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8IFD
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BU of 8ifd by Molmil
Dibekacin-added human 80S ribosome
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T.
登録日2023-02-17
公開日2024-02-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside.
J.Biochem., 175, 2024
8IFE
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BU of 8ife by Molmil
Arbekacin-added human 80S ribosome
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T.
登録日2023-02-17
公開日2024-02-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside.
J.Biochem., 175, 2024
8FC3
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BU of 8fc3 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and telithromycin at 2.60A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S.
登録日2022-12-01
公開日2023-07-12
最終更新日2025-03-19
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A.
Nat Commun, 14, 2023
9HNY
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BU of 9hny by Molmil
Mitoribosomal small subunit in complex with Mettl15 and Mettl17
分子名称: 30S ribosomal protein S8, 9S RNA, ACETYL COENZYME *A, ...
著者Zgadzay, Y, Aibara, S, Gahura, O, Amunts, A.
登録日2024-12-11
公開日2025-03-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mettl15-Mettl17 modulates the transition from early to late pre-mitoribosome.
Biorxiv, 2025
2ARP
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BU of 2arp by Molmil
Activin A in complex with Fs12 fragment of follistatin
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Follistatin, GLYCEROL, ...
著者Harrington, A.E, Morris-Triggs, S.A, Ruotolo, B.T, Robinson, C.V, Ohnuma, S, Hyvonen, M.
登録日2005-08-21
公開日2006-03-07
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the inhibition of activin signalling by follistatin
Embo J., 25, 2006
8FZI
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BU of 8fzi by Molmil
Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-B)
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
登録日2023-01-28
公開日2024-07-17
最終更新日2025-03-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 31, 2024
8FZJ
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BU of 8fzj by Molmil
Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-C)
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
登録日2023-01-28
公開日2024-07-17
最終更新日2025-03-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 31, 2024
6NWY
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BU of 6nwy by Molmil
Modified tRNA(Pro) bound to Thermus thermophilus 70S (near-cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
登録日2019-02-07
公開日2020-10-14
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NUO
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BU of 6nuo by Molmil
Modified tRNA(Pro) bound to Thermus thermophilus 70S (cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
登録日2019-02-01
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6YFT
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BU of 6yft by Molmil
Virus-like particle of Wenzhou levi-like virus 1
分子名称: RNA, coat protein
著者Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K.
登録日2020-03-26
公開日2020-09-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
6NSH
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BU of 6nsh by Molmil
Modified ASL proline bound to Thermus thermophilus 70S (near-cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M.
登録日2019-01-24
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.397 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6O3M
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BU of 6o3m by Molmil
Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
登録日2019-02-26
公開日2020-10-14
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.97 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NTA
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BU of 6nta by Molmil
Modified ASL proline bound to Thermus thermophilus 70S (cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M.
登録日2019-01-28
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6XHY
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BU of 6xhy by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with telithromycin, mRNA, aminoacylated A- and P-site tRNAs, and deacylated E-site tRNA at 2.60A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Svetlov, M.S, Syroegin, E.A, Aleksandrova, E.V, Atkinson, G.C, Gregory, S.T, Mankin, A.S, Polikanov, Y.S.
登録日2020-06-19
公開日2020-12-23
最終更新日2025-03-19
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance.
Nat.Chem.Biol., 17, 2021
5W4K
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BU of 5w4k by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with Klebsazolicin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Metelev, M, Osterman, I.A, Ghilarov, D, Khabibullina, N.F, Yakimov, A, Shabalin, K, Utkina, I, Travin, D.Y, Komarova, E.S, Serebryakova, M, Artamonova, T, Khodorkovskii, M, Konevega, A.L, Sergiev, P.V, Severinov, K, Polikanov, Y.S.
登録日2017-06-12
公開日2017-08-30
最終更新日2025-04-02
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.
Nat. Chem. Biol., 13, 2017
8FC6
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BU of 8fc6 by Molmil
Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and telithromycin at 2.35A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S.
登録日2022-12-01
公開日2023-07-26
最終更新日2025-03-19
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A.
Nat Commun, 14, 2023
9IJJ
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BU of 9ijj by Molmil
In situ structure of the central apparatus in mouse sperm axoneme.
分子名称: Ankyrin repeat and MYND domain-containing protein 1, Calmodulin-1, Cilia and flagella associated protein 46, ...
著者Zhu, Y, Yin, G, Sun, F.
登録日2024-06-23
公開日2025-06-04
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Cryo-EM structure of the native central apparatus in mouse sperm axoneme
To Be Published
5O61
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BU of 5o61 by Molmil
The complete structure of the Mycobacterium smegmatis 70S ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hentschel, J, Burnside, C, Mignot, I, Leibundgut, M, Boehringer, D, Ban, N.
登録日2017-06-03
公開日2017-07-12
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献The Complete Structure of the Mycobacterium smegmatis 70S Ribosome.
Cell Rep, 20, 2017
8IFC
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BU of 8ifc by Molmil
Arbekacin-bound E.coli 70S ribosome in the PURE system
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T.
登録日2023-02-17
公開日2024-02-14
最終更新日2025-02-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside.
J.Biochem., 175, 2024
7KGB
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BU of 7kgb by Molmil
CryoEM structure of A2296-methylated Mycobacterium tuberculosis ribosome bound with SEQ-9
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Cui, Z, Zhang, J.
登録日2020-10-16
公開日2022-01-19
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents.
Cell, 2023
5WFS
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BU of 5wfs by Molmil
70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Frank, J.
登録日2017-07-12
公開日2018-05-02
最終更新日2025-02-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WF0
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BU of 5wf0 by Molmil
70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Frank, J.
登録日2017-07-11
公開日2018-05-02
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
7Z3N
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BU of 7z3n by Molmil
Cryo-EM structure of the ribosome-associated RAC complex on the 80S ribosome - RAC-1 conformation
分子名称: 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ...
著者Kisonaite, M, Wild, K, Sinning, I.
登録日2022-03-02
公開日2023-04-12
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural inventory of cotranslational protein folding by the eukaryotic RAC complex.
Nat.Struct.Mol.Biol., 30, 2023
5HCP
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BU of 5hcp by Molmil
Crystal structure of antimicrobial peptide Metalnikowin bound to the Thermus thermophilus 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A.
登録日2016-01-04
公開日2016-04-06
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.894 Å)
主引用文献Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.
Nucleic Acids Res., 44, 2016
4TUA
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BU of 4tua by Molmil
Crystal structure of ASL-Thr bound to Codon ACC-A on the Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fagan, C.E, Dunham, C.M.
登録日2014-06-24
公開日2015-05-13
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural insights into translational recoding by frameshift suppressor tRNASufJ.
Rna, 20, 2014

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件を2025-07-09に公開中

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