PDB: 45522 件ウェブページステータス検索Chemie searchBIRD

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3GG1	Klebsiella pneumoniae BlrP1 pH 8.0 calcium/cy-diGMP complex 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, FLAVIN MONONUCLEOTIDE, ... 著者 Barends, T, Hartmann, E, Griese, J, Beitlich, T, Kirienko, N, Ryjenkov, D, Reinstein, J, Shoeman, R, Gomelsky, M, Schlichting, I. 登録日 2009-02-27 公開日 2009-06-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase. Nature, 459, 2009
2R3J	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor 分子名称: 3-bromo-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine, Cell division protein kinase 2 著者 Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. 登録日 2007-08-29 公開日 2008-01-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
3QP0	HIV-1 protease (mutant Q7K L33I L63I) in complex with a novel inhibitor 分子名称: (4aS,7aS)-1,4-bis[3-(hydroxymethyl)benzyl]hexahydro-1H-pyrrolo[3,4-b]pyrazine-2,3-dione, CHLORIDE ION, Protease 著者 Lindemann, I, Heine, A, Klebe, G. 登録日 2011-02-11 公開日 2012-02-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Novel inhibitors for HIV-1 protease To be Published
2QCW	Crystal Structure of Bone Morphogenetic Protein-6 (BMP-6) 分子名称: Bone morphogenetic protein 6 著者 Allendorph, G.P. 登録日 2007-06-19 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 BMP-3 and BMP-6 Structures Illuminate the Nature of Binding Specificity with Receptors. Biochemistry, 46, 2007
3G0B	Crystal structure of dipeptidyl peptidase IV in complex with TAK-322 分子名称: 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Zhang, Z, Wallace, M.B, Feng, J, Stafford, J.A, Kaldor, S.W, Shi, L, Skene, R.J, Aertgeerts, K, Lee, B, Jennings, A, Xu, R, Kassel, D, Webb, D.R, Gwaltney, S.L. 登録日 2009-01-27 公開日 2010-02-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Design and Synthesis of Pyrimidinone and Pyrimidinedione Inhibitors of Dipeptidyl Peptidase IV. J.Med.Chem., 54, 2011
3QRM	HIV-1 protease (mutant Q7K L33I L63I) in complex with a three-armed pyrrolidine-based inhibitor 分子名称: 4-{[4-(trifluoromethyl)benzyl][(3S,4S)-4-{[4-(trifluoromethyl)benzyl]amino}pyrrolidin-3-yl]sulfamoyl}benzamide, CHLORIDE ION, DITHIANE DIOL, ... 著者 Lindemann, I, Heine, A, Klebe, G. 登録日 2011-02-18 公開日 2012-02-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.731 Å) 主引用文献 Design of a series of novel three-armed pyrrolidine-based inhibitors for HIV-1 protease To be Published
2QFX	Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADPH, a-ketoglutarate and Ca(2+) 分子名称: 2-OXOGLUTARIC ACID, CALCIUM ION, Isocitrate dehydrogenase [NADP], ... 著者 Peng, Y.J, Ding, J.P. 登録日 2007-06-28 公開日 2008-07-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction Protein Sci., 17, 2008
3QBN	Structure of Human Aurora A in Complex with a diaminopyrimidine 分子名称: 5-chloro-N~4~-cyclopropyl-N~2~-[4-(2-methoxyethoxy)phenyl]pyrimidine-2,4-diamine, Serine/threonine-protein kinase 6 著者 Gruetter, C, Simard, J.R, Rauh, D. 登録日 2011-01-13 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Identification of Ustilago maydis Aurora kinase as a novel antifungal target. Acs Chem.Biol., 6, 2011
3G9B	Crystal structure of reduced Ost6L 分子名称: Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST6 著者 Stirnimann, C.U, Grimshaw, J.P.A, Schulz, B.L, Brozzo, M.S, Fritsch, F, Glockshuber, R, Capitani, G, Gruetter, M.G, Aebi, M. 登録日 2009-02-13 公開日 2009-06-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency. Proc.Natl.Acad.Sci.USA, 106, 2009
2XMZ	Structure of MenH from S. aureus 分子名称: HYDROLASE, ALPHA/BETA HYDROLASE FOLD FAMILY 著者 Dawson, A, Fyfe, P.K, Gillet, F, Hunter, W.N. 登録日 2010-07-30 公開日 2011-05-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Exploiting the High-Resolution Crystal Structure of Staphylococcus Aureus Menh to Gain Insight Into Enzyme Activity. Bmc Struct.Biol., 11, 2011
3QF4	Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation 分子名称: ABC transporter, ATP-binding protein, MAGNESIUM ION, ... 著者 Hohl, M, Briand, C, Gruetter, M.G, Seeger, M.A. 登録日 2011-01-21 公開日 2012-03-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation Nat.Struct.Mol.Biol., 19, 2012
2XF5	Crystal structure of Bacillus subtilis SPP1 phage gp23.1, a putative chaperone. 分子名称: GP23.1 著者 Veesler, D, Blangy, S, Lichiere, J, Ortiz-Lombardia, M, Tavares, P, Campanacci, V, Cambillau, C. 登録日 2010-05-20 公開日 2010-08-11 最終更新日 2017-07-12 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Bacillus Subtilis Spp1 Phage Gp23.1, A Putative Chaperone. Protein Sci., 19, 2010
2XGT	Asparaginyl-tRNA synthetase from Brugia malayi complexed with the sulphamoyl analogue of asparaginyl-adenylate 分子名称: 5'-O-[N-(L-ASPARAGINYL)SULFAMOYL]ADENOSINE, ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC, ... 著者 Crepin, T, Haertlein, M, Kron, M, Cusack, S. 登録日 2010-06-07 公開日 2010-12-15 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Hybrid Structural Model of the Complete Brugia Malayi Cytoplasmic Asparaginyl-tRNA Synthetase. J.Mol.Biol., 405, 2011
3GGK	Locating monovalent cations in one turn of G/C rich B-DNA 分子名称: 5'-D(*CP*CP*AP*GP*GP*CP*CP*TP*GP*G) -3', MAGNESIUM ION, RUBIDIUM ION 著者 Maehigashi, T, Moulaei, T, Watkins, D, Komeda, S, Williams, L.D. 登録日 2009-02-28 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (0.87 Å) 主引用文献 Locating monovalent cations in one turn of G/C rich B-DNA To be Published
2XHJ	Circular permutation provides an evolutionary link between two families of calcium-dependent carbohydrate binding modules. SeMet form of vCBM60. 分子名称: CALCIUM ION, CALCIUM-DEPENDENT CARBOHYDRATE BINDING MODULE 著者 Montanier, C, Flint, J.E, Bolam, D.N, Xie, H, Liu, Z, Rogowski, A, Weiner, D, Ratnaparkhe, S, Nurizzo, D, Roberts, S.M, Turkenburg, J.P, Davies, G.J, Gilbert, H.J. 登録日 2010-06-16 公開日 2010-07-21 最終更新日 2019-05-08 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-Dependent Carbohydrate Binding Modules J.Biol.Chem., 285, 2010
3QI3	Crystal structure of PDE9A(Q453E) in complex with inhibitor BAY73-6691 分子名称: 1-(2-chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... 著者 Hou, J, Xu, J, Liu, M, Zhao, R, Lou, H, Ke, H. 登録日 2011-01-26 公開日 2011-04-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic Acid, and role of the invariant glutamine. Plos One, 6, 2011
2XUF	CRYSTAL STRUCTURE OF MACHE-Y337A-TZ2PA6 ANTI COMPLEX (1 MTH) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,8-DIAMINO-6-PHENYL-5-[6-[1-[2-[(1,2,3,4-TETRAHYDRO-9-ACRIDINYL)AMINO]ETHYL]-1H-1,2,3-TRIAZOL-4-YL]HEXYL]-PHENANTHRIDINIUM, ACETYLCHOLINESTERASE, ... 著者 Bourne, Y, Radic, Z, Taylor, P, Marchot, P. 登録日 2010-10-19 公開日 2010-12-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Conformational Remodeling of Femtomolar Inhibitor-Acetylcholinesterase Complexes in the Crystalline State J.Am.Chem.Soc., 132, 2010
2XHH	Circular permutation provides an evolutionary link between two families of calcium-dependent carbohydrate binding modules 分子名称: (2S)-2-hydroxybutanedioic acid, CALCIUM ION, CARBOHYDRATE BINDING MODULE 著者 Montanier, C, Flint, J.E, Bolam, D.N, Xie, H, Liu, Z, Rogowski, A, Weiner, D, Ratnaparkhe, S, Nurizzo, D, Roberts, S.M, Turkenburg, J.P, Davies, G.J, Gilbert, H.J. 登録日 2010-06-16 公開日 2010-07-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-Dependent Carbohydrate Binding Modules J.Biol.Chem., 285, 2010
3DE1	Proteinase K by LB nanotemplate method after the third step of high X-Ray dose on ESRF ID23-1 beamline 分子名称: CALCIUM ION, Proteinase K 著者 Pechkova, E, Tripathi, S.K, Nicolini, C. 登録日 2008-06-07 公開日 2009-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Radiation stability of proteinase K crystals grown by LB nanotemplate method J.Struct.Biol., 168, 2009
3DDZ	Proteinase K by LB nanotemplate method after the first step of high X-Ray dose on ESRF ID23-1 beamline 分子名称: CALCIUM ION, Proteinase K 著者 Pechkova, E, Tripathi, S.K, Nicolini, C. 登録日 2008-06-07 公開日 2009-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Radiation stability of proteinase K crystals grown by LB nanotemplate method J.Struct.Biol., 168, 2009
3QA9	Crystal Structure of Prb (PH1109 protein redesigned for binding) 分子名称: CoA binding domain protein 著者 Spiegel, P.C. 登録日 2011-01-10 公開日 2011-04-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A de novo protein binding pair by computational design and directed evolution. Mol.Cell, 42, 2011
3D9Q	Proteinase K by LB nanotemplate method before high X-Ray dose on ESRF ID23-1 beamline 分子名称: CALCIUM ION, Proteinase K 著者 Pechkova, E, Tripathi, S.K, Nicolini, C. 登録日 2008-05-27 公開日 2009-06-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Radiation stability of proteinase K crystals grown by LB nanotemplate method J.Struct.Biol., 168, 2009
2XGV	Structure of the N-terminal domain of capsid protein from Rabbit Endogenous Lentivirus (RELIK) 分子名称: PSIV CAPSID N-TERMINAL DOMAIN 著者 Goldstone, D.C, Robertson, L.E, Haire, L.F, Stoye, J.P, Taylor, I.A. 登録日 2010-06-07 公開日 2010-09-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface. Cell Host Microbe, 8, 2010
3DE0	Proteinase K by LB nanotemplate method after the second step of high X-Ray dose on ESRF ID23-1 beamline 分子名称: CALCIUM ION, Proteinase K 著者 Pechkova, E, Tripathi, S.K, Nicolini, C. 登録日 2008-06-07 公開日 2009-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Radiation stability of proteinase K crystals grown by LB nanotemplate method J.Struct.Biol., 168, 2009
3DE2	Proteinase K by LB nanotemplate method after the fourth step of high X-Ray dose on ESRF ID23-1 beamline 分子名称: CALCIUM ION, Proteinase K 著者 Pechkova, E, Tripathi, S.K, Nicolini, C. 登録日 2008-06-07 公開日 2009-06-09 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Radiation stability of proteinase K crystals grown by LB nanotemplate method J.Struct.Biol., 168, 2009

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