PDB: 243911 件ウェブページステータス検索Chemie searchBIRD

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5W4W	Identification and Profiling of a Selective and Brain Penetrant Radioligand for In Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors 分子名称: 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-6-methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one, Casein kinase I isoform delta, SULFATE ION 著者 Liu, S. 登録日 2017-06-13 公開日 2017-06-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Identification and Profiling of a Selective and Brain Penetrant Radioligand for in Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors. ACS Chem Neurosci, 8, 2017
5W5E	Re-refinement of the pyocin tube structure 分子名称: FIIR2 protein 著者 Wang, F, Zheng, W, Taylor, N.M, Guerrero-Ferreira, R.C, Leiman, P.G, Egelman, E.H. 登録日 2017-06-15 公開日 2017-08-16 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Refined Cryo-EM Structure of the T4 Tail Tube: Exploring the Lowest Dose Limit. Structure, 25, 2017
6D23	GLUCOSE-6-P DEHYDROGENASE (APO FORM) FROM TRYPANOSOMA CRUZI 分子名称: CHLORIDE ION, GLYCEROL, Glucose-6-phosphate 1-dehydrogenase, ... 著者 Botti, H, Ortiz, C, Comini, M.A, Larrieux, N, Buschiazzo, A. 登録日 2018-04-12 公開日 2018-05-02 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation. J.Mol.Biol., 431, 2019
5VXY	Cryo-EM reconstruction of PAK pilus from Pseudomonas aeruginosa 分子名称: Fimbrial protein 著者 Wang, F, Osinksi, T, Orlova, A, Altindal, T, Craig, L, Egelman, E.H. 登録日 2017-05-24 公開日 2017-07-12 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Cryoelectron Microscopy Reconstructions of the Pseudomonas aeruginosa and Neisseria gonorrhoeae Type IV Pili at Sub-nanometer Resolution. Structure, 25, 2017
5VYL	Crystal Structure of N-terminal half of Herpes Simplex virus Type 1 UL37 protein 分子名称: Inner tegument protein, SODIUM ION 著者 Koenigsberg, A, Heldwein, E.E. 登録日 2017-05-25 公開日 2017-08-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.51 Å) 主引用文献 Crystal Structure of the N-Terminal Half of the Traffic Controller UL37 from Herpes Simplex Virus 1. J. Virol., 91, 2017
5VYR	Crystal structure of the WbkC formyl transferase from Brucella melitensis 分子名称: (6R)-2-amino-6-methyl-5,6,7,8-tetrahydropteridin-4(3H)-one, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Riegert, A.S, Chantigian, D.P, Thoden, J.B, Holden, H.M. 登録日 2017-05-26 公開日 2017-07-05 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Biochemical Characterization of WbkC, an N-Formyltransferase from Brucella melitensis. Biochemistry, 56, 2017
5VZ0	Crystal structure of Lactococcus lactis pyruvate carboxylase G746A mutant in complex with cyclic-di-AMP 分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Choi, P.H, Tong, L. 登録日 2017-05-26 公開日 2017-08-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and functional studies of pyruvate carboxylase regulation by cyclic di-AMP in lactic acid bacteria. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W0C	Cytochrome P450 (CYP) 2C9 TCA007 Inhibitor Complex 分子名称: Cytochrome P450 2C9, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Johnson, E.F, Hsu, M.-H. 登録日 2017-05-30 公開日 2017-09-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes. Angew. Chem. Int. Ed. Engl., 56, 2017
5W68	Type II secretin from Enteropathogenic Escherichia coli - GspD 分子名称: Putative type II secretion protein 著者 Hay, I.D, Belousoff, M.J, Dunstan, R, Bamert, R, Lithgow, T. 登録日 2017-06-16 公開日 2017-11-15 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure and Membrane Topography of the Vibrio-Type Secretin Complex from the Type 2 Secretion System of Enteropathogenic Escherichia coli. J. Bacteriol., 200, 2018
5W55	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JWG048 分子名称: 1,2-ETHANEDIOL, 11-ethyl-2-({2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Bromodomain-containing protein 4 著者 Xu, X, Blacklow, S.C. 登録日 2017-06-14 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.354 Å) 主引用文献 Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JWG048 To Be Published
5W60	Crystal structure of BAXP168G monomer cryo-protected with ethylene glycol 分子名称: Apoptosis regulator BAX, SULFATE ION 著者 Robin, A.Y, Colman, P.M, Czabotar, P.E. 登録日 2017-06-16 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
5W4D	C. japonica N-domain, Selenomethionine mutant 分子名称: 1,2-ETHANEDIOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, CHLORIDE ION, ... 著者 Aoki, S.T, Bingman, C.A, Kimble, J. 登録日 2017-06-10 公開日 2018-06-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.599 Å) 主引用文献 C. elegans germ granules require both assembly and localized regulators for mRNA repression. Nat Commun, 12, 2021
5W5J	Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases 分子名称: N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 2, SULFATE ION 著者 Kreusch, A, Spraggon, G. 登録日 2017-06-15 公開日 2017-10-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett, 8, 2017
5W5F	Cryo-EM structure of the T4 tail tube 分子名称: Tail tube protein gp19 著者 Zheng, W, Wang, F, Taylor, N.M, Guerrero-Ferreira, R.C, Leiman, P.G, Egelman, E.H. 登録日 2017-06-15 公開日 2017-08-16 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Refined Cryo-EM Structure of the T4 Tail Tube: Exploring the Lowest Dose Limit. Structure, 25, 2017
5W61	Crystal structure of BAXP168G monomer co-crystallized with glycerol 分子名称: Apoptosis regulator BAX 著者 Robin, A.Y, Colman, P.M, Czabotar, P.E. 登録日 2017-06-16 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
5W63	Crystal structure of channel catfish BAX 分子名称: 1,2-ETHANEDIOL, Apoptosis regulator bax, SULFATE ION 著者 Robin, A.Y, Colman, P.M, Czabotar, P.E, Luo, C.S. 登録日 2017-06-16 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.436 Å) 主引用文献 Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
5VTO	Solution Structure of BlsM 分子名称: Blasticidin M 著者 Kang, M, Doddapaneni, K, Heppner, Z, Wu, Z. 登録日 2017-05-17 公開日 2018-05-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the NUCLEOTIDE hydrolase BlsM: Implication of its Substrate Specificity To Be Published
5VKG	Solution-state NMR structural ensemble of human Tsg101 UEV in complex with tenatoprazole 分子名称: 4-methoxy-1-(5-methoxy-3H-imidazo[4,5-b]pyridin-2-yl)-3,5-dimethyl-2-(sulfanylmethyl)pyridin-1-ium, Tumor susceptibility gene 101 protein 著者 Strickland, M, Ehrlich, L.S, Watanabe, S, Khan, M, Strub, M.-P, Luan, C.H, Powell, M.D, Leis, J, Tjandra, N, Carter, C. 登録日 2017-04-21 公開日 2017-11-15 最終更新日 2024-10-30 実験手法 SOLUTION NMR 主引用文献 Tsg101 chaperone function revealed by HIV-1 assembly inhibitors. Nat Commun, 8, 2017
5VF0	Solution NMR structure of human RAD18 (198-240) in complex with ubiquitin 分子名称: E3 ubiquitin-protein ligase RAD18, Polyubiquitin-B, ZINC ION 著者 Hu, Q, Botuyan, M.V, Mer, G. 登録日 2017-04-06 公開日 2017-05-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18. Mol. Cell, 66, 2017
5VLN	NMR structure of the N-domain of troponin C bound to switch region of troponin I 分子名称: Troponin C, slow skeletal and cardiac muscles,Troponin I, cardiac muscle 著者 Cai, F, Hwang, P.M, Sykes, B.D. 登録日 2017-04-25 公開日 2017-05-24 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structures reveal details of small molecule binding to cardiac troponin. J. Mol. Cell. Cardiol., 101, 2016
6D9Z	Structure of CysZ, a sulfate permease from Pseudomonas Denitrificans 分子名称: Sulfate transporter CysZ, octyl beta-D-glucopyranoside 著者 Sanghai, Z.A, Clarke, O.B, Liu, Q, Banerjee, S, Rajashankar, K.R, Hendrickson, W.A, Mancia, F. 登録日 2018-04-30 公開日 2018-05-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.4021318 Å) 主引用文献 Structure-based analysis of CysZ-mediated cellular uptake of sulfate. Elife, 7, 2018
5W3N	Molecular structure of FUS low sequence complexity domain protein fibrils 分子名称: RNA-binding protein FUS 著者 Murray, D.T, Kato, M, Lin, Y, Thurber, K, Hung, I, McKnight, S, Tycko, R. 登録日 2017-06-08 公開日 2017-09-27 最終更新日 2024-05-15 実験手法 SOLID-STATE NMR 主引用文献 Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains. Cell, 171, 2017
5VNT	Solution NMR Structure of the C-terminal Headpiece Domain of Villin 4 from A.thaliana, the First Non-Vertebrate Headpiece Structure 分子名称: Villin-4 著者 Miears, H.L, Smirnov, S.L. 登録日 2017-05-01 公開日 2017-05-10 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Plant Villin Headpiece Domain Demonstrates a Novel Surface Charge Pattern and High Affinity for F-Actin. Biochemistry, 57, 2018
5W0Y	Solution NMR Structure of a Class I Hydrophobin from Serpula lacrymans 分子名称: Hydrophobin 著者 Kenward, C, Langelaan, D.N. 登録日 2017-06-01 公開日 2018-06-06 最終更新日 2024-10-23 実験手法 SOLUTION NMR 主引用文献 Characterization of the structure and self-assembly of two distinct class IB hydrophobins. Appl.Microbiol.Biotechnol., 106, 2022
5VSO	NMR structure of Ydj1 J-domain, a cytosolic Hsp40 from Saccharomyces cerevisiae 分子名称: Yeast dnaJ protein 1 著者 Ciesielski, S.J, Tonelli, M, Lee, W, Cornilescu, G, Markley, J.L, Schilke, B.A, Ziegelhoffer, T, Craig, E.A. 登録日 2017-05-12 公開日 2017-11-01 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Broadening the functionality of a J-protein/Hsp70 molecular chaperone system. PLoS Genet., 13, 2017

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