5XYF
Crystal structure of the human TIN2-TPP1-TRF2 telomeric complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TERF1-interacting nuclear factor 2 | polymer | 204 | 23180.2 | 1 | UniProt (Q9BSI4) Pfam (PF14973) | Homo sapiens (Human) | TRF1-interacting nuclear protein 2 |
| 2 | B (C) | Telomeric repeat-binding factor 2 | polymer | 18 | 2146.6 | 1 | UniProt (Q15554) | Homo sapiens (Human) | TTAGGG repeat-binding factor 2,Telomeric DNA-binding protein |
| 3 | C (B) | Adrenocortical dysplasia protein homolog | polymer | 40 | 4506.8 | 1 | UniProt (Q96AP0) | Homo sapiens (Human) | POT1 and TIN2-interacting protein |
| 4 | D, E, F (A, C, B) | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A: 2 - 202 (UniProt: Q9BSI4)
C: 350 - 366 (UniProt: Q15554)
B: 510 - 544 (UniProt: Q96AP0)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 349 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 505 | - | expression tag |
| Asp 506 | - | expression tag |
| Pro 507 | - | expression tag |
| Arg 508 | - | expression tag |
| Ser 509 | - | expression tag |
| Ala 518 | Val 518 | see sequence details |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 29833.6 | |
| All* | Total formula weight | 29833.6 |
