PDB: 45522 件ウェブページステータス検索Chemie searchBIRD

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3OP5	Human vaccinia-related kinase 1 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Serine/threonine-protein kinase VRK1, ... 著者 Allerston, C.K, Uttarkar, S, Savitsky, P, Elkins, J.M, Filippakopoulos, P, Krojer, T, Rellos, P, Fedorov, O, Eswaran, J, Brenner, B, Keates, T, Das, S, King, O, Chalk, R, Berridge, G, von Delft, F, Gileadi, O, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2010-08-31 公開日 2010-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations. Sci Rep, 7, 2017
3P7F	Structure of the human Langerin carbohydrate recognition domain 分子名称: C-type lectin domain family 4 member K, CALCIUM ION 著者 Skerra, A, Schiefner, A. 登録日 2010-10-12 公開日 2010-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site. Mol.Immunol., 45, 2008
3PDK	crystal structure of phosphoglucosamine mutase from B. anthracis 分子名称: PHOSPHATE ION, Phosphoglucosamine mutase 著者 Mehra-Chaudhary, R, Mick, J, Tanner, J.J, Henzl, M, Beamer, L.J. 登録日 2010-10-22 公開日 2011-08-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of Bacillus anthracis Phosphoglucosamine Mutase, an Enzyme in the Peptidoglycan Biosynthetic Pathway. J.Bacteriol., 193, 2011
3PE8	Crystal structure of Enoyl-CoA hydratase from Mycobacterium smegmatis 分子名称: 1,2-ETHANEDIOL, Enoyl-CoA hydratase, ZINC ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-10-25 公開日 2010-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3PJ8	Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine. 分子名称: (2R)-2-{[7-(benzylamino)-3-(propan-2-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]amino}butan-1-ol, Cell division protein kinase 2 著者 McNae, I.W, Jorda, R, Havlicek, L, Strnad, M, Voller, J, Walkinshaw, M.D, Krystof, V. 登録日 2010-11-09 公開日 2011-04-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity. J.Med.Chem., 54, 2011
3PDN	Crystal structure of SmyD3 in complex with methyltransferase inhibitor sinefungin 分子名称: GLYCEROL, MAGNESIUM ION, SET and MYND domain-containing protein 3, ... 著者 Sirinupong, N, Brunzelle, J, Yang, Z. 登録日 2010-10-23 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Insights into the Autoinhibition and Posttranslational Activation of Histone Methyltransferase SmyD3. J.Mol.Biol., 406, 2011
3PJS	Mechanism of Activation Gating in the Full-Length KcsA K+ Channel 分子名称: FAB heavy chain, FAB light chain, Voltage-gated potassium channel 著者 Uysal, S, Cuello, L.G, Kossiakoff, A, Perozo, E. 登録日 2010-11-10 公開日 2011-07-06 最終更新日 2011-08-03 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Mechanism of activation gating in the full-length KcsA K+ channel. Proc.Natl.Acad.Sci.USA, 108, 2011
3PF5	Crystal structure of Bs-CspB in complex with rU6 分子名称: Cold shock protein cspB, MAGNESIUM ION, hexaribouracil (rU6) 著者 Sachs, R, Max, K.E.A, Heinemann, U. 登録日 2010-10-27 公開日 2011-09-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution. Rna, 18, 2012
3PVG	Crystal structure of Z. mays CK2 alpha subunit in complex with the inhibitor 4,5,6,7-tetrabromo-1-carboxymethylbenzimidazole (K68) 分子名称: (4,5,6,7-tetrabromo-1H-benzimidazol-1-yl)acetic acid, Casein kinase II subunit alpha 著者 Papinutto, E, Franchin, C, Battistutta, R. 登録日 2010-12-07 公開日 2010-12-15 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 ATP site-directed inhibitors of protein kinase CK2: an update. Curr Top Med Chem, 11, 2011
3PGG	Crystal structure of cryptosporidium parvum u6 snrna-associated sm-like protein lsm5 分子名称: U6 snRNA-associated Sm-like protein LSm5. SM domain 著者 Dong, A, Gao, M, Zhao, Y, Lew, J, Wasney, G.A, Kozieradzki, I, Vedadi, M, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J, Structural Genomics Consortium (SGC) 登録日 2010-11-01 公開日 2011-02-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Genome-Scale Protein Expression and Structural Biology of Plasmodium Falciparum and Related Apicomplexan Organisms. Mol.Biochem.Parasitol., 151, 2007
3DD6	Crystal structure of Rph, an exoribonuclease from Bacillus anthracis at 1.7 A resolution 分子名称: Ribonuclease PH, SULFATE ION 著者 Rawlings, A.E, Blagova, E.V, Levdikov, V.M, Fogg, M.J, Wilson, K.S, Wilkinson, A.J, Structural Proteomics in Europe 2 (SPINE-2) 登録日 2008-06-05 公開日 2009-02-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.702 Å) 主引用文献 The structure of Rph, an exoribonuclease from Bacillus anthracis, at 1.7 A resolution. Acta Crystallogr.,Sect.F, 65, 2009
3PRM	Structural analysis of a viral OTU domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with human ubiquitin 分子名称: Polyubiquitin-B (Fragment), RNA-directed RNA polymerase L 著者 Capodagli, G.C, McKercher, M.A, Baker, E.A, Masters, E.M, Brunzelle, J.S, Pegan, S.D. 登録日 2010-11-30 公開日 2011-01-26 最終更新日 2023-02-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural analysis of a viral ovarian tumor domain protease from the crimean-congo hemorrhagic Fever virus in complex with covalently bonded ubiquitin. J.Virol., 85, 2011
3DCV	Crystal structure of human Pim1 kinase complexed with 4-(4-hydroxy-3-methyl-phenyl)-6-phenylpyrimidin-2(1H)-one 分子名称: 4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one, Proto-oncogene serine/threonine-protein kinase Pim-1 著者 Bellamacina, C.R, Shafer, C.M, Lindvall, M, Gesner, T.G, Yabannavar, A, Weiping, J, Song, L, Walter, A. 登録日 2008-06-04 公開日 2008-08-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 4-(1H-indazol-5-yl)-6-phenylpyrimidin-2(1H)-one analogs as potent CDC7 inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
3DDW	Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK055 分子名称: (2S)-{[(3-{[(2-chloro-6-methylphenyl)carbamoyl]amino}naphthalen-2-yl)carbonyl]amino}(phenyl)ethanoic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... 著者 Nolte, R.T. 登録日 2008-06-06 公開日 2009-01-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy. Bioorg.Med.Chem.Lett., 19, 2009
2QKV	Crystal Structure of the C645S Mutant of the 5th PDZ Domain of InaD 分子名称: Inactivation-no-after-potential D protein 著者 Ranganathan, R, Socolich, M. 登録日 2007-07-11 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Dynamic Scaffolding in a G Protein-Coupled Signaling System. Cell(Cambridge,Mass.), 131, 2007
3DE6	Proteinase K by Classical hanging drop method after the third step of high X-Ray dose on ESRF ID23-1 beamline 分子名称: CALCIUM ION, Proteinase K 著者 Pechkova, E, Tripathi, S.K, Nicolini, C. 登録日 2008-06-08 公開日 2009-06-09 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Radiation stability of proteinase K crystals grown by LB nanotemplate method J.Struct.Biol., 168, 2009
3PQE	Crystal structure of L-lactate dehydrogenase from Bacillus subtilis with H171C mutation 分子名称: L-lactate dehydrogenase 著者 Zhang, Y, Garavito, R.M. 登録日 2010-11-26 公開日 2011-12-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of L-lactate dehydrogenase from Bacillus subtilis with H171C mutation To be Published
2QNX	Crystal structure of the complex between the mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and 11-[(decyloxycarbonyl)dithio]-undecanoic acid 分子名称: 11-MERCAPTOUNDECANOIC ACID, 3-oxoacyl-[acyl-carrier-protein] synthase 3, O-DECYL HYDROGEN THIOCARBONATE 著者 Sachdeva, S, Musayev, F, Alhamadsheh, M, Scarsdale, J.N, Wright, H.T, Reynolds, K.A. 登録日 2007-07-19 公開日 2008-05-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH Chem.Biol., 15, 2008
3PQV	Cyclase homolog 分子名称: D(-)-TARTARIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Tanaka, N, Smith, P, Shuman, S. 登録日 2010-11-27 公開日 2011-04-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.609 Å) 主引用文献 Crystal structure of Rcl1, an essential component of the eukaryal pre-rRNA processosome implicated in 18s rRNA biogenesis. Rna, 17, 2011
3PZZ	Structure of an amyloid forming peptide GAIIGL (29-34) from amyloid beta 分子名称: Amyloid beta A4 protein 著者 Soriaga, A.B, Laganowsky, A.L, Sawaya, M.R, Eisenberg, D. 登録日 2010-12-14 公開日 2011-10-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Molecular basis for amyloid-beta polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
3D9Y	Crystal Structure of Profilin from Schizosaccharomyces pombe 分子名称: GLYCEROL, Profilin 著者 Ezezika, O.C, Nolen, B.J, Pollard, T.D. 登録日 2008-05-28 公開日 2008-12-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Incompatibility with Formin Cdc12p Prevents Human Profilin from Substituting for Fission Yeast Profilin: INSIGHTS FROM CRYSTAL STRUCTURES OF FISSION YEAST PROFILIN. J.Biol.Chem., 284, 2009
2QSP	Bovine Hemoglobin at pH 5.7 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Aranda IV, R, Richards, M.P, Phillips Jr, G.N. 登録日 2007-07-31 公開日 2008-09-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss. Proteins, 75, 2008
3DB1	Crystal structure of the 2H-phosphatase domain of Sts-2 in complex with phosphate 分子名称: PHOSPHATE ION, STS-2 protein 著者 Nassar, N, Chen, Y, Carpino, N. 登録日 2008-05-30 公開日 2009-03-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Structural and functional characterization of the 2H-phosphatase domain of Sts-2 reveals an acid-dependent phosphatase activity. Biochemistry, 48, 2009
2QUH	Crystal structures of human tryptophanyl-tRNA synthetase in complex with Trp 分子名称: TRYPTOPHAN, Tryptophanyl-tRNA synthetase 著者 Shen, N, Ding, J.P. 登録日 2007-08-05 公開日 2008-04-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states Nucleic Acids Res., 36, 2008
3D84	Structural Analysis of a Holo Enzyme Complex of Mouse Dihydrofolate Reductase with NADPH and a Ternary Complex with the Potent and Selective Inhibitor 2.4-Diamino-6-(-2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine 分子名称: Dihydrofolate reductase, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cody, V. 登録日 2008-05-22 公開日 2008-09-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of a holoenzyme complex of mouse dihydrofolate reductase with NADPH and a ternary complex with the potent and selective inhibitor 2,4-diamino-6-(2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine. Acta Crystallogr.,Sect.D, 64, 2008

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