4L3B
 
 | | X-ray structure of the HRV2 A particle uncoating intermediate | | 分子名称: | Protein VP1, Protein VP2, Protein VP3 | | 著者 | Vives-Adrian, L, Querol-Audi, J, Garriga, D, Pous, J, Verdaguer, N. | | 登録日 | 2013-06-05 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (6.5 Å) | | 主引用文献 | Uncoating of common cold virus is preceded by RNA switching as determined by X-ray and cryo-EM analyses of the subviral A-particle.
Proc.Natl.Acad.Sci.USA, 110, 2013
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8PTG
 | | Structure of the transcription termination factor Rho bound to RNA at the PBS and SBS | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Said, N, Hilal, T, Wahl, M.C. | | 登録日 | 2023-07-14 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation.
Nat Commun, 15, 2024
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1R7Z
 | | NMR STRUCTURE OF THE R(GGAGGACAUUCCUCACGGGUGACCGUGGUCCUCC), DOMAIN IV STEM-LOOP B OF ENTEROVIRAL IRES WITH AUUCCU BULGE | | 分子名称: | 34-MER | | 著者 | Du, Z, Ulyanov, N.B, Yu, J, James, T.L. | | 登録日 | 2003-10-22 | | 公開日 | 2004-05-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structures of Loop B RNAs from the Stem-Loop IV Domain of the Enterovirus Internal Ribosome Entry Site: A Single C to U Substitution Drastically Changes the Shape and Flexibility of RNA(,).
Biochemistry, 43, 2004
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2MTF
 | | Solution structure of the La motif of human LARP6 | | 分子名称: | La-related protein 6 | | 著者 | Martino, L, Salisbury, N.JH, Atkinson, A.R, Kelly, G, Conte, M.R. | | 登録日 | 2014-08-18 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.
Nucleic Acids Res., 43, 2015
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8UMT
 | | Atomic model of the human CTF18-RFC-PCNA binary complex in the three-subunit binding state (state 2) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, MAGNESIUM ION, ... | | 著者 | Wang, F, He, Q, Li, H. | | 登録日 | 2023-10-18 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | | 主引用文献 | Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
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1R7W
 | | NMR STRUCTURE OF THE R(GGAGGACAUCCCUCACGGGUGACCGUGGUCCUCC), DOMAIN IV STEM-LOOP B OF ENTEROVIRAL IRES WITH AUCCCU BULGE | | 分子名称: | 34-MER | | 著者 | Du, Z, Ulyanov, N.B, Yu, J, James, T.L. | | 登録日 | 2003-10-22 | | 公開日 | 2004-05-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structures of Loop B RNAs from the Stem-Loop IV Domain of the Enterovirus Internal Ribosome Entry Site: A Single C to U Substitution Drastically Changes the Shape and Flexibility of RNA(,).
Biochemistry, 43, 2004
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4QM7
 | | Structure of bacterial polynucleotide kinase bound to GTP and pDNA | | 分子名称: | DNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Das, U, Wang, L.K, Smith, P, Shuman, S. | | 登録日 | 2014-06-15 | | 公開日 | 2014-10-08 | | 最終更新日 | 2015-02-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of bacterial polynucleotide kinase in a michaelis complex with nucleoside triphosphate (NTP)-Mg2+ and 5'-OH RNA and a mixed substrate-product complex with NTP-Mg2+ and a 5'-phosphorylated oligonucleotide.
J.Bacteriol., 196, 2014
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3KC6
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4H4K
 | | Structure of the Cmr2-Cmr3 subcomplex of the Cmr RNA-silencing complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cmr subunit Cmr2, CRISPR system Cmr subunit Cmr3, ... | | 著者 | Shao, Y, Cocozaki, A.I, Ramia, N.F, Terns, R.M, Terns, M.P, Li, H. | | 登録日 | 2012-09-17 | | 公開日 | 2013-03-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | | 主引用文献 | Structure of the cmr2-cmr3 subcomplex of the cmr RNA silencing complex.
Structure, 21, 2013
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2MTG
 | | Solution structure of the RRM1 of human LARP6 | | 分子名称: | La-related protein 6 | | 著者 | Martino, L, Atkinson, A.R, Kelly, G, Conte, M.R. | | 登録日 | 2014-08-18 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.
Nucleic Acids Res., 43, 2015
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7KL3
 | | The crystal structure of the 2009/H1N1/California PA endonuclease mutant E119D bound to RNA oligomer AG*CAUC (*uncleaveable bond, -UC disordered) | | 分子名称: | 5'-O-sulfocytidine, ADENOSINE MONOPHOSPHATE, GLYCEROL, ... | | 著者 | Cuypers, M.G, Kumar, G, White, S.W. | | 登録日 | 2020-10-28 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism.
Nucleic Acids Res., 49, 2021
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5UV5
 | | Crystal Structure of a 2-Hydroxyisoquinoline-1,3-dione RNase H Active Site Inhibitor with Multiple Binding Modes to HIV Reverse Transcriptase | | 分子名称: | 7-(furan-2-yl)-2-hydroxyisoquinoline-1,3(2H,4H)-dione, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H, ... | | 著者 | Kirby, K.A, Sarafianos, S.G. | | 登録日 | 2017-02-19 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A 2-Hydroxyisoquinoline-1,3-Dione Active-Site RNase H Inhibitor Binds in Multiple Modes to HIV-1 Reverse Transcriptase.
Antimicrob. Agents Chemother., 61, 2017
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4KFZ
 | | Crystal structure of LMO2 and anti-LMO2 VH complex | | 分子名称: | Anti-LMO2 VH, LMO-2, ZINC ION | | 著者 | Sewell, H, Tanaka, T, El Omari, K, Cruz-Migoni, A, Mancini, E.J, Fuentes-Fernandez, N, Chambers, J, Rabbitts, T.H. | | 登録日 | 2013-04-28 | | 公開日 | 2014-01-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex.
Sci Rep, 4, 2014
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3GDX
 | | Dna polymerase beta with a gapped DND substrate and dTMP(CF2)PP | | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | | 著者 | Wilson, S.H, Batra, V.K, Pedersen, L.C. | | 登録日 | 2009-02-24 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Alpha,beta-difluoromethylene deoxynucleoside 5'-triphosphates: a convenient synthesis of useful probes for DNA polymerase beta structure and function
Org.Lett., 11, 2009
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1DML
 | | CRYSTAL STRUCTURE OF HERPES SIMPLEX UL42 BOUND TO THE C-TERMINUS OF HSV POL | | 分子名称: | DNA POLYMERASE, DNA POLYMERASE PROCESSIVITY FACTOR | | 著者 | Zuccola, H.J, Filman, D.J, Coen, D.M, Hogle, J.M. | | 登録日 | 1999-12-14 | | 公開日 | 2000-03-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase.
Mol.Cell, 5, 2000
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1G6Q
 | | CRYSTAL STRUCTURE OF YEAST ARGININE METHYLTRANSFERASE, HMT1 | | 分子名称: | HNRNP ARGININE N-METHYLTRANSFERASE | | 著者 | Weiss, V.H, McBride, A.E, Soriano, M.A, Filman, D.J, Silver, P.A, Hogle, J.M. | | 登録日 | 2000-11-07 | | 公開日 | 2000-12-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The structure and oligomerization of the yeast arginine methyltransferase, Hmt1.
Nat.Struct.Biol., 7, 2000
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3KHW
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7OA4
 | | Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001 | | 分子名称: | (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, FORMIC ACID, MANGANESE (II) ION, ... | | 著者 | Feracci, M, Hernandez, S, Vincentelli, R, Ferron, F, Reguera, J, Canard, B, Alvarez, K. | | 登録日 | 2021-04-19 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001
To Be Published
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3PTO
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4LMO
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3MCT
 | | VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M3CYT AND S-ADENOSYLHOMOCYSTEINE | | 分子名称: | 3-METHYLCYTOSINE, S-ADENOSYL-L-HOMOCYSTEINE, VP39 | | 著者 | Hu, G, Gershon, P.D, Hodel, A.E, Quiocho, F.A. | | 登録日 | 1999-01-05 | | 公開日 | 1999-07-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains.
Proc.Natl.Acad.Sci.USA, 96, 1999
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3PR5
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1AKH
 | | MAT A1/ALPHA2/DNA TERNARY COMPLEX | | 分子名称: | DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MATING-TYPE PROTEIN A-1), ... | | 著者 | Li, T, Jin, Y, Vershon, A.K, Wolberger, C. | | 登録日 | 1997-05-19 | | 公開日 | 1998-05-20 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract.
Nucleic Acids Res., 26, 1998
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5T3W
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3M9M
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