PDB: 437 件ウェブページステータス検索Chemie searchBIRD

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7SL7	Full-length insulin receptor bound with both site 1 binding deficient mutant insulin (A-V3E) and site 2 binding deficient mutant insulin (A-L13R) 分子名称: Insulin A chain (L13R), Insulin A chain (V3E), Insulin B chain, ... 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL1	Full-length insulin receptor bound with site 1 binding deficient mutant insulin (A-V3E) 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL4	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- asymmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL3	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- symmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL2	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- asymmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL6	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- symmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7S0Q	Head region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ... 著者 Xu, Y, Lawrence, M.C. 登録日 2021-08-30 公開日 2022-07-06 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor. Structure, 30, 2022
6PXV	Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the extracellular region. 分子名称: Insulin, Insulin receptor 著者 Uchikawa, E, Choi, E, Shang, G.J, Yu, H.T, Bai, X.C. 登録日 2019-07-27 公開日 2019-09-04 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. Elife, 8, 2019
6PYH	Cryo-EM structure of full-length IGF1R-IGF1 complex. Only the extracellular region of the complex is resolved. 分子名称: Insulin-like growth factor 1 receptor, Insulin-like growth factor I 著者 Li, J, Choi, E, Yu, H.T, Bai, X.C. 登録日 2019-07-29 公開日 2019-10-23 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural basis of the activation of type 1 insulin-like growth factor receptor. Nat Commun, 10, 2019
6PXW	Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the top part of the receptor complex. 分子名称: Insulin, Insulin receptor 著者 Uchikawa, E, Choi, E, Shang, G.J, Yu, H.T, Bai, X.C. 登録日 2019-07-28 公開日 2019-09-04 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. Elife, 8, 2019
2V5P	COMPLEX STRUCTURE OF HUMAN IGF2R DOMAINS 11-13 BOUND TO IGF-II 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, INSULIN-LIKE GROWTH FACTOR II, ... 著者 Brown, J, Delaine, C, Zaccheo, O.J, Siebold, C, Gilbert, R.J, van Boxel, G, Denley, A, Wallace, J.C, Hassan, A.B, Forbes, B.E, Jones, E.Y. 登録日 2007-07-06 公開日 2007-12-11 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Structure and Functional Analysis of the Igf-II/Igf2R Interaction Embo J., 27, 2008
5U8Q	Structure of the ectodomain of the human Type 1 insulin-like growth factor receptor in complex with IGF-I 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-MALATE, ... 著者 Lawrence, M, Xu, Y. 登録日 2016-12-14 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.2710402 Å) 主引用文献 How ligand binds to the type 1 insulin-like growth factor receptor. Nat Commun, 9, 2018

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