7U2X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u2x by Molmil](/molmil-images/mine/7u2x) | Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the down conformation | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Shyng, S.L, Sung, M.W, Driggers, C.M. | 登録日 | 2022-02-25 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
|
|
7U2K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u2k by Molmil](/molmil-images/mine/7u2k) | C6-guano bound Mu Opioid Receptor-Gi Protein Complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Wang, H, Kobilka, B. | 登録日 | 2022-02-24 | 公開日 | 2022-12-07 | 最終更新日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure-based design of bitopic ligands for the μ-opioid receptor. Nature, 613, 2023
|
|
7U2V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u2v by Molmil](/molmil-images/mine/7u2v) | |
7Z18
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z18 by Molmil](/molmil-images/mine/7z18) | E. coli C-P lyase bound to a PhnK ABC dimer and ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, ... | 著者 | Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. | 登録日 | 2022-02-24 | 公開日 | 2022-05-25 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (1.98 Å) | 主引用文献 | Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase. Nat Commun, 14, 2023
|
|
7Z19
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z19 by Molmil](/molmil-images/mine/7z19) | E. coli C-P lyase bound to a single PhnK ABC domain | 分子名称: | Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ... | 著者 | Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. | 登録日 | 2022-02-24 | 公開日 | 2022-05-25 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase. Nat Commun, 14, 2023
|
|
7Z17
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z17 by Molmil](/molmil-images/mine/7z17) | E. coli C-P lyase bound to a PhnK ABC dimer in an open conformation | 分子名称: | Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ... | 著者 | Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. | 登録日 | 2022-02-24 | 公開日 | 2022-05-25 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase. Nat Commun, 14, 2023
|
|
7Z15
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z15 by Molmil](/molmil-images/mine/7z15) | E. coli C-P lyase bound to a PhnK/PhnL dual ABC dimer and ADP + Pi | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, ... | 著者 | Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. | 登録日 | 2022-02-24 | 公開日 | 2022-06-22 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (1.93 Å) | 主引用文献 | Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase. Nat Commun, 14, 2023
|
|
7Z16
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z16 by Molmil](/molmil-images/mine/7z16) | E. coli C-P lyase bound to PhnK/PhnL dual ABC dimer with AMPPNP and PhnK E171Q mutation | 分子名称: | Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI, ... | 著者 | Amstrup, S.K, Sofus, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. | 登録日 | 2022-02-24 | 公開日 | 2022-06-22 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.09 Å) | 主引用文献 | Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase. Nat Commun, 14, 2023
|
|
7Z0Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z0z by Molmil](/molmil-images/mine/7z0z) | Abortive infection DNA polymerase AbiK from Lactococcus lactis, Y44F variant | 分子名称: | AbiK | 著者 | Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M. | 登録日 | 2022-02-24 | 公開日 | 2022-09-07 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases. Nucleic Acids Res., 50, 2022
|
|
7Z1G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z1g by Molmil](/molmil-images/mine/7z1g) | Crystal structure of nonphosphorylated (Tyr216) GSK3b in complex with CX-4945 | 分子名称: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Glycogen synthase kinase-3 beta, IMIDAZOLE, ... | 著者 | Grygier, P, Pustelny, K, Dubin, G, Czarna, A. | 登録日 | 2022-02-24 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal structure of nonphosphorylated (Tyr216) GSK3b kinase in complex with CX-4945 To Be Published
|
|
7Z1F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z1f by Molmil](/molmil-images/mine/7z1f) | Crystal structure of GSK3b in complex with CX-4945 | 分子名称: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Glycogen synthase kinase-3 beta, IMIDAZOLE, ... | 著者 | Grygier, P, Pustelny, K, Dubin, G, Czarna, A. | 登録日 | 2022-02-24 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of phosphorylated (Tyr216) GSK3b kinase in complex with CX-4945 To Be Published
|
|
7U2Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u2q by Molmil](/molmil-images/mine/7u2q) | |
7U2T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u2t by Molmil](/molmil-images/mine/7u2t) | |
7Z11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z11 by Molmil](/molmil-images/mine/7z11) | Structure of substrate bound DRG1 (AFG2) | 分子名称: | ATPase family gene 2 protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, peptide substrate | 著者 | Prattes, M, Grishkovskaya, I, Bergler, H, Haselbach, D. | 登録日 | 2022-02-24 | 公開日 | 2022-09-21 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1. Nat.Struct.Mol.Biol., 29, 2022
|
|
7U2P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u2p by Molmil](/molmil-images/mine/7u2p) | Structure of TcdA GTD in complex with RhoA | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Glucosyltransferase TcdA, MAGNESIUM ION, ... | 著者 | Baohua, C, Zheng, L, Kay, P, Rongsheng, J. | 登録日 | 2022-02-24 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.596 Å) | 主引用文献 | Structure of the glucosyltransferase domain of TcdA in complex with RhoA provides insights into substrate recognition. Sci Rep, 12, 2022
|
|
7U2L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u2l by Molmil](/molmil-images/mine/7u2l) | C5guano-uOR-Gi-scFv16 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Wang, H, Qu, Q, Skiniotis, G, Kobilka, B. | 登録日 | 2022-02-24 | 公開日 | 2022-05-04 | 最終更新日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure-based design of bitopic ligands for the μ-opioid receptor. Nature, 613, 2023
|
|
7X1U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x1u by Molmil](/molmil-images/mine/7x1u) | Structure of Thyrotropin-Releasing Hormone Receptor bound with an Endogenous Peptide Agonist TRH. | 分子名称: | Endogenous Peptide Agonist TRH, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yang, F, Zhang, H.H, Meng, X.Y, Li, Y.G, Zhou, Y.X, Ling, S.L, Liu, L, Shi, P, Tian, C.L. | 登録日 | 2022-02-24 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue. Cell Res., 32, 2022
|
|
7X1T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x1t by Molmil](/molmil-images/mine/7x1t) | Structure of Thyrotropin-Releasing Hormone Receptor bound with Taltirelin. | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ScFv16, ... | 著者 | Yang, F, Zhang, H.H, Meng, X.Y, Li, Y.G, Zhou, Y.X, Ling, S.L, Liu, L, Shi, P, Tian, C.L. | 登録日 | 2022-02-24 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue. Cell Res., 32, 2022
|
|
7X1L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x1l by Molmil](/molmil-images/mine/7x1l) | Malate dehydrogenase from Geobacillus stearothermophilus (gs-MDH) delta E311 mutant complexed with Nicotinamide Adenine Dinucleotide (NAD+) | 分子名称: | Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Shimozawa, Y, Himiyama, T, Nakamura, T, Nishiya, Y. | 登録日 | 2022-02-24 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Reducing substrate inhibition of malate dehydrogenase from Geobacillus stearothermophilus by C-terminal truncation. Protein Eng.Des.Sel., 35, 2022
|
|
7X1W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x1w by Molmil](/molmil-images/mine/7x1w) | |
7Z0L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z0l by Molmil](/molmil-images/mine/7z0l) | IL-27 signalling complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... | 著者 | Jin, Y, Gardner, S, Bubeck, D. | 登録日 | 2022-02-23 | 公開日 | 2022-07-27 | 最終更新日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural insights into the assembly and activation of the IL-27 signaling complex. Embo Rep., 23, 2022
|
|
7Z0T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z0t by Molmil](/molmil-images/mine/7z0t) | Structure of the Escherichia coli formate hydrogenlyase complex (aerobic preparation, composite structure) | 分子名称: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, CARBONMONOXIDE-(DICYANO) IRON, FE (III) ION, ... | 著者 | Steinhilper, R, Murphy, B.J. | 登録日 | 2022-02-23 | 公開日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli. Nat Commun, 13, 2022
|
|
7Z0S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z0s by Molmil](/molmil-images/mine/7z0s) | |
7U24
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u24 by Molmil](/molmil-images/mine/7u24) | Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and glibenclamide with Kir6.2-CTD in the up conformation | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ... | 著者 | Shyng, S.L, Sung, M.W, Driggers, C.M. | 登録日 | 2022-02-23 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
|
|
7X0Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x0q by Molmil](/molmil-images/mine/7x0q) | |