PDB: 41592 件ウェブページステータス検索Chemie searchBIRD

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6CFI	Crystal structure of Rad4-Rad23 bound to a 6-4 photoproduct UV lesion 分子名称: DNA (5'-D(*AP*TP*TP*GP*TP*AP*GP*CP*(T64)P*TP*GP*GP*AP*TP*GP*TP*TP*GP*AP*GP*TP*CP*A)-3'), DNA repair protein RAD4, DNA('-D(*TP*TP*GP*AP*CP*TP*CP*AP*AP*CP*AP*TP*CP*CP*AP*AP*AP*GP*CP*TP*AP*CP*AP*A)-'), ... 著者 Min, J, Jeffrey, P.D. 登録日 2018-02-15 公開日 2019-02-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.36241913 Å) 主引用文献 Structure and mechanism of pyrimidine-pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex. Nucleic Acids Res., 47, 2019
5WMT	Structure of GRP94 N-terminal Domain bound to resorcinylic inhibitor BnIm. 分子名称: 1,2-ETHANEDIOL, Endoplasmin, MAGNESIUM ION, ... 著者 Que, N.S, Gewirth, D.T. 登録日 2017-07-31 公開日 2018-04-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.748 Å) 主引用文献 Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding. J. Med. Chem., 61, 2018
5W9N	MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4 分子名称: G4 VH, G4 VL, MERS S 著者 Pallesen, J, Ward, A.B. 登録日 2017-06-23 公開日 2017-08-16 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UQX	USP7 in complex with GNE6776 (6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide) 分子名称: 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl[3,3'-bipyridine]-6-carboxamide, Ubiquitin carboxyl-terminal hydrolase 7 著者 Murray, J.M, Rouge, L. 登録日 2017-02-08 公開日 2017-10-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature, 550, 2017
4DXS	Human SUN2-KASH2 complex 分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, Nesprin-2, POTASSIUM ION, ... 著者 Sosa, B, Schwartz, T.U. 登録日 2012-02-28 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins. Cell(Cambridge,Mass.), 149, 2012
3VVW	NDP52 in complex with LC3C 分子名称: Calcium-binding and coiled-coil domain-containing protein 2, Microtubule-associated proteins 1A/1B light chain 3C 著者 Akutsu, M, Muhlinen, N.V, Randow, F, Komander, D. 登録日 2012-07-28 公開日 2013-02-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy Mol.Cell, 48, 2012
3N52	crystal Structure analysis of MIP2 分子名称: C-X-C motif chemokine 2 著者 Rajasekaran, D. 登録日 2010-05-24 公開日 2011-06-08 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Model of GAG/MIP-2/CXCR2 Interfaces and Its Functional Effects. Biochemistry, 51, 2012
5XKF	Crystal structure of T2R-TTL-MPC6827 complex 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... 著者 Wang, Y, Yang, J, Wang, T, Chen, L. 登録日 2017-05-07 公開日 2018-04-18 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Identification of a powerful and reversible microtubule-inhibitor with efficacy against multidrug-resistant tumors To Be Published
5X9C	Crystal structure of the cytosolic domain of human MiD51 分子名称: Mitochondrial dynamics protein MID51 著者 Sun, F, Pang, X, Ma, J. 登録日 2017-03-06 公開日 2018-03-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 New interfaces on MiD51 for Drp1 recruitment and mitochondrial fission regulation To Be Published
3IDB	Crystal structure of (108-268)RIIb:C holoenzyme of cAMP-dependent protein kinase 分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Brown, S.H.J, Wu, J, Kim, C, Alberto, K, Taylor, S.S. 登録日 2009-07-20 公開日 2009-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures. J.Mol.Biol., 393, 2009
5W9K	MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4 分子名称: G4 VH, G4 VL, Spike glycoprotein 著者 Pallesen, J, Ward, A.B. 登録日 2017-06-23 公開日 2017-08-16 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5XKE	Crystal structure of T2R-TTL-Demecolcine complex 分子名称: (7S)-1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Wang, Y, Yang, J, Wang, T, Chen, L. 登録日 2017-05-07 公開日 2018-07-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Identification of a powerful and reversible microtubule-inhibitor with efficacy against multidrug-resistant tumors To Be Published
3IDC	Crystal structure of (102-265)RIIb:C holoenzyme of cAMP-dependent protein kinase 分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Brown, S.H.J, Wu, J, Kim, C, Alberto, K, Taylor, S.S. 登録日 2009-07-20 公開日 2009-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures. J.Mol.Biol., 393, 2009
5X9B	Crystal structure of the cytosolic domain of human MiD51 分子名称: Mitochondrial dynamics protein MID51 著者 Sun, F, Pang, X, Ma, J. 登録日 2017-03-06 公開日 2018-04-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 New interfaces on MiD51 for Drp1 recruitment and regulation. Plos One, 14, 2019
1HPL	HORSE PANCREATIC LIPASE. THE CRYSTAL STRUCTURE AT 2.3 ANGSTROMS RESOLUTION 分子名称: CALCIUM ION, LIPASE 著者 Bourne, Y, Cambillau, C. 登録日 1993-01-27 公開日 1994-05-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Horse pancreatic lipase. The crystal structure refined at 2.3 A resolution. J.Mol.Biol., 238, 1994
2Q31	Actin Dimer Cross-linked Between Residues 41 and 374 and proteolytically cleaved by subtilisin between residues 47 and 48. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Sawaya, M.R, Pashkov, I, Kudryashov, D.S, Reisler, E, Yeates, T.O. 登録日 2007-05-29 公開日 2007-06-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Multiple crystal structures of actin dimers and their implications for interactions in the actin filament. Acta Crystallogr.,Sect.D, 64, 2008
4HLL	Crystal structure of Artificial ankyrin repeat protein_Ank(GAG)1D4 分子名称: Ankyrin(GAG)1D4 著者 Chuankhayan, P, Nangola, S, Minard, P, Boulanger, P, Hong, S.S, Tayapiwatana, C, Chen, C.-J. 登録日 2012-10-17 公開日 2013-10-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Identification of Gag bioactive determinants specific to designed ankyrin and interfering in HIV-1 assembly To be Published
3TT9	Crystal structure of the stable degradation fragment of human plakophilin 2 isoform a (PKP2a) C752R variant 分子名称: GLYCEROL, Plakophilin-2 著者 Schuetz, A, Roske, Y, Gerull, B, Heinemann, U. 登録日 2011-09-14 公開日 2012-08-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations. Circ Cardiovasc Genet, 5, 2012
1GA1	CRYSTAL STRUCTURE ANALYSIS OF PSCP (PSEUDOMONAS SERINE-CARBOXYL PROTEINASE) COMPLEXED WITH A FRAGMENT OF IODOTYROSTATIN (THIS ENZYME RENAMED "SEDOLISIN" IN 2003) 分子名称: CALCIUM ION, CHLORIDE ION, FRAGMENT OF IODOTYROSTATIN, ... 著者 Dauter, Z, Li, M, Wlodawer, A. 登録日 2000-11-29 公開日 2000-12-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Practical experience with the use of halides for phasing macromolecular structures: a powerful tool for structural genomics. Acta Crystallogr.,Sect.D, 57, 2001
3UZY	Crystal structure of 5beta-reductase (AKR1D1) E120H mutant in complex with NADP+ and 5beta-dihydrotestosterone 分子名称: 3-oxo-5-beta-steroid 4-dehydrogenase, 5-beta-DIHYDROTESTOSTERONE, CHLORIDE ION, ... 著者 Chen, M, Christianson, D.W, Penning, T.M. 登録日 2011-12-07 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.832 Å) 主引用文献 Conversion of Human Steroid 5beta-Reductase (AKR1D1) into 3β-Hydroxysteroid Dehydrogenase by Single Point Mutation E120H: EXAMPLE OF PERFECT ENZYME ENGINEERING. J.Biol.Chem., 287, 2012
3SE9	Crystal structure of broadly and potently neutralizing antibody VRC-PG04 in complex with HIV-1 gp120 分子名称: (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kwong, P.D, Zhou, T. 登録日 2011-06-10 公開日 2011-08-10 最終更新日 2021-04-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science, 333, 2011
2GR1	Crystal structure of Ferredoxin reductase, BphA4 (hydroquinone) 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, ferredoxin reductase 著者 Senda, T, Senda, M. 登録日 2006-04-22 公開日 2007-05-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A ferredoxin reductase BphA4 uses a butterfly motion of FAD to regulate affinity for ferredoxin To be Published
2GR3	Crystal structure of Ferredoxin reductase, BphA4 (oxidized form) 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, GLYCEROL, ... 著者 Senda, T, Senda, M. 登録日 2006-04-22 公開日 2007-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A ferredoxin reductase BphA4 uses a butterfly motion of FAD to regulate affinity for ferredoxin To be Published
4AGN	Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5116 分子名称: 2-{[4-(DIETHYLAMINO)PIPERIDIN-1-YL]METHYL}-4-(3-HYDROXYPROP-1-YN-1-YL)-6-IODOPHENOL, CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Joerger, A.C, Wilcken, R, Boeckler, F.M, Fersht, A.R. 登録日 2012-01-30 公開日 2012-03-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53. J.Am.Chem.Soc., 134, 2012
2LBC	solution structure of tandem UBA of USP13 分子名称: Ubiquitin carboxyl-terminal hydrolase 13 著者 Zhang, Y, Zhou, C, Zhou, Z, Song, A, Hu, H. 登録日 2011-03-29 公開日 2012-03-07 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Domain Analysis Reveals That a Deubiquitinating Enzyme USP13 Performs Non-Activating Catalysis for Lys63-Linked Polyubiquitin. Plos One, 6, 2011

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