4ZJY
 
 | |
5JIO
 | | Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase ternary complex with ADP and Glucose-6-phosphate. | | 分子名称: | 1,2-ETHANEDIOL, 6-O-phosphono-alpha-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Mendes, V, Verma, N, Blaszczyk, M, Blundell, T.L. | | 登録日 | 2016-04-22 | | 公開日 | 2017-05-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.711 Å) | | 主引用文献 | Mycobacterial OtsA Structures Unveil Substrate Preference Mechanism and Allosteric Regulation by 2-Oxoglutarate and 2-Phosphoglycerate.
Mbio, 10, 2019
|
|
6X9O
 | | High resolution cryoEM structure of huntingtin in complex with HAP40 | | 分子名称: | 40-kDa huntingtin-associated protein, Huntingtin | | 著者 | Harding, R.J, Deme, J.C, Lea, S.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | 登録日 | 2020-06-03 | | 公開日 | 2020-06-17 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1.
Commun Biol, 4, 2021
|
|
8Q6U
 | |
6E1S
 | | Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 1: 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine | | 分子名称: | 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine, RNA (33-MER) | | 著者 | Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. | | 登録日 | 2018-07-10 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure.
Nat Commun, 10, 2019
|
|
6E1T
 | | Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 1: 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine, MAGNESIUM ION, ... | | 著者 | Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. | | 登録日 | 2018-07-10 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure.
Nat Commun, 10, 2019
|
|
6RA5
 | | Human tnik in complex with compound 9 | | 分子名称: | 5-bromanyl-2-(2-fluoranylpyridin-4-yl)-1,7-naphthyridin-8-amine, MAGNESIUM ION, TRAF2 and NCK-interacting protein kinase | | 著者 | Read, J.A. | | 登録日 | 2019-04-05 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinase
To Be Published
|
|
6XKT
 | | R. capsulatus cyt bc1 with both FeS proteins in c position (CIII2 c-c) | | 分子名称: | Cytochrome b, Cytochrome c1, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Steimle, S, Van Eeuwen, T, Ozturk, Y, Kim, H.J, Braitbard, M, Selamoglu, N, Garcia, B.A, Schneidman-Duhovny, D, Murakami, K, Daldal, F. | | 登録日 | 2020-06-27 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Cryo-EM structures of engineered active bc 1 -cbb 3 type CIII 2 CIV super-complexes and electronic communication between the complexes.
Nat Commun, 12, 2021
|
|
8Q29
 | |
6R4U
 | |
6HPY
 | | Crystal structure of ENL (MLLT1) in complex with compound 12 | | 分子名称: | 1,2-ETHANEDIOL, 3-[4-[(4-~{tert}-butylphenyl)carbonylamino]phenyl]propanoic acid, Protein ENL, ... | | 著者 | Heidenreich, D, Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2018-09-22 | | 公開日 | 2018-11-28 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL).
J.Med.Chem., 61, 2018
|
|
3TEU
 | | Crystal structure of fibcon | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, Fibcon | | 著者 | Luo, J, Jacobs, S, Teplyakov, A, Obmolova, G, O'Neil, K, Gilliland, G. | | 登録日 | 2011-08-15 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.002 Å) | | 主引用文献 | Design of novel FN3 domains with high stability by a consensus sequence approach.
Protein Eng.Des.Sel., 25, 2012
|
|
6YZF
 | | Crystal structure of the M295Y variant of Ssl1 | | 分子名称: | COPPER (II) ION, Copper oxidase, GLU-HIS-SER, ... | | 著者 | Mielenbrink, S, Olbrich, A, Urlacher, V, Span, I. | | 登録日 | 2020-05-06 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-12-04 | | 実験手法 | X-RAY DIFFRACTION (1.684 Å) | | 主引用文献 | Substitution of the axial Type 1 Cu Ligand Afford Binding of a Water Molecule in Axial Position Affecting Kinetics, Spectral, and Structural Properties of the Small Laccase Ssl1.
Chemistry, 2024
|
|
7B53
 | | Crystal structure of MurE from E.coli | | 分子名称: | 1,2-ETHANEDIOL, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase | | 著者 | Koekemoer, L, Steindel, M, Fairhead, M, Talon, R, Douangamath, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Krojer, T, Structural Genomics Consortium (SGC) | | 登録日 | 2020-12-03 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of MurE from E.coli
To Be Published
|
|
8J3J
 | | Crystal structure of a bright green fluorescent protein (StayGold) with double mutations (Q140S, Y187F) in jellyfish Cytaeis uchidae from Biortus | | 分子名称: | 1,2-ETHANEDIOL, StayGold(Q140S, Y187F) | | 著者 | Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y. | | 登録日 | 2023-04-17 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus
To Be Published
|
|
6YZD
 | | Crystal structure of the M295A variant of Ssl1 | | 分子名称: | COPPER (II) ION, Copper oxidase, SULFATE ION | | 著者 | Mielenbrink, S, Olbrich, A, Urlacher, V, Span, I. | | 登録日 | 2020-05-06 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-12-04 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Substitution of the axial Type 1 Cu Ligand Afford Binding of a Water Molecule in Axial Position Affecting Kinetics, Spectral, and Structural Properties of the Small Laccase Ssl1.
Chemistry, 2024
|
|
9IIO
 | |
9IQO
 | |
6YZY
 | | Crystal structure of the M295V variant of Ssl1 | | 分子名称: | COPPER (II) ION, Copper oxidase, SULFATE ION | | 著者 | Mielenbrink, S, Olbrich, A, Urlacher, V, Span, I. | | 登録日 | 2020-05-07 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-12-04 | | 実験手法 | X-RAY DIFFRACTION (2.282 Å) | | 主引用文献 | Substitution of the axial Type 1 Cu Ligand Afford Binding of a Water Molecule in Axial Position Affecting Kinetics, Spectral, and Structural Properties of the Small Laccase Ssl1.
Chemistry, 2024
|
|
7RYV
 | |
8QNX
 | | OPR3 variant with redesigned loop 6 (8aa) in complex with NADH4 | | 分子名称: | 1,4,5,6-Tetrahydronicotinamide adenine dinucleotide, 12-oxophytodienoate reductase 3, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Bijelic, A, Macheroux, P, Kerschbaumer, B. | | 登録日 | 2023-09-27 | | 公開日 | 2025-04-09 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal structures of OPR3 wildtype and variants in complex with NAD(P)H
To Be Published
|
|
8QJ1
 | |
6MO0
 | | Structure of dengue virus protease with an allosteric Inhibitor that blocks replication | | 分子名称: | 1-(4-{3-[4-(furan-3-yl)phenyl]-5-[(piperidin-4-yl)methoxy]pyrazin-2-yl}phenyl)methanamine, FLAVIVIRUS_NS2B/Peptidase S7 | | 著者 | Lin, Y.-L, Nie, S, Hua, Y, Wu, J, Wu, F, Huo, T, Yao, Y, Song, Y. | | 登録日 | 2018-10-03 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
J. Am. Chem. Soc., 141, 2019
|
|
7SKL
 | | Complex between S. aureus aureolysin and IMPI mutant I57I | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, IMPI alpha, ... | | 著者 | Mendes, S.R, Eckhard, U, Rodriguez-Banqueri, A, Guevara, T, Gomis-Ruth, F.X. | | 登録日 | 2021-10-21 | | 公開日 | 2022-01-26 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | An engineered protein-based submicromolar competitive inhibitor of the Staphylococcus aureus virulence factor aureolysin
Comput Struct Biotechnol J, 20, 2022
|
|
6MOT
 | |
