PDB: 438 件ウェブページステータス検索Chemie searchBIRD

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6CE9	Insulin Receptor ectodomain in complex with two insulin molecules 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
6CEB	Insulin Receptor ectodomain in complex with two insulin molecules - C1 symmetry 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
6CE7	Insulin Receptor ectodomain in complex with one insulin molecule 分子名称: Insulin A chain, Insulin B chain, Insulin receptor, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
6SOF	human insulin receptor ectodomain bound by 4 insulin 分子名称: Insulin, Insulin receptor 著者 Gutmann, T, Schaefer, I.B, Poojari, C.S, Vattulainen, I, Strauss, M, Coskun, U. 登録日 2019-08-29 公開日 2019-11-13 最終更新日 2020-05-27 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain. J.Cell Biol., 219, 2020
7SL6	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- symmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL7	Full-length insulin receptor bound with both site 1 binding deficient mutant insulin (A-V3E) and site 2 binding deficient mutant insulin (A-L13R) 分子名称: Insulin A chain (L13R), Insulin A chain (V3E), Insulin B chain, ... 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL2	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- asymmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL3	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- symmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL4	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- asymmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL1	Full-length insulin receptor bound with site 1 binding deficient mutant insulin (A-V3E) 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7S0Q	Head region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ... 著者 Xu, Y, Lawrence, M.C. 登録日 2021-08-30 公開日 2022-07-06 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor. Structure, 30, 2022
7QID	tentative model of the human insulin receptor ectodomain bound by three insulin 分子名称: Insulin, Insulin receptor, Isoform Short of Insulin receptor 著者 Gutman, T, Schaefer, I.B, Poojari, C.S, Vattulainen, I, Strauss, M, Coskun, U. 登録日 2021-12-14 公開日 2022-02-02 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain J Cell Biol, 219, 2020
2V5P	COMPLEX STRUCTURE OF HUMAN IGF2R DOMAINS 11-13 BOUND TO IGF-II 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, INSULIN-LIKE GROWTH FACTOR II, ... 著者 Brown, J, Delaine, C, Zaccheo, O.J, Siebold, C, Gilbert, R.J, van Boxel, G, Denley, A, Wallace, J.C, Hassan, A.B, Forbes, B.E, Jones, E.Y. 登録日 2007-07-06 公開日 2007-12-11 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Structure and Functional Analysis of the Igf-II/Igf2R Interaction Embo J., 27, 2008

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