2CGO
 
 | | FACTOR INHIBITING HIF-1 ALPHA with fumarate | | 分子名称: | FE (III) ION, FUMARIC ACID, HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR, ... | | 著者 | McDonough, M.A, Clifton, I.J, Schofield, C.J. | | 登録日 | 2006-03-09 | | 公開日 | 2006-12-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and Mechanistic Studies on the Inhibition of the Hypoxia-Inducible Transcription Factor Hydroxylases by Tricarboxylic Acid Cycle Intermediates.
J.Biol.Chem., 282, 2007
|
|
2CGN
 | | FACTOR INHIBITING HIF-1 ALPHA with succinate | | 分子名称: | FE (III) ION, HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR, SUCCINIC ACID, ... | | 著者 | McDonough, M.A, Clifton, I.J, Schofield, C.J. | | 登録日 | 2006-03-09 | | 公開日 | 2006-12-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and Mechanistic Studies on the Inhibition of the Hypoxia-Inducible Transcription Factor Hydroxylases by Tricarboxylic Acid Cycle Intermediates.
J.Biol.Chem., 282, 2007
|
|
6U1N
 | | GPCR-Beta arrestin structure in lipid bilayer | | 分子名称: | 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, Beta-arrestin-1, Fab30 heavy chain, ... | | 著者 | Staus, D.P, Hu, H, Robertson, M.J, Kleinhenz, A.L.W, Wingler, L.M, Capel, W.D, Latorraca, N.R, Lefkowitz, R.J, Skiniotis, G. | | 登録日 | 2019-08-16 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure of the M2 muscarinic receptor-beta-arrestin complex in a lipid nanodisc.
Nature, 579, 2020
|
|
8SNB
 | |
8BZM
 | | FOXK1-ELF1-heterodimer bound to DNA | | 分子名称: | DNA, ETS-related transcription factor Elf-1, Forkhead box protein K1, ... | | 著者 | Morgunova, E, Popov, A, Yin, Y, Taipale, J. | | 登録日 | 2022-12-15 | | 公開日 | 2023-12-27 | | 最終更新日 | 2025-04-23 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | DNA-guided transcription factor interactions extend human gene regulatory code.
Nature, 2025
|
|
2F3D
 | | Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ... | | 著者 | Iancu, C.V, Mukund, S, Choe, J.-Y, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2005-11-21 | | 公開日 | 2006-04-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Mechanism of displacement of a catalytically essential loop from the active site of mammalian fructose-1,6-bisphosphatase.
Biochemistry, 52, 2013
|
|
2F3B
 | | Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, PHOSPHATE ION, ... | | 著者 | Iancu, C.V, Mukund, S, Choe, J.-Y, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2005-11-20 | | 公開日 | 2006-04-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mechanism of displacement of a catalytically essential loop from the active site of mammalian fructose-1,6-bisphosphatase.
Biochemistry, 52, 2013
|
|
1NV3
 | | Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate and Thallium (100 mM) | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, MAGNESIUM ION, ... | | 著者 | Choe, J, Iancu, C.V, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2003-02-02 | | 公開日 | 2003-07-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Interaction of Tl+ with product complexes of fructose-1,6-bisphosphatase
J.BIOL.CHEM., 278, 2003
|
|
1NUZ
 | | Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate and Phosphate | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, MAGNESIUM ION, ... | | 著者 | Choe, J, Iancu, C.V, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2003-02-01 | | 公開日 | 2003-07-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Interaction of Tl+ with product complexes of fructose-1,6-bisphosphatase
J.BIOL.CHEM., 278, 2003
|
|
1NV7
 | | Fructose-1,6-Bisphosphatase Complex With AMP, Magnesium, Fructose-6-Phosphate, Phosphate and Thallium (20 mM) | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-Bisphosphatase, ... | | 著者 | Choe, J, Iancu, C.V, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2003-02-02 | | 公開日 | 2003-07-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Interaction of Tl+ with product complexes of fructose-1,6-bisphosphatase
J.BIOL.CHEM., 278, 2003
|
|
1NV4
 | | Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate, EDTA and Thallium (1 mM) | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, MAGNESIUM ION, ... | | 著者 | Choe, J, Iancu, C.V, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2003-02-02 | | 公開日 | 2003-07-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Interaction of Tl+ with product complexes of fructose-1,6-bisphosphatase
J.BIOL.CHEM., 278, 2003
|
|
1NV6
 | | Fructose-1,6-Bisphosphatase Complex With Magnesium, Fructose-6-Phosphate, Phosphate, EDTA and Thallium (20 mM) | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-Bisphosphatase, HYDROGENPHOSPHATE ION, ... | | 著者 | Choe, J, Iancu, C.V, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2003-02-02 | | 公開日 | 2003-07-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Interaction of Tl+ with product complexes of fructose-1,6-bisphosphatase
J.BIOL.CHEM., 278, 2003
|
|
1NUY
 | | Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, and Phosphate | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, MAGNESIUM ION, ... | | 著者 | Choe, J, Iancu, C.V, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2003-02-01 | | 公開日 | 2003-07-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Metaphosphate in the active site of fructose-1,6-bisphosphatase
J.BIOL.CHEM., 278, 2003
|
|
1NV0
 | | Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate and 1 mM Thallium | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, MAGNESIUM ION, ... | | 著者 | Choe, J, Iancu, C.V, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2003-02-01 | | 公開日 | 2003-07-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Interaction of Tl+ with product complexes of fructose-1,6-bisphosphatase
J.BIOL.CHEM., 278, 2003
|
|
1NUW
 | | Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate and Phosphate at pH 9.6 | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, MAGNESIUM ION, ... | | 著者 | Choe, J, Iancu, C.V, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2003-02-01 | | 公開日 | 2003-07-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Metaphosphate in the active site of fructose-1,6-bisphosphatase
J.BIOL.CHEM., 278, 2003
|
|
1NUX
 | | Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate and inhibitory concentrations of Potassium (200mM) | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, MAGNESIUM ION, ... | | 著者 | Choe, J, Iancu, C.V, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2003-02-01 | | 公開日 | 2003-07-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Metaphosphate in the active site of fructose-1,6-bisphosphatase
J.BIOL.CHEM., 278, 2003
|
|
1AWI
 | |
2C9O
 | | 3D Structure of the human RuvB-like helicase RuvBL1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RUVB-LIKE 1 | | 著者 | Matias, P.M, Gorynia, S, Donner, P, Carrondo, M.A. | | 登録日 | 2005-12-14 | | 公開日 | 2006-10-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the human AAA+ protein RuvBL1.
J. Biol. Chem., 281, 2006
|
|
2XUM
 | | FACTOR INHIBITING HIF (FIH) Q239H MUTANT IN COMPLEX WITH ZN(II), NOG AND ASP-SUBSTRATE PEPTIDE (20-MER) | | 分子名称: | ASP-SUBSTRATE PEPTIDE 2, HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR, N-OXALYLGLYCINE, ... | | 著者 | Chowdhury, R, McDonough, M.A, Schofield, C.J. | | 登録日 | 2010-10-19 | | 公開日 | 2010-12-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor.
J. Biol. Chem., 286, 2011
|
|
3PY3
 | |
4F0Z
 | | Crystal Structure of Calcineurin in Complex with the Calcineurin-Inhibiting Domain of the African Swine Fever Virus Protein A238L | | 分子名称: | Ankyrin repeat domain-containing protein A238L, CALCIUM ION, Calcineurin subunit B type 1, ... | | 著者 | Grigoriu, S, Peti, W, Page, R. | | 登録日 | 2012-05-05 | | 公開日 | 2013-03-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The molecular mechanism of substrate engagement and immunosuppressant inhibition of calcineurin.
Plos Biol., 11, 2013
|
|
3P57
 | | Crystal structure of the p300 TAZ2 domain bound to MEF2 on DNA | | 分子名称: | DNA (5'-D(*A*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3'), Histone acetyltransferase p300, ... | | 著者 | He, J, Ye, J, Riquelme, C, Liu, J.O. | | 登録日 | 2010-10-08 | | 公開日 | 2011-08-10 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.1921 Å) | | 主引用文献 | Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly.
Nucleic Acids Res., 39, 2011
|
|
8D7I
 | | Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap1 from S. aureus | | 分子名称: | Cathepsin G, C-terminal truncated form, Extracellular Adherence Protein, ... | | 著者 | Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. | | 登録日 | 2022-06-07 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.63 Å) | | 主引用文献 | S. aureus Eap is a polyvalent inhibitor of neutrophil serine proteases.
J.Biol.Chem., 300, 2024
|
|
8D7K
 | | Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap2 from S. aureus | | 分子名称: | Cathepsin G, C-terminal truncated form, Extracellular Adherence Protein, ... | | 著者 | Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. | | 登録日 | 2022-06-07 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | S. aureus Eap is a polyvalent inhibitor of neutrophil serine proteases.
J.Biol.Chem., 300, 2024
|
|
8UJY
 | | Crystal structure of human WD repeat-containing protein 5 in complex with 4-(3,5-dimethoxybenzyl)-9-(4-fluoro-2-methylphenyl)-7-((2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl)methyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one (compound 8) | | 分子名称: | (9P)-4-[(3,5-dimethoxyphenyl)methyl]-9-(4-fluoro-2-methylphenyl)-7-{[(2E)-2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl]methyl}-3,4-dihydro-1,4-benzoxazepin-5(2H)-one, WD repeat-containing protein 5 | | 著者 | Zhao, B, Amporndanai, K, Fesik, S.W. | | 登録日 | 2023-10-11 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors.
J.Med.Chem., 66, 2023
|
|
