5XYF

Crystal structure of the human TIN2-TPP1-TRF2 telomeric complex

Summary for 5XYF

• Entry DOI: 10.2210/pdb5xyf/pdb
• Descriptor: TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2, Adrenocortical dysplasia protein homolog, ... (4 entities in total)
• Functional Keywords: telomere, shelterin complex, protein binding
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus . Isoform 1: Nucleus matrix : Q9BSI4; Nucleus : Q15554 Q96AP0
• Total number of polymer chains: 3
• Total formula weight: 29833.56

Authors

Hu, C.,Chen, Y. (deposition date: 2017-07-07, release date: 2017-12-13)

• Primary citation: Hu, C.,Rai, R.,Huang, C.,Broton, C.,Long, J.,Xu, Y.,Xue, J.,Lei, M.,Chang, S.,Chen, Y.; Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex.; Cell Res., 27:1485-1502, 2017; PubMed: 29160297; DOI: 10.1038/cr.2017.144

Experimental method

X-RAY DIFFRACTION (2.202 Å)