Kang, N.J, Popowicz, G.M, Arciniega, M, Jung, S.K, Byun, S, Song, N.R, Heo, Y.S, Kim, B.Y, Lee, H.J, Holak, T.A, Augustin, M, Bode, A.M, Huber, R, Dong, Z, Lee, K.W. 登録日 2011-12-14 公開日 2012-12-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and Functional Analysis of the Natural JNK1 Inhibitor Quercetagetin. J.Mol.Biol., 425, 2013
6GFJ	Structure of RIP2 CARD domain fused to crystallisable MBP tag 分子名称: Sugar ABC transporter substrate-binding protein,Receptor-interacting serine/threonine-protein kinase 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Pellegrini, E, Cusack, S. 登録日 2018-04-30 公開日 2019-03-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling. Nat Commun, 9, 2018
5RJX	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z285782452 分子名称: N-methyl-2-(methylsulfonyl)aniline, PH-interacting protein 著者 Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. 登録日 2020-06-02 公開日 2020-06-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.291 Å) 主引用文献 PanDDA analysis group deposition of ground-state model To Be Published
5RKD	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z2168282707 分子名称: (6S)-1-methyl-4,5,6,7-tetrahydro-1H-benzotriazole-6-carboxylic acid, PH-interacting protein 著者 Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. 登録日 2020-06-02 公開日 2020-06-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.237 Å) 主引用文献 PanDDA analysis group deposition of ground-state model To Be Published
5RJJ	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with NCL-00023833 分子名称: 4-bromanyl-1,8-naphthyridine, PH-interacting protein 著者 Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. 登録日 2020-06-02 公開日 2020-06-17 実験手法 X-RAY DIFFRACTION (1.151 Å) 主引用文献 PanDDA analysis group deposition of ground-state model To Be Published

<182183184185186187188189190191192193194195196197>